Synthesis of Best-Seller Drugs


Book Description

Synthesis of Best-Seller Drugs is a key reference guide for all those involved with the design, development, and use of the best-selling drugs. Designed for ease of use, this book provides detailed information on the most popular drugs, using a practical layout arranged according to drug type. Each chapter reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and synthesis. Of high interest to all those who work in the captivating areas of biologically active compounds and medicinal drug synthesis, in particular medicinal chemists, biochemists, and pharmacologists, the book aims to support current research efforts, while also encouraging future developments in this important field. - Describes methods of synthesis, bioactivity and related drugs in key therapeutic areas - Reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and more - Presents a practical layout designed for use as a quick reference tool by those working in drug design, development and implementation




Sildenafil


Book Description

Sildenafil, for the treatment of erectile dysfunction, is one of the first products that has made its way successfully from basic NO (nitrous oxide) research, to clinical routine therapy. Sidenafil, part of the Milestones in Drug Therapy series, presents the major breakthroughs in the field of NO physiology and pharmacology that led to the development of the drug, as well as clinical applications in one source guide. Written by leading experts in the field, each chapter covers aspects of clinical use and experience, pharmacokinetics, pharmacodynamics, biochemistry, and cultural science.




Viagra (sildenafil Citrate)


Book Description




Davis's Drug Guide for Rehabilitation Professionals


Book Description

A one-of-a-kind guide specifically for rehabilitation specialists! A leader in pharmacology and rehabilitation, Charles Ciccone, PT, PhD offers a concise, easy-to-access resource that delivers the drug information rehabilitation specialists need to know. Organized alphabetically by generic name, over 800 drug monographs offer the most up-to-date information on drug indications, therapeutic effects, potential adverse reactions, and much more! A list of implications for physical therapy at the end of each monograph helps you provide the best possible care for your patients. It’s the perfect companion to Pharmacology in Rehabilitation, 4th Edition!







Analytical Profiles of Drug Substances and Excipients


Book Description

Although the official compendia define a drug substance as to identity, purity, strength, and quality, they normally do not provide other physical or chemical data, nor do they list methods of synthesis or pathways of physical or biological degradation and metabolism. Such information is scattered throughout the scientific literature and the files of pharmaceutical laboratories. Edited by the Associate Director of Analytical Research and Development for the AmericanAssociation of Pharmaceutical Scientists, Analytical Profiles of Drug Substances and Excipients brings this information together into one source. The scope of the series has recently been expanded to include profiles of excipient materials.




Disposition of Toxic Drugs and Chemicals in Man


Book Description

Discussions include occurrence and usage, blood concentrations, metabolism and excretion, toxicity, analysis and bibliographic references.




Surgery for Congenital Heart Defects


Book Description

Over 10 years after the publication of the second edition, Wiley now publishes the third edition of the popular volume Surgery for Congenital Heart Defects. Completely updated and expanded, this new edition describes step-by-step the surgical procedures for congenital heart defects and includes detailed illustrations for each operation. New in this edition are chapters on exercise testing, MRI, EP studies and catheter ablation of arrhythmias, extracorporeal circulatory support and paediatric lung transplantation. A greatly expanded ultrasound chapter contains numerous colour Doppler’s of many conditions. Surgery for Congenital Heart Defects, Third Edition: Provides complete coverage of the current issues in paediatric cardiac surgery Offers tips and surgical techniques to master difficult surgical situations Uniquely displays detailed illustrations for each operation, allowing surgeons to follow all operating procedures step-by-step Serves both as reference and training manual




The Essential Guide to Sildenafil


Book Description

Discover a wealth of important information about the drug, sildenafil inside my book, The Essential Guide to Sildenafil: Usage, Precautions, Interactions and Side Effects. A must-read book to learn about the conditions that sildenafil is used to treat through to the range of potentially life-threatening side effects and drug interactions that can occur while taking this commonly prescribed medication. Inside my new book you will discover: Sildenafil Brand Names. A comprehensive listing of sildenafil brand name medications in the United States, Canada and Europe, never be unsure about the medications you are taking again by being able to identify what brand name medications contain sildenafil. Medical Conditions Sildenafil Treats. Discover the wide range of conditions that a course of sildenafil can treat, cure and prevent. Know what your doctor or medical professional may prescribe for certain conditions before going into the doctor’s office. Risks of Taking Sildenafil. As with all medications there are some inherent risks when taking sildenafil, learn what these risks are, how to identify them with your medical professional or doctor and what signs to look for in case of an emergency. Sildenafil Side Effects & Interactions. From drug interactions, allergies and more, discover the variety of interactions that you need to know about before starting a prescribed course of sildenafil medications and what to do if a reaction should occur during or after completing your prescribed course of sildenafil. Plus, so much more... Start reading my book right now and arm yourself with the information you need to make an educated decision when weighing the risks and benefits of taking the common prescription drug, sildenafil.




Essential Pharmacokinetics


Book Description

Essential Pharmacokinetics: A Primer for Pharmaceutical Scientists is an introduction to the concepts of pharmacokinetics intended for graduate students and new researchers working in the pharmaceutical sciences. This book describes the mathematics used in the mammillary model as well as the application of pharmacokinetics to pharmaceutical product development, and is useful as both a self-study and classroom resource. Content coverage includes detailed discussions of common models and important pharmacokinetic concepts such as biological half-life, clearance, excretion, multiple dosage regimens and more. Numerous equations, practical examples and figures are incorporated to clearly illustrate the theoretical background of pharmacokinetic behavior of drugs and excipients. - Shows how to apply basic pharmacokinetic methods to evaluate drugs, excipients and drug products - Uses guided practice questions, mathematical concepts and real-world examples for self-assessment and retention purposes - Illustrates how to write and evaluate drug registration files