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Sleep-Wake Neurobiology and Pharmacology

Author : Hans-Peter Landolt

Publisher : Springer Nature

Page : 473 pages

File Size : 14,17 MB

Release : 2019-09-03

Category : Medical

ISBN : 3030112721

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Book Description

This volume connects current ideas and concepts about sleep functions and circadian rhythms with the search for novel target-selective sleep-wake therapeutics. To do so, it provides a timely, state-of-the-art overview of sleep-wake mechanisms in health and disease, ongoing developments in drug discovery, and their prospects for the clinical treatment of sleep-disordered patients. It particularly focuses on the concept that sleep and wakefulness mutually affect each other, and the future therapeutic interventions with either sleep- or wake-promoting agents that are expected to not only improve the quality of sleep but also the waking behavior, cognition, mood and other sleep-associated physiological functions. The chapter 'Sleep Physiology, Circadian Rhythms, Waking Performance and the Development of Sleep-Wake Therapeutics' available open access under a CC BY 4.0 license at link.springer.com



Foundations of Psychiatric Sleep Medicine

Author : John W. Winkelman

Publisher : Cambridge University Press

Page : 435 pages

File Size : 16,72 MB

Release : 2010-12-23

Category : Medical

ISBN : 1139494341

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Book Description

Sleep-related complaints are extremely common across the spectrum of psychiatric illness. Accurate diagnosis and management of sleep disturbances requires an understanding of the neurobiological mechanisms underlying sleep and wakefulness, the characteristics of sleep disturbance inherent to psychiatric illness and primary sleep disorders, as well as the psychopharmacologic and behavioral treatments available. Foundations of Psychiatric Sleep Medicine provides a uniquely accessible, practical, and expert summary of current clinical concepts at the sleep-psychiatry interface. Topics covered include: basic principles in sleep science, clinical sleep history taking, primary sleep disorders in psychiatric contexts, and sleep disturbance across a range of mood, anxiety, psychotic, substance use, cognitive and developmental disorders. Written by outstanding experts in the field of sleep medicine and psychiatry, this academically rigorous and clinically useful text is an essential resource for psychiatrists, psychologists and other health professionals interested in the relationship between sleep and mental illness.



Anesthetic Pharmacology

Author : Alex S. Evers

Publisher : Cambridge University Press

Page : 2902 pages

File Size : 21,68 MB

Release : 2011-03-10

Category : Medical

ISBN : 1139497022

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Book Description

In recent years our understanding of molecular mechanisms of drug action and interindividual variability in drug response has grown enormously. Meanwhile, the practice of anesthesiology has expanded to the preoperative environment and numerous locations outside the OR. Anesthetic Pharmacology: Basic Principles and Clinical Practice, 2nd edition, is an outstanding therapeutic resource in anesthesia and critical care: Section 1 introduces the principles of drug action, Section 2 presents the molecular, cellular and integrated physiology of the target organ/functional system and Section 3 reviews the pharmacology and toxicology of anesthetic drugs. The new Section 4, Therapeutics of Clinical Practice, provides integrated and comparative pharmacology and the practical application of drugs in daily clinical practice. Edited by three highly acclaimed academic anesthetic pharmacologists, with contributions from an international team of experts, and illustrated in full colour, this is a sophisticated, user-friendly resource for all practitioners providing care in the perioperative period.



The Orexin System. Basic Science and Role in Sleep Pathology

Author : M.A. Steiner

Publisher : Karger Medical and Scientific Publishers

Page : 165 pages

File Size : 42,6 MB

Release : 2021-05-28

Category : Health & Fitness

ISBN : 3318068446

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Book Description

The orexin system, discovered in 1998, has emerged as a crucial player in regulating the sleep and wake balance inside our brain. This discovery has sparked a burst of novel and dynamic research on the physiology and pathology of sleep. The Orexin System: Basic Science and Role in Sleep Pathology honors this research and the authors share their ideas and perspectives on the novel developments within the field. The book examines the intricate role of the orexin system in regulating sleep and wake, and its interaction with other wake-regulating systems. The orexin system is dissected at the cellular and molecular level to explore the diversity of the orexin-producing neurons, their projections, and their signaling pathways. Additionally, the book discusses the diseases which are associated with a dysfunctional orexin system, such as narcolepsy, insomnia, substance abuse, and Alzheimer’s disease, and explores the new potential therapeutic applications derived from the burst of research around this fascinating system. This publication is essential reading for neurobiologists, neurologists, psychopharmacologists, sleep researchers, and other researchers and clinical scientists interested in sleep, sleep research, insomnia, and medicine in general.



Sleep Disorders in Neurology

Author : Sebastiaan Overeem

Publisher : John Wiley & Sons

Page : 344 pages

File Size : 33,44 MB

Release : 2010-03-26

Category : Health & Fitness

ISBN : 9781444315165

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Book Description

Formulate treatment plans with confidence when you consult SleepDisorders in Neurology, a helpful overview of both common andrare neurological disorders that are frequently accompanied bysignificant sleep disturbances. This concise guide explains when toconsult a sleep specialist in managing a particular sleep disorderand draws on the expertise of neurologists who specialize in thedisorders under discussion. This practical guide is fullyillustrated and easily digested, providing a counterpoint to largeencyclopedic reference volumes. The authors take you from historytaking and diagnostic testing, to pharmacological andnon-pharmacological treatment options, and are joined by diseasesub-specialists in the chapters on disease specific sleepdisturbances and the effects of common neurological medications onsleep. This book is essential for sleep medicine specialists, as wellas for clinicians and health care professionals not specificallytrained in sleep medicine, but who nevertheless need to manageneurologically damaged patients with increasingly recognizedsleep-wake disturbances.



