Evidence-based Research Methods for Chinese Medicine


Book Description

This book is a practical guide to the evidence-based medicine (EBM) research methods that are applicable to Chinese medicine (CM). It includes 3 parts: clinical research, healthcare data research and laboratory research. In each chapter, it explains how to acquire, analyze and evaluate a specific kind of CM research result. Authors exemplify the most important methods with successful cases in transforming reliable data into new knowledge of CM. This book emphasizes the requirements for CM researchers to design and conduct CM studies by following the best available principles, standards and guidelines.




Research Design in Chinese Medicine


Book Description

Research Design in Chinese Medicine: Linking Social and Health Sciences is an innovative and comprehensive guide that bridges the ancient wisdom of Traditional Chinese Medicine (TCM) with modern research methods in social and health sciences. Authored by an expert with a background in Chinese medicine and a doctorate in education from Johns Hopkins University, this book is set to revolutionize the way TCM is studied and practiced in the contemporary world. Designed for a diverse readership, from TCM students and practitioners to those in social sciences and holistic medicine, the book provides a unique integration of traditional techniques and modern research approaches. It offers invaluable resources for Doctor of Acupuncture and Herbal Medicine (DAHM) students, helping them deepen and refine their research skills. Additionally, it serves as an essential academic tool for educators in TCM and related fields, perfectly suited for course adoption in over 50 accredited acupuncture schools within the U.S. and extending its reach globally. Research Design in Chinese Medicine: Linking Social and Health Sciences offers a balanced emphasis on both qualitative and quantitative research approaches. This holistic methodology ensures that readers gain a full spectrum of knowledge, from formulating research questions to conducting ethical studies. The step-by-step guide provided in the book is supplemented with a wealth of resources, including a dedicated website, downloadable templates, and case studies, making it not just a book but a complete learning experience. The book is positioned to be a key resource in the field of TCM research. Its interdisciplinary approach and practical guidance make it invaluable to anyone looking to conduct meaningful research in TCM. The combination of the author's expertise and the practical tools offered makes this book a must-have for students, practitioners, and researchers in the field.




Traditional Herbal Medicine Research Methods


Book Description

This book introduces the methodology for collection and identification of herbal materials, extraction and isolation of compounds from herbs, in vitro bioassay, in vivo animal test, toxicology, and clinical trials of herbal research. To fully understand and make the best use of herbal medicines requires the close combination of chemistry, biochemistry, biology, pharmacology, and clinical science. Although there are many books about traditional medicines research, they mostly focus on either chemical or pharmacological study results of certain plants. This book, however, covers the systematic study and analysis of herbal medicines in general – including chemical isolation and identification, bioassay and mechanism study, pharmacological experiment, and quality control of the raw plant material and end products.




The Way of Thinking in Chinese Medicine


Book Description

Chinese Medicine is an outstanding scientific proposition system with its own structural, methodological and theoretical prerequisites flowing into the specific practices that make Chinese Medicine popular in the Western world. However, we should be aware of the fact that Chinese Medicine is challenged in its existence because it is widely unknown. Fostering the understanding of Chinese Medicine in various aspects is, hence, the main aim of this book that gives interesting insights into the discussions on current developments in Chinese Medicine research.




Chinese Medicine - Modern Practice


Book Description

Annals of Traditional Chinese Medicine is a new book series dedicated to the promotion of evidence-based TCM research. It features quality reports focusing on curriculum design, research methodology, original investigations of the quality, efficacy and safety of TCM, and evidence-based trials for the management of various clinical conditions.The inaugural volume of this series, Chinese Medicine — Modern Practice, contains chapters on Chinese Herbal Medicine (for AIDS, cancer, cardiovascular disease, cerebral haemorrhage and Alzheimer disease), Acupuncture (for drug withdrawal, anaesthesia and analgesia), Research Methodology and Chinese Medicine Education.The book will be of interest to clinicians in western medicine, mainstream medical researchers, other healthcare professionals, Chinese medicine educators, clinical and basic Chinese medicine researchers, and health science students, particularly Chinese medicine students. It will also be an important resource for TCM regulators to obtain reliable and critical information concerning the evaluation of quality, efficacy and safety of clinical modalities of Chinese medicine.




