Primary Immunodeficiencies Worldwide
Author : Menno C. van Zelm
Publisher : Frontiers Media SA
Page : 224 pages
File Size : 42,81 MB
Release : 2020-02-19
Category :
ISBN : 2889635201
Author : Menno C. van Zelm
Publisher : Frontiers Media SA
Page : 224 pages
File Size : 42,81 MB
Release : 2020-02-19
Category :
ISBN : 2889635201
Author : Kathleen E. Sullivan
Publisher : Academic Press
Page : 1334 pages
File Size : 28,66 MB
Release : 2020-05-23
Category : Medical
ISBN : 0128172959
Stiehm's Immune Deficiencies: Inborn Errors in Immunity, Second Edition, is ideal for physicians and other caregivers who specialize in immunology, allergies, infectious diseases and pulmonary medicine. It provides a validated source of information for care delivery to patients, covering approaches to diagnosis that use both new genetic information and emphasize screening strategies. Management has changed dramatically over the past five years, so approaches to infection and autoimmunity are emphasized in an effort to improve outcomes and disseminate new information on the uses of targeted therapy. - Covers immune deficiencies that are presented in a practical way, providing helpful information for active clinicians - Fills an increasingly deep gap in the information available to clinicians - Presents both clinical management and scientific advances for immune deficiencies - Provides a primary resource for physicians in the field of immunodeficiencies - Includes website access to a range of videos relevant to the topics discussed
Author : Jonathan A. Bernstein
Publisher : Springer Nature
Page : 409 pages
File Size : 16,78 MB
Release : 2021-01-28
Category : Medical
ISBN : 3030571572
This book provides a broad clinical overview of primary and secondary immunodeficiencies nested in clinical cases that will help the reader understand the approach to evaluation, diagnosis, and management of these challenging cases. Chapters begin with a comprehensive overview of immunodeficiencies to ground the reader in practical knowledge of the field and these complex conditions. Chapters cover B lymphocyte immunodeficiency, T cell immunodeficiency, immune dysregulation syndromes, and innate immune defects. They discuss a range of treatment options including gene therapy or bone marrow transplant. The book continues with a discussion on secondary immunodeficiencies and their treatment. Each chapter was written by authors with expertise related to different immunodeficiency disorders and provide a succinct overview of pathomechanisms, diagnosis, and treatment of a specific condition. Primary and Secondary Immunodeficiency will be an excellent resource for practicing allergists, hematologists, clinical immunologists, fellows, residents, and other clinicians who work with immunodeficiency patients.
Author : Amos Etzioni
Publisher : Academic Press
Page : 377 pages
File Size : 46,58 MB
Release : 2014-09-13
Category : Medical
ISBN : 0124115543
Primary Immunodeficiency Disorders: A Historic and Scientific Perspective provides a complete historical context that is crucial for students and researchers concerned with primary immunodeficiency. When researchers have a poor understanding of the way we arrived where we are in research, they can miss important points about a disease, or miss out on how to approach new diseases. This historical knowledge of research can assist greatly by showing how it was done in the past, demonstrating the successes and failures, so that it can be done better in the future. This book provides an understanding of the process going from clinical problem to lab and back to the clinic, based on historical experiences. Its chapters proceed from the discovery of the T and B cell lineages through the first BMT for immunodeficiency disorder; lab investigation and gene therapy for PID; the discovery of the gene for AT and its function; understanding cytokine defects; and many other stops along the way. - Facilitates communication among physicians and other investigators concerned with immunological and inflammatory diseases - Summarizes for the first time all the known facts from 60 years of primary immunodeficiency research, and teaches how an important field in medicine was established - Provides stimulating discussions on developing new medical therapiesHighlights the importance of studying humans to understand mechanisms of disease that affect humans
Author : Hans D. Ochs
Publisher :
Page : 745 pages
File Size : 31,54 MB
Release : 2007
Category : Medical
ISBN : 019514774X
The second edition of Primary Immunodeficiency Diseases presents discussions of gene identification, mutation detection, and clinical and research applications for over 100 genetic immune disorders--disorders featuring an increased susceptibility to infections and, in certain conditions, an icreased rate of malignancies and autoimmune disorders. Since the publication of the first edition, a flurry of new disease entities has been defined and new treatment regimens have been introduced, the most spectacular being successful treatment by gene therapy for two genotypes of combined immunodeficiency. The first edition marked a historic turning point in the field of immunodeficiencies, demonstrating that many of the disorders of the immune systam could be understood at a molecular level. This new edition can proudly document the tremendous pace of progress in dissecting the complex immunologic networks responsible for protecting individuals from these disorders.
Author : Nima Rezaei
Publisher : Springer
Page : 593 pages
File Size : 38,13 MB
Release : 2016-11-30
Category : Medical
ISBN : 3662529092
The number of diagnosed cases of primary immunodeficiency diseases (PIDs) – a group of inborn disorders of the immune system – is growing rapidly, but misdiagnosis or late diagnosis still occurs in a significant number of patients, with serious consequences. This is the second edition of a practical reference textbook on PIDs that has been widely welcomed by scientists and clinicians from around the world. The new edition has been extensively revised to reflect advances in knowledge and includes various PIDs not previously covered. For each disease, information is provided on definition, etiology, clinical manifestations, diagnosis, and management. This book will represent an ideal resource for specialists when engaging in diagnosis, clinical decision-making, and treatment planning. It will also prove invaluable for doctors in training and other physicians and nurses who wish to learn more about PIDs.
