Robotics for Cell Manipulation and Characterization


Book Description

Robotics for Cell Manipulation and Characterization provides fundamental principles underpinning robotic cell manipulation and characterization, state-of-the-art technical advances in micro/nano robotics, new discoveries of cell biology enabled by robotic systems, and their applications in clinical diagnosis and treatment. This book covers several areas, including robotics, control, computer vision, biomedical engineering and life sciences using understandable figures and tables to enhance readers' comprehension and pinpoint challenges and opportunities for biological and biomedical research. - Focuses on, and comprehensively covers, robotics for cell manipulation and characterization - Highlights recent advances in cell biology and disease treatment enabled by robotic cell manipulation and characterization - Provides insightful outlooks on future challenges and opportunities




Robotic Manipulation of Reproductive Cells


Book Description

This is the first book to focus on robotic reproductive cell manipulation. It provides readers with the fundamental principles underpinning robotic manipulation of reproductive cells, including sperm, oocytes, and embryos, state-of-the-art technical advances in actuation, sensing and control for cell manipulation, and emerging automated systems for reproductive cell manipulation. The methods presented in the book are generic and can be translated to manipulating other types of cells, such as cancer cells and cardiomyocytes. Robotic Manipulation of Reproductive Cells will be an essential reference for graduate students and researchers working on small-scale robotic systems for cell manipulation and characterization, healthcare professionals interested in nanoscale, microscale, milli-scale robotic techniques for clinical cell surgeries and assisted reproduction, and engineers developing small-scale robotic systems for biomedical engineering, biology, and medicine.




Robotic Cell Manipulation


Book Description

Robotic Cell Manipulation introduces up-to-date research to realize this new theme of medical robotics. The book is organized in three levels: operation tools (e.g., optical tweezers, microneedles, dielectrophoresis, electromagnetic devices, and microfluidic chips), manipulation types (e.g., microinjection, transportation, rotation fusion, adhesion, separation, etc.), and potential medical applications (e.g., micro-surgery, biopsy, gene editing, cancer treatment, cell-cell interactions, etc.). The technology involves different fields such as robotics, automation, imaging, microfluidics, mechanics, materials, biology and medical sciences. The book provides systematic knowledge on the subject, covering a wide range of basic concepts, theories, methodology, experiments, case studies and potential medical applications. It will enable readers to promptly conduct a systematic review of research and become an essential reference for many new and experienced researchers entering this unique field. - Introduces the applications of robot-assisted manipulation tools in various cell manipulation tasks - Defines many essential concepts in association with the robotic cell manipulation field, including manipulation strategy and manipulation types - Introduces basic concepts and knowledge on various manipulation devices and tasks - Describes some cutting-edge cell manipulation technologies and case studies




Reproductive Surgery


Book Description

Gain confidence in the surgical management of female and male infertility. Authored by leading experts in operative gynecology and urology, in collaboration with the Society of Reproductive Surgeons, this valuable handbook provides readers with a comprehensive understanding of the indications, techniques, and outcomes of modern reproductive surgery. This manual presents clear step-by-step instructions illustrated with intraoperative photographs and surgical videos in order to offer patients surgical options and avoid, or improve, IVF.




Micromachines for Biological Micromanipulation


Book Description

This book provides an overview of the noteworthy developments in the field of micromachining, with a specific focus on microinjection systems used for biological micromanipulation. The author also explores the design, development, and fabrication of new mechanical designs for micromachines, with plenty of examples that elucidate their modeling and control. The design and fabrication of a piezoelectric microinjector, constant force microinjector, constant force microgripper, PDVF microforce sensor, and a piezoelectric microsyringe are presented as examples of new technology for microinjection systems. This book is appropriate for both researchers and advanced students in bioengineering.




