Functional Cerebral SPECT and PET Imaging


Book Description

This Fourth Edition reflects the significant recent progress that has occurred in functional brain imaging, particularly the increased use of PET/SPECT, the use of SPECT and PET in movement disorders and dementia, and advances in radiopharmaceutical development and instrumentation. Chapter topics include PET physics and instrumentation, PET radiopharmaceuticals, SPECT radiopharmaceuticals, and technical factors. The entire book has been thoroughly revised to reflect an appropriate balance between SPECT and PET applications. Highlights of this edition include a new chapter on neuroreceptor imaging and kinetic modeling, a new chapter on brain imaging in movement disorders, and significant updates on SPECT radiopharmaceuticals.




SPECT Imaging of the Brain


Book Description

In the developed world, images of brain structure are available as an everyday diagnostic aid, and the characteristic appearances of most pathological conditions can be looked up in a textbook. Functional brain imaging is to this day less widely used, partly because most pressing diagnostic questions can be answered by refer ence to the patient's cerebral anatomy, partly for reasons of technical limitations of functional techniques. PET as a technique is sufficiently resource-demanding and complex to inhibit its use as an everyday diagnostic technique. SPECT lacked suitable tracers for many years, and early systems had poor spatial resolution. However, rotating gamma camera technology has advanced to the point where images of the brain of reasonable quality can be obtained at most large hospitals, and practical tracers, particularly of regional cerebral blood flow, are easily avail able. As research advances, clinical applications are emerging. A recent report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology! details a number of currently recognised clinical appli cations, some of which are dealt with in this book. Given this recognition, it is increasingly important that clinicians (particularly neuroclinicians, psychiatrists and specialists in cerebrovascular disease), nuclear medicine specialists and physicists acquire an idea of the major applications of the technique, and the research background on which these applications are based.




PET and SPECT in Neurology


Book Description

PET and SPECT in Neurology highlight the combined expertise of renowned authors whose dedication to the investigation of neurological disorders through nuclear medicine technology has achieved international recognition. Classical neurodegenerative disorders are discussed as well as cerebrovascular disorders, brain tumors, epilepsy, head trauma, coma, sleeping disorders and inflammatory and infectious diseases of the CNS. The latest results in nuclear brain imaging are detailed. Most chapters are written jointly by a clinical neurologist and a nuclear medicine specialist to ensure a multidisciplinary approach. This state-of-the-art compendium will be valuable not only to neurologists and radiologists/nuclear medicine specialists but also to interested general practitioners and geriatricians. It is the second volume of a trilogy on PET and SPECT imaging in the neurosciences, the other volumes covering PET and SPECT in psychiatry and in neurobiological systems.




Imaging of the Human Brain in Health and Disease


Book Description

Brain imaging technology remains at the forefront of advances in both our understanding of the brain and our ability to diagnose and treat brain disease and disorders. Imaging of the Human Brain in Health and Disease examines the localization of neurotransmitter receptors in the nervous system of normal, healthy humans and compares that with humans who are suffering from various neurologic diseases. Opening chapters introduce the basic science of imaging neurotransmitters, including sigma, acetylcholine, opioid, and dopamine receptors. Imaging the healthy and diseased brain includes brain imaging of anger, pain, autism, the release of dopamine, the impact of cannabinoids, and Alzheimer's disease. This book is a valuable companion to a wide range of scholars, students, and researchers in neuroscience, clinical neurology, and psychiatry, and provides a detailed introduction to the application of advanced imaging to the treatment of brain disorders and disease. - A focused introduction to imaging healthy and diseased brains - Focuses on the primary neurotransmitter release - Includes sigma, acetylcholine, opioid, and dopamine receptors - Presents the imaging of healthy and diseased brains via anger, pain, autism, and Alzheimer's disease