Author : John P. Sundberg
Publisher : CRC Press
Page : 582 pages
File Size : 46,40 MB
Release : 1994-05-19
Category : Medical
ISBN : 9780849383724
Handbook of Mouse Mutations with Skin and Hair Abnormalities presents 48 mouse mutations that are all available to the biomedical community. Many of the mouse mutations with dermatological diseases are reviewed and illustrated in detail. This popular reference book gives you a single source to use when determining which mouse mutation will best serve your needs as a biomedical tool for sophisticated research projects. The book also includes an overview of domestic animal genodermatoses to provide alternatives to mouse models that do not exist or to complement those that do. A detailed section written by renowned experts compares the biology of human and mouse skin and skin diseases in the areas of development and the use of animal models, mammalian genetics, keratin biochemistry, epidermal and hair follicle cycles and kinetics, cytokines and growth factors, keratinocyte culture systems, cutaneous carcinogenesis, cutaneous immune system, and skin changes associated with mutations of the endocrine system.
Author : Asghar Aghamohammadi
Publisher : Academic Press
Page : 396 pages
File Size : 32,35 MB
Release : 2021-01-22
Category : Medical
ISBN : 0128231890
Awareness among clinicians about PIDs, which consist of more than 400 different entities, plays an important role in ensuring that patients receive a timely diagnosis. Furthermore, clinicians who are educated about PIDs can give their patients access to optimal management of their condition, thus helping the patient achieve a better quality-of-life and long-term prognosis. Inborn Errors of Immunity: A Practical Guide provides the most up-to-date information for busy students, nurses, clinical residents, practicing physicians, and even basic researchers. Readers will benefit from a well-structured breakdown of complicated PID diseases, including approaches to their clinical signs/symptoms and immunologic/laboratory findings. - Presents valuable contribution of more than 40 expert chapter authors, from top centers spanning five continents, each in a specific PID field - Covers various aspects of PID using updated clinical guidelines and standard stepwise pipelines - Focuses on the latest developments in the molecular diagnosis and pathogenesis of diseases, with easy explanation and schematic representation of defective signaling pathways - Includes dedicated sections for clinical features and immunological tests with carefully-curated figures of PID manifestations, imaging, and histological/pathological illustrations to create the first PID medial-color atlas - Summarizes the updated conventional and specific treatments and follow-up notes for different PID diseases
Author : Nicola Yoon
Publisher : Delacorte Press
Page : 322 pages
File Size : 32,77 MB
Release : 2015-09-01
Category : Young Adult Fiction
ISBN : 0553496662
Risk everything for love with this #1 New York Times bestseller from Nicola Yoon • "Gorgeous and lyrical"—The New York Times Book Review What if you couldn’t touch anything in the outside world? Never breathe in the fresh air, feel the sun warm your face . . . or kiss the boy next door? In Everything, Everything, Maddy is a girl who’s literally allergic to the outside world, and Olly is the boy who moves in next door . . . and becomes the greatest risk she’s ever taken. "This extraordinary first novel about love so strong it might kill us is too good to feel like a debut. Tender, creative, beautifully written, and with a great twist, Everything, Everything is one of the best books I've read this year."—Jodi Picoult My disease is as rare as it is famous. Basically, I’m allergic to the world. I don’t leave my house, have not left my house in seventeen years. The only people I ever see are my mom and my nurse, Carla. But then one day, a moving truck arrives next door. I look out my window, and I see him. He's tall, lean and wearing all black—black T-shirt, black jeans, black sneakers, and a black knit cap that covers his hair completely. He catches me looking and stares at me. I stare right back. His name is Olly. Maybe we can’t predict the future, but we can predict some things. For example, I am certainly going to fall in love with Olly. It’s almost certainly going to be a disaster. Everything, Everything will make you laugh, cry, and feel everything in between. It's an innovative, inspiring, and heartbreakingly romantic debut novel that unfolds via vignettes, diary entries, illustrations, and more. And don’t miss Nicola Yoon's bestselling novels The Sun Is Also A Star and Instructions for Dancing.
Author : Aisha Chaudhary
Publisher : Bloomsbury Publishing
Page : 62 pages
File Size : 37,12 MB
Release : 2017-01-06
Category : Reference
ISBN : 9386250985
This is a movie tie-in edition and any reviews posted before October 10, 2019 are from the previous edition of the same title published in 2015. Aisha Chaudhary was born with SCID (severe combined immune deficiency) and underwent a bone-marrow transplant when she was six months old. She lived in New Delhi, where she was born. The year 2014 was brutal for Aisha as her disease progressed, and her lungs started giving up on her. The last few months of the year felt like a roller-coaster ride, one that seemed to be mostly going down. Spending almost all her time lying in bed, Aisha wrote down her thoughts to get some relief, to get them out of her head. Aisha's life was not anything like the average life of an urban teenager, but she had experienced a lifetime of emotions; life and death, fear and anger, love and hate, the depths of utter sorrow and the happiest one can be. In My Little Epiphanies she took a hard look at her own feelings and what it was that gave her a sense of hope and control. This book gave her life purpose and meaning, something to hold on to. Sometimes, Aisha's little epiphanies had morphed into doodles that capture what was going on in her mind as her destiny played itself out. Through the book she wanted the world to understand her unusual life and she hoped that it will inspire others, going through similar hardships, to find peace.