Pathology: A Modern Case Study


Book Description

A unique case-based molecular approach to understanding pathology Pathology: A Modern Case Study is a concise, focused text that emphasizes the molecular and cellular biology essential to understanding the concepts of disease causation. The book includes numerous case studies designed to highlight the role of the pathologist in the team that provides patient care. Pathology: A Modern Case Study examines the role of anatomic, clinical, and molecular pathologists in dedicated chapters and in descriptions of the pathology of specific organ systems. Features Coverage of pathology focuses on modern approaches to common and important diseases Each chapter delivers the most up-to-date advances in pathology Learning aids include chapter summaries and overviews, bolded terms, and a glossary Common clinically relevant disease are highlighted Disease discussion is based on organ compartment and etiology Coverage includes: Disease and the Genome: Genetic, Developmental and Neoplastic Disease Cell Injury, Death and Aging and the Body's Response Environmental Injury Clinical Practice: Anatomic Pathology Clinical Practice: Molecular Pathology Clinical Practice: Molecular Pathology Organ-specific pathology covering all major body systems Molecular pathology Essential for undergraduate medical students and clinicians who wish to expand their knowledge pathology, Pathology: A Modern Case Study delivers valuable coverage that is directly related to a patient’s condition and the clinical practice of pathology.




A History of Pathology


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The Greater OMENTUM


Book Description

Since RUTHERFORD MORISON left us with the concept of the Omentum being the 'abdominal policeman', clinicians have tacitly assumed that they know sufficient about the structure and function of this organ. However interest in the omentum and its relationship to clinical surgery has recently been develop ing. This book examines all aspects with special reference to surgery and should provide a welcome impetus in research and clinical practice. The editors and contributors have produced a book which is comprehensive and well illustrated and contains detailed refer ences to the important original sources - so essential in a work of this nature. It is written for those who wish to share the delight of acquiring knowledge - even about a comparatively humble organ - as well as for practical surgeons. Both will find ample information to arouse their interest and expand their surgical horizons in exciting ways of which they will almost certainly not have dreamt. I welcome a book of this calibre on a subject which deserves our increasing interest. I delight in the fact that it is dedicated to my friend and colleague MARTIN ALLGOWER.




Surgical Pathological Anatomy of Head and Neck Specimens


Book Description

The dissection of surgical specimens from the upper aero digestive tract is often difficult due to the anatomically complicated nature of this area. Local environ ment dictates routes of tumour spread and surgical margins at risk and these features differ for various subsites within this part of the body. Moreover, ade quate investigation of surgical specimens of the upper aero digestive tract requires knowledge of the various types of surgical procedures used for differ ent areas and should provide data that enable the surgeon to correlate preoper atively performed diagnostic imaging with the macroscopic findings obtained postoperatively. The aim of this book is to provide guidelines for the anatomical dissection of specimens from oral and sinonasal cavities, pharynx and larynx. This is done by illustrations that combine drawings of tumours at various anatomical subsites, details of the respective surgical procedures, the specimens thus obtained, and the way to dissect these specimens as shown by colour photographs of surgical specimens handled in the way schematically outlined. The book will be of benefit for pathologists, oral and maxillofacial surgeons, ENT surgeons and residents in training for these specialties. v Contents 1 Introduction . . . . . . . . . . . . . . . . . . . . 1 1 Head and Neck Specimens and Surgical Pathology 3 General Technical Notes 3 Anatomy 2 Oral Cavity . . . . . . 5 Anatomical Subregions 5 5 Lip ....




Enabling America


Book Description

The most recent high-profile advocate for Americans with disabilities, actor Christopher Reeve, has highlighted for the public the economic and social costs of disability and the importance of rehabilitation. Enabling America is a major analysis of the field of rehabilitation science and engineering. The book explains how to achieve recognition for this evolving field of study, how to set priorities, and how to improve the organization and administration of the numerous federal research programs in this area. The committee introduces the "enabling-disability process" model, which enhances the concepts of disability and rehabilitation, and reviews what is known and what research priorities are emerging in the areas of: Pathology and impairment, including differences between children and adults. Functional limitationsâ€"in a person's ability to eat or walk, for example. Disability as the interaction between a person's pathologies, impairments, and functional limitations and the surrounding physical and social environments. This landmark volume will be of special interest to anyone involved in rehabilitation science and engineering: federal policymakers, rehabilitation practitioners and administrators, researchers, and advocates for persons with disabilities.