Systems Biology for Traditional Chinese Medicine


Book Description

The application of systems biology methods to Traditional Chinese Medicine Emphasizing the harmony of the human body with the environment, Traditional Chinese Medicine (TCM) has evolved over thousands of years. It is a systemic theory derived from clinical experience, the philosophy of holism and systematology, and the belief that man is an integral part of nature. Systems Biology for Traditional Chinese Medicine describes how the latest methods in systems biology can be applied to TCM, providing a comprehensive resource for the modernization and advancement of TCM as well as general drug discovery efforts. It is the first comprehensive work to propose a system-to-system research methodology to study the interaction between TCM and the human body and its applications in drug research and development. Using three popular traditional Chinese medicines—Shuanglongfang, Qingkailing, and Liushenwan—as examples, the authors set forth case examples demonstrating how to find material groups, perform efficacy screenings, and conduct safety evaluations of TCM. The book also: Describes the mechanisms of TCM at the molecular and systems levels using chemomics, genomics, proteomics, metabolomics, and bioinformatics Places modern scientific technologies within the context of TCM, helping drug researchers improve experimental designs and strategies Illustrates how a systems biology approach is compatible with TCM's traditional, holistic therapeutic strategies and treatment modalities Presents topics of current interest, such as integrated global systems biology and the application of chemometrics research to herbal medicines This book not only opens a new pathway for the continued development of TCM, but also for systems biology. In addition, it fosters collaboration and discussion among Eastern and Western scientists by applying systems biology to TCM.




Quantitative Methods for Traditional Chinese Medicine Development


Book Description

In recent years, many pharmaceutical companies and clinical research organizations have been focusing on the development of traditional Chinese (herbal) medicines (TCMs) as alternatives to treating critical or life-threatening diseases and as pathways to personalized medicine. Quantitative Methods for Traditional Chinese Medicine Development is the first book entirely devoted to the design and analysis of TCM development from a Western perspective, i.e., evidence-based clinical research and development. The book provides not only a comprehensive summary of innovative quantitative methods for developing TCMs but also a useful desk reference for principal investigators involved in personalized medicine. Written by one of the world's most prominent biostatistics researchers, the book connects the pharmaceutical industry, regulatory agencies, and academia. It presents a state-of-the-art examination of the subject for: Scientists and researchers who are engaged in pharmaceutical/clinical research and development of TCMs Those in regulatory agencies who make decisions in the review and approval process of TCM regulatory submissions Biostatisticians who provide statistical support to assess clinical safety and effectiveness of TCMs and related issues regarding quality control and assurance as well as to test for consistency in the manufacturing processes for TCMs This book covers all of the statistical issues encountered at various stages of pharmaceutical/clinical development of a TCM. It explains regulatory requirements; product specifications and standards; and various statistical techniques for evaluation of TCMs, validation of diagnostic procedures, and testing consistency




Recent Advances in Theories and Practice of Chinese Medicine


Book Description

During the recent years, traditional Chinese medicine (TCM) has attracted the attention of researchers all over the world. It is looked upon not only as a bright pearl, but also a treasure house of ancient Chinese culture. Nowadays, TCM has become a subject area with high potential and the possibility for original innovation. This book titled Recent Advances in Theories and Practice of Chinese Medicine provides an authoritative and cutting-edge insight into TCM research, including its basic theories, diagnostic approach, current clinical applications, latest advances, and more. It discusses many often neglected important issues, such as the theory of TCM property, and how to carry out TCM research in the direction of TCM property theory using modern scientific technology. The authors of this book comprise an international group of recognized researchers who possess abundant clinical knowledge and research background due to their years of practicing TCM. Hopefully, this book will help our readers gain a deeper understanding of the unique characteristics of Chinese medicine.




Focus on Chinese Medicine Research


Book Description

Acupuncture is part of traditional Chinese medicine, being wholly described and published around 100 A.D. Modern acupuncture is based on Chinese publications from the Song dynasty period. This treatment arrived in the Western world in the 17th century, and was associated at first with surgery. The transmission of Chinese medicine into the contemporary world and Western languages presents a significant challenge for its preservation and evolution as a distinct medical discipline. The practice of acupuncture is now considered a liberal profession, despite the significant increase in this therapeutics practice recorded between 2000 and 2010. Traditional Chinese medicine is an alternative method to treat several illnesses and diseases, including endometriosis and cerebral ischemia. This book discusses the practices and outcomes of Chinese medicine.




Data Analytics for Traditional Chinese Medicine Research


Book Description

This contributed volume explores how data mining, machine learning, and similar statistical techniques can analyze the types of problems arising from Traditional Chinese Medicine (TCM) research. The book focuses on the study of clinical data and the analysis of herbal data. Challenges addressed include diagnosis, prescription analysis, ingredient discoveries, network based mechanism deciphering, pattern-activity relationships, and medical informatics. Each author demonstrates how they made use of machine learning, data mining, statistics and other analytic techniques to resolve their research challenges, how successful if these techniques were applied, any insight noted and how these insights define the most appropriate future work to be carried out. Readers are given an opportunity to understand the complexity of diagnosis and treatment decision, the difficulty of modeling of efficacy in terms of herbs, the identification of constituent compounds in an herb, the relationship between these compounds and biological outcome so that evidence-based predictions can be made. Drawing on a wide range of experienced contributors, Data Analytics for Traditional Chinese Medicine Research is a valuable reference for professionals and researchers working in health informatics and data mining. The techniques are also useful for biostatisticians and health practitioners interested in traditional medicine and data analytics.