Selected Topics in DNA Repair


Book Description

This book is intended for students and scientists working in the field of DNA repair, focusing on a number of topics ranging from DNA damaging agents and mechanistic insights to methods in DNA repair and insights into therapeutic strategies. These topics demonstrate how scientific ideas are developed, tested, dialogued, and matured as it is meant to discuss key concepts in DNA repair. The book should serve as a supplementary text in courses and seminars as well as a general reference for biologists with an interest in DNA repair.




An American Sickness


Book Description

A New York Times bestseller/Washington Post Notable Book of 2017/NPR Best Books of 2017/Wall Street Journal Best Books of 2017 "This book will serve as the definitive guide to the past and future of health care in America.”—Siddhartha Mukherjee, Pulitzer Prize-winning author of The Emperor of All Maladies and The Gene At a moment of drastic political upheaval, An American Sickness is a shocking investigation into our dysfunctional healthcare system - and offers practical solutions to its myriad problems. In these troubled times, perhaps no institution has unraveled more quickly and more completely than American medicine. In only a few decades, the medical system has been overrun by organizations seeking to exploit for profit the trust that vulnerable and sick Americans place in their healthcare. Our politicians have proven themselves either unwilling or incapable of reining in the increasingly outrageous costs faced by patients, and market-based solutions only seem to funnel larger and larger sums of our money into the hands of corporations. Impossibly high insurance premiums and inexplicably large bills have become facts of life; fatalism has set in. Very quickly Americans have been made to accept paying more for less. How did things get so bad so fast? Breaking down this monolithic business into the individual industries—the hospitals, doctors, insurance companies, and drug manufacturers—that together constitute our healthcare system, Rosenthal exposes the recent evolution of American medicine as never before. How did healthcare, the caring endeavor, become healthcare, the highly profitable industry? Hospital systems, which are managed by business executives, behave like predatory lenders, hounding patients and seizing their homes. Research charities are in bed with big pharmaceutical companies, which surreptitiously profit from the donations made by working people. Patients receive bills in code, from entrepreneurial doctors they never even saw. The system is in tatters, but we can fight back. Dr. Elisabeth Rosenthal doesn't just explain the symptoms, she diagnoses and treats the disease itself. In clear and practical terms, she spells out exactly how to decode medical doublespeak, avoid the pitfalls of the pharmaceuticals racket, and get the care you and your family deserve. She takes you inside the doctor-patient relationship and to hospital C-suites, explaining step-by-step the workings of a system badly lacking transparency. This is about what we can do, as individual patients, both to navigate the maze that is American healthcare and also to demand far-reaching reform. An American Sickness is the frontline defense against a healthcare system that no longer has our well-being at heart.




On Repentance And Repair


Book Description

Winner NATIONAL JEWISH BOOK AWARDS in Contemporary Jewish Life & Practice Myra H. Kraft Memorial Award A crucial new lens on repentance, atonement, forgiveness, and repair from harm—from personal transgressions to our culture’s most painful and unresolved issues American culture focuses on letting go of grudges and redemption narratives instead of the perpetrator’s obligations or recompense for harmed parties. As survivor communities have pointed out, these emphases have too often only caused more harm. But Danya Ruttenberg knew there was a better model, rooted in the work of the medieval philosopher Maimonides. For Maimonides, upon whose work Ruttenberg elaborates, forgiveness is much less important than the repair work to which the person who caused harm is obligated. The word traditionally translated as repentance really means something more like return, and in this book, returning is a restoration, as much as is possible, to the victim, and, for the perpetrator of harm, a coming back, in humility and intentionality, to behaving as the person we might like to believe we are. Maimonides laid out 5 steps: naming and owning harm; starting to change/transformation; restitution and accepting consequences; apology; and making different choices. Applying this lens to both our personal relationships and some of the most significant and painful issues of our day, including systemic racism and the legacy of enslavement, sexual violence and harassment in the wake of #MeToo, and Native American land rights, On Repentance and Repair helps us envision a way forward. Rooted in traditional Jewish concepts while doggedly accessible and available to people from any, or no, religious background, On Repentance and Repair is a book for anyone who cares about creating a country and culture that is more whole than the one in which we live, and for anyone who has been hurt or who is struggling to take responsibility for their mistakes.




