Author : Anders Vahlquist
Publisher : CRC Press
Page : 390 pages
File Size : 34,90 MB
Release : 2007-06-20
Category : Medical
ISBN : 1420021184
This up-to-date reference describes how retinoids and carotenoids function in the skin and how they can be utilized to prevent and treat a wide variety of skin diseases, as well as advance biomedical research in relation to cancer treatment and immunology. Providing an in-depth update on the pharmacology, pharmacodynamics, and new applications of
Author : Ayse Serap Karadag
Publisher : CRC Press
Page : 508 pages
File Size : 40,96 MB
Release : 2019-10-28
Category : Medical
ISBN : 0429852614
Retinoids are valuable drugs in the dermatologic armamentarium, being employed in daily clinical practice. The text provides an in-depth update on the latest thinking on pharmacology, clinical use, side effects, and follow-up of retinoid therapy in dermatology; it also addresses topics related to retinoid use in special circumstances, such as vulnerable populations, concomitant surgery, and aesthetic procedures. CONTENTS: The background of retinoids * Mechanism of action of vitamin A * Mechanism of action of topical retinoids * Mechanism of action of isotretinoin * Mechanism of action of acitretin * Mechanism of action of bexarotene * Mechanism of action of alitretinoin * Effects of retinoids at the cellular level (differentiation, apoptosis, autophagy, cell cycle regulation, and senescence) * Effects of retinoids at the systemic level * New aspects of isotretinoin teratogenicity * Mucocutaneous side effects * Ophthalmologic side effects * Musculoskeletal side effects * Neurologic side effects * Psychiatric side effects * Gastrointestinal side effects * Endocrine and metabolic side effecs * Other systemic side effects: Cardiovascular, pulmonary, otolaryngorhinologic, genitourinary, renal, and immunologic * Retinoids in acne * Retinoids in hidradenitis suppurativa/acne inversa * Retinoids in rosacea * Retinoids in hair disorders * Retinoids in psoriasis * Retinoids in keratinization disorders * Retinoids in antiaging therapy * Retinoids in other skin diseases * Retinoids in lymphoma * Retinoids in cutaneous chemoprophylaxis * Guide to good clinical practice for vulnerable populations (infancy, childhood, fertile period, elderly) * Retinoids and concomitant surgery * Retinoids and concomitant aesthetic procedures * Laboratory and clinical follow-up * Teratogenicity and registry programs * Management of vitamin A and retinoid side effects * Future and novel unexplored indications of retinoids Published in association with the Journal of Dermatological Treatment.
Author : Maria A Livrea
Publisher : CRC Press
Page : 682 pages
File Size : 32,18 MB
Release : 1993-01-18
Category : Science
ISBN : 9780824787585
This volume contains papers presented at the Conference on Retinoids: New Trends in Research and Clinical Applications, held in 1991 in Palermo, Italy, describing the latest research findings on biochemistry, nutrition, molecular and cell biology and developmental biology, as well as the pharmacology and the therapeutic use of vitamin A and its congeners.;Written by leading authorities in the field from the USA, Europe and Japan, Retinoids, amongst other things: addresses retinol-supported retinoic acid (RA) synthesis and catabolism; identifies synthetic ligands with a high selective affinity for RAR-alpha, -beta and -gamma nuclear receptors, determining if they would show pharmacological properties similar to the natural parent substance all-trans RA; considers the embryonic/foetal cellular retinoid-binding proteins and evidence for their participation in normal and abnormal morphogenesis; discusses a novel arotinoid, Ro 40-8757, that exhibited improved anti-tumour efficacy and safety in pre-clinical tests; and reports the audioradiographic distribution of retinol and RA in organs of pregnant hamsters and foetuses.
Author : Zoe Diana Draelos
Publisher : John Wiley & Sons
Page : 34 pages
File Size : 46,76 MB
Release : 2015-10-14
Category : Medical
ISBN : 111865546X
Back for a new edition, Zoe Draelos' outstanding resource to cosmetic dermatology again provides a highly-illustrated, clinical guide to the full range of cosmetic skin treatments. Bringing together experts from research, industry, surgery and practice, it is structured in four distinct parts for easy navigation by the busy clinician: Basic Concepts - giving an overview of the physiology pertinent to cosmetic dermatology and the delivery systems by which treatments can take effect; Hygiene Products - evaluating cleansing and moisturising products; Adornment - looking at aesthetic techniques such as cosmetics, nail protheses and hair treatment; Antiaging - ie, injectables, resurfacing and skin contouring techniques, and the rapidly growing area of Cosmeceuticals. With over 300 high-quality images and key summary boxes throughout, this new edition incorporates the newest procedural innovations in this rapidly developing field. Perfect for all dermatologists, especially those specialising in cosmetic dermatology and whether hospital-based or in private practice, it provides the complete cosmetic regimen for your patients and will be an indispensable tool to consult over and over again.
