Salmonella Mutagenicity Tests: II
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Publisher :
Page : 119 pages
File Size : 27,86 MB
Release : 1986
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ISBN :
Author :
Publisher :
Page : 119 pages
File Size : 27,86 MB
Release : 1986
Category :
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Author : Ludwig Hothorn
Publisher : Springer Science & Business Media
Page : 158 pages
File Size : 24,40 MB
Release : 2013-03-08
Category : Medical
ISBN : 364248736X
This book contains selected papers from a workshop on modern statistical methods in toxicology held during the EUROTOX '90 conference in Leipzig. The papers deal with the biostatistical evaluation of the commonly used toxicological assays, i.e. mutagenicity, long-term carcinogenicity, embryotoxicity and chronic toxicity assays. The biological background is considered in detail, and most of the related statistical approaches described. In five overview papers, the present state of the art of the related topics is given, while in several contributed papers new approaches are discussed. The most important features are: - A new view on the per-litter analysis problem in em- bryotoxicity assays. - A highly sophisticated treatment of the so-called muta-tox problem in mutagenicity assays. - A detailed discussion of the multiplicity problem based on the closed testing procedure. This volume provides readers with an overview of modern biostatistical methods for several toxicological assays and is in part intended for direct, practical use.
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Page : pages
File Size : 31,86 MB
Release : 1987
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Page : pages
File Size : 24,54 MB
Release : 1988
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Author : Errol Zeiger
Publisher :
Page : 158 pages
File Size : 15,8 MB
Release : 1992
Category : Chemical mutagenesis
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Author : Kristien Mortelmans
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Page : pages
File Size : 17,22 MB
Release : 1986
Category : Mutagenicity testing
ISBN :
Author : Errol Zeiger
Publisher :
Page : 158 pages
File Size : 18,66 MB
Release : 1988
Category : Chemical mutagenesis
ISBN :
Author : Errol Zeiger
Publisher :
Page : 109 pages
File Size : 40,72 MB
Release : 1987
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Page : pages
File Size : 21,62 MB
Release : 1992
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Author : Ashutosh Kumar
Publisher : Academic Press
Page : 352 pages
File Size : 38,42 MB
Release : 2017-09-26
Category : Science
ISBN : 0128092602
Mutagenicity: Assays and Applications presents an extensive examination of the detection, assessment and future of mutagenicity, particularly as it concerns human health and the environment. Chapters focused on specific types of mutagens or testing methods for their detection collectively explore the current state of human and environmental mutagenesis, future perspectives and regulatory needs. The test procedures for measuring mutagenicity, their advantages and limitations are described with practical and procedural detail, along with their presentation and data processing aspects. It is an essential reference covering the breadth and depth of the field of mutagenicity studies and regulation. By providing both important introductory material and practical assays and applications, this book is useful to graduate students, academic and industry researchers and regulators at various stages of their careers, leading to improved risk assessment and regulation. - Presents an up-to-date and in-depth review of the current state of mutagenesis research - Draws upon the combined experience and expertise of an international group of highly respected editors and chapter authors - Provides an introduction to the concept of mutagenesis with particular consideration given to novel chemicals and materials