Fixer-Upper


Book Description

Practical ideas to provide affordable housing to more Americans Much ink has been spilled in recent years talking about political divides and inequality in the United States. But these discussions too often miss one of the most important factors in the divisions among Americans: the fundamentally unequal nature of the nation’s housing systems. Financially well-off Americans can afford comfortable, stable homes in desirable communities. Millions of other Americans cannot. And this divide deepens other inequalities. Increasingly, important life outcomes—performance in school, employment, even life expectancy—are determined by where people live and the quality of homes they live in. Unequal housing systems didn’t just emerge from natural economic and social forces. Public policies enacted by federal, state, and local governments helped create and reinforce the bad housing outcomes endured by too many people. Taxes, zoning, institutional discrimination, and the location and quality of schools, roads, public transit, and other public services are among the policies that created inequalities in the nation’s housing patterns. Fixer-Upper is the first book assessing how the broad set of local, state, and national housing policies affect people and communities. It does more than describe how yesterday’s policies led to today’s problems. It proposes practical policy changes than can make stable, decent-quality housing more available and affordable for all Americans in all communities. Fixing systemic problems that arose over decades won’t be easy, in large part because millions of middle-class Americans benefit from the current system and feel threatened by potential changes. But Fixer-Upper suggests ideas for building political coalitions among diverse groups that share common interests in putting better housing within reach for more Americans, building a more equitable and healthy country.




Model Rules of Professional Conduct


Book Description

The Model Rules of Professional Conduct provides an up-to-date resource for information on legal ethics. Federal, state and local courts in all jurisdictions look to the Rules for guidance in solving lawyer malpractice cases, disciplinary actions, disqualification issues, sanctions questions and much more. In this volume, black-letter Rules of Professional Conduct are followed by numbered Comments that explain each Rule's purpose and provide suggestions for its practical application. The Rules will help you identify proper conduct in a variety of given situations, review those instances where discretionary action is possible, and define the nature of the relationship between you and your clients, colleagues and the courts.




The Federal Reporter


Book Description

Includes cases argued and determined in the District Courts of the United States and, Mar./May 1880-Oct./Nov. 1912, the Circuit Courts of the United States; Sept./Dec. 1891-Sept./Nov. 1924, the Circuit Courts of Appeals of the United States; Aug./Oct. 1911-Jan./Feb. 1914, the Commerce Court of the United States; Sept./Oct. 1919-Sept./Nov. 1924, the Court of Appeals of the District of Columbia.




DNA Recombination and Repair


Book Description

The processes of DNA recombination and repair are vital to cell integrity - an error can lead to disease such as cancer. It is therefore a large and exciting area of research and is also taught on postgraduate and undergraduate courses. This book is not a comprehensive view of the field, but a selection of the issues currently at the forefront of knowledge.







The Big Fix


Book Description

A “smart, honest, and down-to-earth” (Elizabeth Kolbert) citizen’s guide to the seven urgent changes that will really make a difference for our climate. If you think the only thing you can do to combat climate change is to install a smart thermostat or cook plant-based meat, you’re thinking too small. In The Big Fix, energy policy advisor Hal Harvey and longtime New York Times reporter Justin Gillis offer a new, hopeful way to engage with one of the greatest problems of our age. Writing in a lively, accessible style, the pair illuminate how the really big decisions that affect our climate get made—whether by the most obscure public utilities commissions or in the lofty halls of state capitols—and reveal how each of us can influence these decisions to deliver change. The pair focus on the seven areas of our political economy where ambitious but practical changes will have the greatest effect: from what kind of power plants to build to how much insulation new houses require to how efficient cars must be before they’re allowed on the road. Equal parts pragmatic and inspiring—and “full of illustrative stories and compelling evidence” (Al Gore)—The Big Fix provides an action plan for anyone serious about holding our governments accountable and saving our threatened planet.




Repairing the Athlete's Image


Book Description

Repairing the Athlete’s Image: Studies in Sports Image Restoration, edited by Joseph R. Blaney, Lance Lippert, and J. Scott Smith, offers twenty-one case studies and conceptual frameworks about athletes and their organizations as they attempt to mitigate the effects of malfeasance. Employing traditional Image Restoration Theory (IRT) approaches to athletic communication (and other innovative approaches), the contributors to this volume add to our understanding of which communicative strategies work best for athletes when their reputations are sullied. This comprehensive text presents case studies of varying athletes, sports, and public relations scenarios with prescriptive advice for those attempting to repair athletic reputations. The contributors variously explore such controversies and mischief as the steroids accusations lobbed at Barry Bonds and Roger Clemens, the Michael Phelps marijuana controversy, the sexual misconduct of Tiger Woods and Kobe Bryant, and other topical subjects in sports communication and image repair. While this book will be useful for athletes, coaches, managers, and agents in varying athletic endeavors and levels, it is also a dream collection for teachers and scholars of sports communication. The subjects examined in this study span country, gender, and popularity of sport (not to mention a healthy variety of types of accusations.) Repairing the Athlete’s Image is an essential resource for graduate and upper-level undergraduate courses in sports communication and popular culture.