Author :
Publisher : ScholarlyEditions
Page : 71 pages
File Size : 25,64 MB
Release : 2012-01-09
Category : Science
ISBN : 1464934983
Retinoids: Advances in Research and Application: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Retinoids in a concise format. The editors have built Retinoids: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Retinoids in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Retinoids: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Author : M.A. Livrea
Publisher : Birkhäuser
Page : 416 pages
File Size : 24,10 MB
Release : 1994-05-26
Category : Medical
ISBN :
Basic investigators as well as clinicians will find this volume valuable both as a summary of recent research and as a stimulus for future experimental work in this continuously expanding field.
Author : Michael B. Sporn
Publisher : Academic Press
Page : 474 pages
File Size : 30,62 MB
Release : 1984-04-28
Category : Medical
ISBN :
Abstract: A 2-volume treatise for scientists and clinicians contains 19 authoritative overview articles by experts in their respective fields, represents the first comprehensive survey of the chemistry and biology of the retinoids. The 2-volume set begins with the basic chemistry concepts of the retinoids (including vitamin A) and their analogs, and progresses towards biological aspects, and then to clinical considerations. Volume 1 deals with new advances in organic and trace chemistry, chemical and biological methods of retinoid analysis and a comprehensive survey of vitamin A in human and animal nutrition. Volume 2 reviews the biochemistry and metabolism of retinoids and retinoid bindingproteins; cellular and molecular mechanisms of action of the retinoids; toxicological, teratological, and immunological aspects; and the applications of retinoids to cancer and dermatology. Chemical structures of the retinoids are appended.(wz).
Author : Lester Packer
Publisher : AOCS Publishing
Page : 350 pages
File Size : 18,6 MB
Release : 2005-05-30
Category : Medical
ISBN : 9781893997837
The presence of carotenoids in the diet and their role in human health has become a subject of unprecedented interest. The chapters in this book represent an account of the information presented at a recent workshop, combined with several additional invited contributions to cover topics more completely that are currently at the cutting edge of research. Some of the highlights of this book include a thorough review of the special role that vitamin A intake plays in the health status of developing countries, the essential role of vitamin A in cell signaling, the molecular targets involved in carotenoid action in smoke-induced lung pathology, and how carotenoids are beneficial in cardiovascular health.
Author : Stephen E. Wolverton
Publisher : Elsevier Health Sciences
Page : 858 pages
File Size : 20,90 MB
Release : 2019-12-14
Category : Medical
ISBN : 0323612121
Designed with practical usability in mind, Comprehensive Dermatologic Drug Therapy, 4th Edition, helps you safely and effectively treat the skin disorders you’re likely to see in your practice. Dr. Stephen E. Wolverton and new associate editor Dr. Jashin J. Wu lead a team of global experts to bring you concise, complete guidance on today's full spectrum of topical, intralesional, and systemic drugs. You’ll prescribe with confidence thanks to expert coverage of which drugs to use, when to use them, and adverse effects to monitor. Includes new drug interaction tables, drug risk profiles, and FDA guidelines, as well as two new appendices that summarize chapter questions and summarize highest-risk drug interactions. Covers the best uses for new biologic therapeutics. Contains new chapters covering medical decision-making principles, PDE-4 and JAK inhibitors, interleukin 17 inhibitors, interleukin 23 inhibitors, additional biologic therapeutics, and hedgehog pathway inhibitors. Contains quick-access summaries of indications/contraindications, dosage guidelines, drug interactions, drug monitoring guidelines, adverse effects, and treatment protocols. Features a highly detailed, disease-specific index, as well as purchase information for major drugs. Helps you assess your knowledge and prepare for certification or recertification with about 800 review questions and answers throughout the book.
Author : Muhammad Zia-Ul-Haq
Publisher : Springer Nature
Page : 862 pages
File Size : 11,41 MB
Release : 2021-02-17
Category : Technology & Engineering
ISBN : 3030464598
Plants produce chemicals as part of their normal metabolic activities. These include primary metabolites found in all plants, such as sugars and fats, as well as secondary metabolites, which can have therapeutic effects in humans and be refined to produce drugs. Plants synthesize a bewildering variety of phytochemicals, but most are derivatives of a few biochemical motifs. Numerous herbal-derived substances have been evaluated for their therapeutic potential. These include alkaloids, coumarins, saponins, plant pigments and flavonoids. Flavonoids, carotenoids and anthocyanins are probably the best known of these substances due to their antioxidant properties. Carotenoids: Structure and Function in the Human Body presents comprehensive coverage of carotenoids. The text covers the scientific literature and clinical significance of this organic pigment, with an emphasis on its therapeutic potential. The authors approach carotenoids from a range of perspectives, from their structural and physicochemical properties to their distribution in nature, interaction with the human metabolism, and use as a coloring agent in various products. The intake, metabolism and secretion of anthocyanins in the human body are covered in-depth, as are the biosynthetic pathways through which these compounds are synthesized in the natural system. Factors affecting stability and extraction are listed, and health-related uses and biological activities are covered in great detail. Present and future trends in carotenoid research are also presented. This book provides a solid background in carotenoids for researchers and professionals in food science, food technology, nutrition, biology, chemistry and medical sciences.