Manual of Intracytoplasmic Sperm Injection in Human Assisted Reproduction


Book Description

"Not everything in medical science has a clear beginning. The first realization of infertility and putative remedies remain shrouded in contextual history, but likely goes back to the dawn of our species, well before there was a written record. Childlessness was, and is still, considered a burden in some communities"--




Aerial Manipulation


Book Description

This text is a thorough treatment of the rapidly growing area of aerial manipulation. It details all the design steps required for the modeling and control of unmanned aerial vehicles (UAV) equipped with robotic manipulators. Starting with the physical basics of rigid-body kinematics, the book gives an in-depth presentation of local and global coordinates, together with the representation of orientation and motion in fixed- and moving-coordinate systems. Coverage of the kinematics and dynamics of unmanned aerial vehicles is developed in a succession of popular UAV configurations for multirotor systems. Such an arrangement, supported by frequent examples and end-of-chapter exercises, leads the reader from simple to more complex UAV configurations. Propulsion-system aerodynamics, essential in UAV design, is analyzed through blade-element and momentum theories, analysis which is followed by a description of drag and ground-aerodynamic effects. The central part of the book is dedicated to aerial-manipulator kinematics, dynamics, and control. Based on foundations laid in the opening chapters, this portion of the book is a structured presentation of Newton–Euler dynamic modeling that results in forward and backward equations in both fixed- and moving-coordinate systems. The Lagrange–Euler approach is applied to expand the model further, providing formalisms to model the variable moment of inertia later used to analyze the dynamics of aerial manipulators in contact with the environment. Using knowledge from sensor data, insights are presented into the ways in which linear, robust, and adaptive control techniques can be applied in aerial manipulation so as to tackle the real-world problems faced by scholars and engineers in the design and implementation of aerial robotics systems. The book is completed by path and trajectory planning with vision-based examples for tracking and manipulation.




Photomedicine in Gynecology and Reproduction


Book Description

The photodynamic technique involves the administration of a photosensitizer followed by application of laser light. When light interacts intracellularly with the photosensitizer, the photon energy absorbed by the sensitizing molecule mainly generates photooxidation for tissue destruction or fluorescence for diagnostics. Photomedical techniques provide a minimally invasive, ambulatory procedure in gynecology, not needing anesthetics. A history of photomedicine explains the main elements and mechanisms of photomedical techniques. One of the main chapters is dedicated to the biochemical and biophysical aspects of photomedicine such as characterization of photosensitizers, their interaction with light, their destruction, the optical dosimetry and optical properties of tissues. The clinical part of this book summarizes the state-of-the-art activity in all major gynecologic applications, from cervix to breast, and provides the reader with an understanding of photodynamic therapy and basic mechanisms. Photon-assisted reproduction, e.g. laser-assisted fertilization, embryo hatching and prenatal diagnosis, makes up the final chapters. Belonging in every hospital or university library, this book underscores why photomedicine appeals to such a broad spectrum of students, basic scientists, clinicians, and members of the corporate world.




A Practical Guide to Setting Up an IVF Lab, Embryo Culture Systems and Running the Unit


Book Description

This book is a complete guide to setting up an IVF laboratory. Beginning with an introduction to the history and the basics, the following chapters take clinicians through the full set up and management process, from air quality control and cryopreservation facilities, to morphological embryo assessment, sperm processing and selection techniques, to document management systems. A separate chapter provides an update on semen analysis based on World Health Organisation (WHO) standards and interpretation of results. Written by an extensive author and editor team from the UK, Europe and the USA, this practical manual is invaluable for embryologists and IVF specialists planning to set up and manage an IVF laboratory successfully. Key points Practical guide to setting up and managing an IVF laboratory Provides step by step process Includes chapter on semen analysis based on WHO standards and interpretation of results Extensive author and editor team from UK, Europe and USA




Single-Cell Omics


Book Description

Single-Cell Omics: Volume 1: Technological Advances and Applications provides the latest technological developments and applications of single-cell technologies in the field of biomedicine. In the current era of precision medicine, the single-cell omics technology is highly promising due to its potential in diagnosis, prognosis and therapeutics. Sections in the book cover single-cell omics research and applications, diverse technologies applied in the topic, such as pangenomics, metabolomics, and multi-omics of single cells, data analysis, and several applications of single-cell omics within the biomedical field, for example in cancer, metabolic and neuro diseases, immunology, pharmacogenomics, personalized medicine and reproductive health. This book is a valuable source for bioinformaticians, molecular diagnostic researchers, clinicians and members of the biomedical field who are interested in understanding more about single-cell omics and its potential for research and diagnosis. - Covers not only the technological aspects, but also the diverse applications of single cell omics in the biomedical field - Summarizes the latest progress in single cell omics and discusses potential future developments for research and diagnosis - Written by experts across the world, bringing different points-of-view and case studies to give a comprehensive overview on the topic