Spectral, Photon Counting Computed Tomography


Book Description

Spectral, Photon Counting Computed Tomography is a comprehensive cover of the latest developments in the most prevalent imaging modality (x-ray computed tomography (CT)) in its latest incarnation: Spectral, Dual-Energy, and Photon Counting CT. Disadvantages of the conventional single-energy technique used by CT technology are that different materials cannot be distinguished and that the noise is larger. To address these problems, a novel spectral CT concept has been proposed. Spectral Dual-Energy CT (DE-CT) acquires two sets of spectral data, and Spectral Photon Counting CT (PC-CT) detects energy of x-ray photons to reveal additional material information of objects by using novel energy-sensitive, photon-counting detectors. The K-edge imaging may be a gateway for functional or molecular CT. The book covers detectors and electronics, image reconstruction methods, image quality assessments, a simulation tool, nanoparticle contrast agents, and clinical applications for spectral CT.







Radiation Detection Systems


Book Description

The advances in semiconductor detectors, scintillators, photodetectors such as silicon photomultipliers (SiPM), and reaodut electronics have experienced tremendous growth in recent years in terms of basic technologies and variety of applications.The second edition of the book Radiation Detection Systems presents variety of radiation detection systems giving readers a broad view of the state-of–the-art in the design of detectors, front-end electronics and systems offering optimized choices of the detection tools for a particular application. The new edition has been divided into two volumes. This first volume, on Sensor Materials, Systems, Technology and Characterization Measurements puts emphasis on sensor materials, detector structures, front electronics technology and their designs as well as system optimization for different applications. Also, the book include characterization measurements of the developed detection systems. Featuring contributions from leading experts and pioneers in their respective fields, this book • describes progress in growth technologies of cadmium zinc telluride (CdZnTe) and cadmium telluride (CdTe) materials • shows variety of specific detector structure designs and their integration with front-end amplification/processing electronics • presents detection systems based on CdZnTe and CdTe detector technologies that are optimized for specific applications. The designed systems are characterized in terms of their spectral responses, spatial and timing resolutions • addresses incomplete charge collection, pulse pileup, charge sharing between neighboring detector pixels and other phenomena that can degrade the spectral response of photon-counting detectors • reports new developments of silicon photomultipliers used for reading the light from scintillators that starting to make a big impact particularly in the design concepts of novel medical instrumentation With its combined coverage of new materials and innovative new system approaches, as well as a succinct overview of recent developments, this book is an invaluable tool for any engineer, professional, or student working in electronics or an associated field. Readers can refer to the second book to get a detailed understanding of more specific applications of the detection systems in medical imaging, industrial testing and security applications.




Radiation Detectors for Medical Imaging


Book Description

Radiation Detectors for Medical Imaging discusses the current state of the art and future prospects of photon-counting detectors for medical imaging applications. Featuring contributions from leading experts and pioneers in their respective fields, this book:Describes x-ray spectral imaging detectors based on cadmium zinc telluride (CdZnTe) and cad




Photon Counting Computed Tomography


Book Description

This book will provide readers with a good overview of some of most recent advances in the field of Photon Counting CT technology for X-ray medical imaging, especially as it pertains to new detectors. There will be a good mixture of general chapters in both technology and applications in CT medical imaging. The book will have an in-depth review of the research topics from world-leading specialists in the field. The conversion of the X-ray signal into analogue/digital value will be covered in some chapters. The authors also provide a review of CMOS chips for X-ray image sensors, methods of material discrimination and image reconstruction techniques. Covers a broad range of topics, including an introduction to novel spectral Computed Tomography; Includes in-depth analysis on how to optimize X-ray detection; Discusses analysis of electronics for X-ray detection.







Radiation Detection Systems


Book Description

The advances in semiconductor detectors, scintillators, photodetectors such as silicon photomultipliers (SiPM), and readout electronics have experienced tremendous growth in recent years in terms of basic technologies and a variety of applications. The second edition of Radiation Detection Systems presents variety of radiation detection systems, giving readers a broad view of the state-of-the-art in the design of detectors, front-end electronics, and systems offering optimized choices of the detection tools for a particular application. The new edition has been divided into two volumes. This volume on Medical Imaging, Industrial Testing, and Security Applications presents specific applications of the detection systems in medical imaging, industrial testing, and security applications. These newely developed technologies play a vital role in the detection, diagnosis, and treatment of major human diseases. Featuring contributions from leading experts and pioneers in their respective fields, this book: Describes new advances in development of detection systems based on CdZnTe (CZT) and CdTe detectors utilizing a direct conversion of radiation to electric signals Reports a recent progress in technologies and performance of SiPM used for reading the light from scintillators Explores exciting new application opportunities created by development of the cutting-edge detection technologies in X-ray spectroscopy, computed tomography (CT), bone dosimetry, and nuclear medicine (PET, SPECT) Considers the future use of photon-counting detectors in clinical CT scanners providing K-edge imaging to reduce the amount of contrast agents and ultimately offering both an anatomical and a functional information Describes, uses of radiation detection systems in security applications such as luggage scanning, dirty bomb detection, and border control With its combined coverage of new materials and innovative new system approaches, as well as a succinct overview of recent developments, this book is an invaluable tool for any engineer, professional, or student working in electronics or an associated field. Readers can refer to the other volume, Sensor Materials, Systems, Technology, and Characterization Measurements, which puts emphasis on sensor materials, detector structures, front electronics technology, and their designs and system optimization for different applications.




Spectral Multi-Detector Computed Tomography (sMDCT)


Book Description

X-ray computed tomography (CT) has been one of the most popular diagnostic imaging modalities for decades in the clinic for saving patients’ lives or improving their quality of life. This book is an introductory one-stop shop for technological and clinical topics in multi-detector computed tomography (MDCT). Starting with MDCT’s fundamentals in physics and mathematics, the book provides an in-depth introduction to its system architecture and imaging chain, signal detection via energy-integration and photon-counting mechanisms, clinical application-driven scan modes and protocols, analytic and iterative image reconstruction solutions, and spectral imaging – the latest technological advancement in MDCT. The book extends its coverage on image quality assessment under the theory of signal detection and statistical decision. In recognition of its clinical relevance for conspicuity enhancement in angiographic and parenchymal imaging applications, the book features a chapter dedicated to the fundamental (chemical, physical and physicochemical) properties and clinical administration of iodinated contrast agent. The book ends with an outlook of the contrast agents that are novel in material and delivery, and their synergy with spectral MDCT to elevate CT’s contrast resolution in cardiovascular, neurovascular and oncologic applications. This book will be an invaluable reference for researchers, engineers, radiological physicians and technologists, and graduate and senior undergraduate students. Features Provides an accessible introduction to the subject Up to date with the latest advances in emerging technologies and procedures Provides a historical overview of CT technology Xiangyang Tang, PhD, is an imaging scientist with extensive research and development experience in industry (GE Healthcare), academia (Emory University School of Medicine) and the clinic (Emory Healthcare). With a focus on computed tomography, Tang has been working in the field of medical imaging for more than 20 years. He is a professor of radiology and imaging sciences at Emory University School of Medicine, Fellow of SPIE (International Society for Optics and Photonics) and Fellow of AAPM (American Association of Physicists in Medicine). Along with the publication of more than 200 papers in leading scientific journals and conferences, his contributions to the scientific community include serving as associate editor for a number of prestigious journals, in addition to working on the scientific committees of leading conferences and panels for numerous federal and foundational study sections.