Sternberg's Diagnostic Surgical Pathology


Book Description

Completely updated, the Fourth Edition of this standard-setting two-volume reference presents the most advanced diagnostic techniques and the latest information on all currently known disease entities. More than 90 preeminent surgical pathologists offer expert advice on the diagnostic evaluation of every type of specimen from every anatomic site. The Fourth Edition contains 3,494 full-color photographs, of which over 1,100 are new. This edition has three distinguished new editors—Joel K. Greenson, MD, Victor E. Reuter, MD, and Mark H. Stoler, MD—and many new contributors. Updates include new immunohistochemical markers for lymphoid neoplasms, current nomenclature for lymphoid tumors, and state-of-the-art molecular genetic tests. A bound-in CD-ROM contains all the images from the book, downloadable to PowerPoint presentations.




Mohs Micrographic Surgery


Book Description

Mohs Micrographic Surgery, an advanced treatment procedure for skin cancer, offers the highest potential for recovery--even if the skin cancer has been previously treated. This procedure is a state-of-the-art treatment in which the physician serves as surgeon, pathologist, and reconstructive surgeon. It relies on the accuracy of a microscope to trace and ensure removal of skin cancer down to its roots. This procedure allows dermatologists trained in Mohs Surgery to see beyond the visible disease and to precisely identify and remove the entire tumor, leaving healthy tissue unharmed. This procedure is most often used in treating two of the most common forms of skin cancer: basal cell carcinoma and squamous cell carcinoma. The cure rate for Mohs Micrographic Surgery is the highest of all treatments for skin cancer--up to 99 percent even if other forms of treatment have failed. This procedure, the most exact and precise method of tumor removal, minimizes the chance of regrowth and lessens the potential for scarring or disfigurement




Understanding Clinical Research


Book Description

A complete guide to understanding and applying clinical research results Ideal for both researchers and healthcare providers Understanding Clinical Research addresses both the operational challenges of clinical trials and the needs of clinicians to comprehend the nuances of research methods to accurately analyze study results. This timely resource covers all aspects of clinical trials--from study design and statistics to regulatory oversight--and it delivers a detailed yet streamlined overview of must-know research topics. The text features an accessible three-part organization that traces the evolution of clinical research and explains the bedrock principles and unique challenges of clinical experimentation and observational research. Reinforcing this content are real-life case examples--drawn from the authors' broad experience--that put chapter concepts into action and contribute to a working knowledge of integral research techniques. FEATURES: The most definitive guide to promoting excellence in clinical research, designed to empower healthcare providers to assess a study's strengths and weaknesses with confidence and apply this knowledge to optimize patient outcomes In-depth coverage of fundamental research methods and protocols from preeminent authorities provides readers with an instructive primer and a springboard for ongoing clinical research education Clear, comprehensive three-part organization: Section One: Evolution of Clinical Research offers a succinct history of clinical trials, drug regulations, and the role of the FDA while covering the impact of information technology and academic research organizations Section Two: Principles of Clinical Experimentation takes you through the typical phases of clinical trials in the development of medical products, from initial human subject research to postapproval surveillance studies Section Three: Observational Research highlights the underlying principles, pitfalls, and methods for case-control studies, cohort studies, registries, and subgroup analyses within randomized trials




Molecular Pathology and the Dynamics of Disease


Book Description

Molecular Pathology and the Dynamics of Disease bridges the basic science of, and primary clinical literature on, human disease. Topics covered include several major disease areas, such as inflammation and host response, vascular disease, obesity, weight regulation and appetite, cancer biology, drug development, and gene- and cell-based therapeutics that are all presented in a way that emphasizes the interplay between clinical care and investigation. As new technologies and techniques are constantly changing and laboratory scientists plays a critical role in validating data used by clinicians in diagnosing patients, this book provides a timely guide that includes a clinical, research and theory perspective. - Assimilates theoretical knowledge with practical lab work - Provides a needed clinical perspective, along with research and theory - Highlights the impact of basic science on the practice of medicine




Guiding the Surgeon's Hand


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