You, Happier


Book Description

#1 New York Times bestselling author Dr. Daniel Amen reveals the seven neuroscience secrets to becoming more than 30 percent happier in just 30 days—regardless of your age, upbringing, genetics, or current situation. Happiness is a brain function. With a healthier brain always comes a happier life. After studying more than 200,000 brain scans of people from 155 countries, Dr. Amen has discovered five primary brain types and seven neuroscience secrets that influence happiness. In You, Happier, he explains them and offers practical, science-based strategies for optimizing your happiness. Dr. Amen will teach you how to discover your brain type based on your personality and create happiness strategies best suited to you; improve your overall brain health to consistently enhance your mood; protect your happiness by distancing yourself from the “noise” in your head; and make seven simple decisions and ask seven daily questions to enhance your happiness. Creating consistent happiness is a daily journey. In You, Happier, Dr. Amen walks you through neuroscience-based habits, rituals, and choices that will boost your mood and help you live each day with clearly defined values, purpose, and goals.




Handbook of Particle Detection and Imaging


Book Description

The handbook centers on detection techniques in the field of particle physics, medical imaging and related subjects. It is structured into three parts. The first one is dealing with basic ideas of particle detectors, followed by applications of these devices in high energy physics and other fields. In the last part the large field of medical imaging using similar detection techniques is described. The different chapters of the book are written by world experts in their field. Clear instructions on the detection techniques and principles in terms of relevant operation parameters for scientists and graduate students are given.Detailed tables and diagrams will make this a very useful handbook for the application of these techniques in many different fields like physics, medicine, biology and other areas of natural science.




Images of Human Behavior


Book Description

An introduction to brain SPECT imaging and brain-behavior relationships. Contains images on a wide variety of neuropsychiatric disorders, including dementia, brain trauma, depression, anxiety, ADD, PMS, aggression, and drug abuse.




Emission Tomography


Book Description

PET and SPECT are two of today's most important medical-imaging methods, providing images that reveal subtle information about physiological processes in humans and animals. Emission Tomography: The Fundamentals of PET and SPECT explains the physics and engineering principles of these important functional-imaging methods. The technology of emission tomography is covered in detail, including historical origins, scientific and mathematical foundations, imaging systems and their components, image reconstruction and analysis, simulation techniques, and clinical and laboratory applications. The book describes the state of the art of emission tomography, including all facets of conventional SPECT and PET, as well as contemporary topics such as iterative image reconstruction, small-animal imaging, and PET/CT systems. This book is intended as a textbook and reference resource for graduate students, researchers, medical physicists, biomedical engineers, and professional engineers and physicists in the medical-imaging industry. Thorough tutorials of fundamental and advanced topics are presented by dozens of the leading researchers in PET and SPECT. SPECT has long been a mainstay of clinical imaging, and PET is now one of the world's fastest growing medical imaging techniques, owing to its dramatic contributions to cancer imaging and other applications. Emission Tomography: The Fundamentals of PET and SPECT is an essential resource for understanding the technology of SPECT and PET, the most widely used forms of molecular imaging.*Contains thorough tutorial treatments, coupled with coverage of advanced topics*Three of the four holders of the prestigious Institute of Electrical and Electronics Engineers Medical Imaging Scientist Award are chapter contributors*Include color artwork




Neurology in Clinical Practice


Book Description

New edition, completely rewritten, with new chapters on endovascular surgery and mitochrondrial and ion channel disorders.




Brain Imaging in Epilepsy


Book Description

Recent advances in functional neuroimaging have greatly enhanced our understanding of brain functionality through the ability to visualize brain processes at work. Brain Imaging in Epilepsy provides an overview of the techniques that have been developed, including positron emission tomography (PET), single photon emission computed tomography (SPECT), functional magnetic resonance imaging (fMRI), diffusion weighted imaging (DWI) and magnetic resonance spectroscopy (MRS). Relevant features of the basic neuroscience of epilepsy are reviewed, and the application of these techniques in diagnosing, treating and developing new treatments for epilepsy is discussed. This book will prove fascinating to a large audience from practicing neurologists and radiologists, to junior doctors and students of medicine, neuroscience and medical physics.