Sleep Disorders (Oxford Psychiatry Library)

Author : Sue Wilson

Publisher : Oxford University Press

Page : 119 pages

File Size : 36,1 MB

Release : 2013-09-26

Category : Medical

ISBN : 0199674558

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Book Description

This pocketbook provides provide general psychiatrists and trainees with an updated text on the management of sleep disorders.



Sleep Disorders and Sleep Deprivation

Author : Institute of Medicine

Publisher : National Academies Press

Page : 425 pages

File Size : 25,20 MB

Release : 2006-10-13

Category : Medical

ISBN : 0309101115

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Book Description

Clinical practice related to sleep problems and sleep disorders has been expanding rapidly in the last few years, but scientific research is not keeping pace. Sleep apnea, insomnia, and restless legs syndrome are three examples of very common disorders for which we have little biological information. This new book cuts across a variety of medical disciplines such as neurology, pulmonology, pediatrics, internal medicine, psychiatry, psychology, otolaryngology, and nursing, as well as other medical practices with an interest in the management of sleep pathology. This area of research is not limited to very young and old patientsâ€"sleep disorders reach across all ages and ethnicities. Sleep Disorders and Sleep Deprivation presents a structured analysis that explores the following: Improving awareness among the general public and health care professionals. Increasing investment in interdisciplinary somnology and sleep medicine research training and mentoring activities. Validating and developing new and existing technologies for diagnosis and treatment. This book will be of interest to those looking to learn more about the enormous public health burden of sleep disorders and sleep deprivation and the strikingly limited capacity of the health care enterprise to identify and treat the majority of individuals suffering from sleep problems.



The Pharmacology of Sleep

Author : Anthony Kales

Publisher : Springer Science & Business Media

Page : 603 pages

File Size : 12,78 MB

Release : 2012-12-06

Category : Medical

ISBN : 3642578365

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Book Description

A review of the current state of the clinical and basic science of the pharmacology of sleep. The information provided ranges from a historical perspective to current concepts of sleep mechanisms, including the interaction between pharmacology and sleep-wake regulation and between chronopahrmacology and sleep-wake rhythms. For the first time in one single volume, both the basic mechanisms of sleep, and the basic and clinical aspects of the pharmacology of sleep are dealt with in a thorough, comprehensive and authoritative manner. The chapters, written by the foremost scientific authorities in this field, integrate the latest information on the basic mechanisms of drugs as they relate to their effects on sleep.



Neurochemistry of Sleep and Wakefulness

Author : Jaime Monti

Publisher : Cambridge University Press

Page : 506 pages

File Size : 49,51 MB

Release : 2008-01-17

Category : Medical

ISBN : 9780521864411

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Book Description

Pharmacological approaches to our understanding of sleep have been at the forefront of sleep research for many years. Traditional techniques have included the use of pharmacological agonists and antagonists, as well as transmitter-specific lesions. These have been enhanced by the introduction of molecular genetics and the use of transgenes and targeted gene deletion. Neurochemistry of Sleep and Wakefulness is an exceptional, single source of information on the role of the major mammalian neurotransmitter systems involved in the regulation of sleep and waking. With contributions from internationally recognized experts, this book clearly describes how researchers have made use of the myriad techniques in their armamentarium to characterize the role of a given neurotransmitter in the regulation of sleep and waking. Suitable for experimental and clinical pharmacologists, the book will have wider appeal to sleep researchers, psychiatrists and any professional interested in the interdisciplinary areas of neurobiology and pharmacology.



Sleep Disorders Medicine

Author : Sudhansu Chokroverty

Publisher : Saunders

Page : 710 pages

File Size : 46,36 MB

Release : 2009

Category : Health & Fitness

ISBN :

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Book Description

Dr. Sudhansu Chokroverty-a world-recognized expert in sleep medicine-presents the third edition of Sleep Disorders Medicine for the latest developments in this rapidly expanding specialty, with coverage of neuroscience and clinical application. In addition to summarizing basic science and important technological aspects of diagnosis and treatment, this edition presents new chapters-on sleep and memory consolidation, neuroimaging, and more-in a color layout that makes it easy to access the latest advances in the field. The text's manageable size and logical, multi-disciplinary approach make it the right choice for newcomers and experienced clinicians alike. Covers all aspects of sleep medicine in a practical, logical format divided into three sections: the basic science of sleep physiology, neuroanatomy, and biochemistry; the technical methods of recording; and a clinical approach to patients with sleep complaints. Represents the breadth of knowledge across disciplines through the contributions of 50 prominent names in the field of sleep medicine. Provides a multidisciplinary approach to the diagnosis and management of sleep disorders with coverage of related fields such as pulmonology, otolaryngology, and psychiatry. Includes a Glossary of Terms adapted from the American Sleep Disorders Association for quick reference to the sleep terminology used throughout the text. Offers online access to the full text through Expert Consult functionality for convenient reference. Demonstrates how recent basic science advances affect clinical medicine through new chapters on Sleep Deprivation and Sleepiness; Sleep and Memory Consolidation; Neuroimaging in Sleep and Sleep Disorders; Nutrition and Sleep; Nature and Treatment of Insomnia; Evolution of Sleep from Birth through Adolescence; Sleep-Disordered Breathing in Children and Women's Sleep. Improves on the clarity and consistency of the text with a new, completely redrawn art program, including full-color illustrations in the clinical section that enhances diagnostic material. Presents the material in an even more readable and user-friendly two-color design and page layout.