Spliced


Book Description

Sixteen-year-old Jimi knows people change, but nothing could prepare her for what’s about to happen to her best friend, Del. Over the years, their friendship has been evolving—and Jimi is starting to wonder if they could become more than friends. But Del is obsessed with becoming a chimera: a person with animal features, achieved by splicing animal genes into their own DNA. It's a dangerous and controversial process, provided illegally by back-alley doctors called genies. The dramatic physical changes chimeras go through have scared lawmakers into drafting legislation to declare chimeras officially non-human— taking away all protections under the law. When Del goes missing, Jimi is desperate to find him before he alters himself forever. To save him, Jimi must risk her life—all while knowing that if getting spliced is the choice Del has made, it means he’s leaving her behind forever. Unlikely allies and powerful enemies clash as Jimi questions her beliefs and uncovers closely-guarded secrets about her own past. Set in a near-future society where technology is redefining what it means to be human, Spliced is part science fiction, part political thriller, raising questions about genetic modification and how we treat each other that will stay with you long after the final page. The hardcover and paperback editions features a striking, texturally-embossed spot gloss cover, and the paperback features a sneak-peak at the heart-pounding sequel, Splintered. A Hal Clement Notable Young Adult Book 2018




Splicing Modern Ropes


Book Description

The time when every vessel going to sea made use of 3-strand rope has gone. Splicing that type of rope and cord is relatively straightforward. Nowadays the most common type of rope used on board yachts, dinghies, motorboats, working boats and ferries is braided rope. Few people have the knowledge to splice it, or even where to start. Splicing Modern Ropes is the first guide to this essential skill. It explains why splices are better – and stronger – than knots or shackles for joining or shortening rope, and how to go about it. With this skill, yachtsmen can customise their ropes, optimise their deck layout, taper their sheets for ease of handling, and splice an extra cover on their ropes to give better grip, avoid chafe and make them last longer. Using clear, step-by-step photography and detailed instructions, this book will guide readers through all the stages required to make strong, reliable splices.




Splice Magic


Book Description

Splice Magic is a groundbreaking quilting technique by Tiffany Hayes of Needle in a Hayes Stack. Tiffany Hayes, together with Kristie J. Smith and a host of friends, created a pattern book of 10 quilts to showcase the Splice Magic technique. The book is sponsored by Stitchin' Heaven, in Quitman, TX.




Building Code Requirements for Structural Concrete (ACI 318-08) and Commentary


Book Description

The quality and testing of materials used in construction are covered by reference to the appropriate ASTM standard specifications. Welding of reinforcement is covered by reference to the appropriate AWS standard. Uses of the Code include adoption by reference in general building codes, and earlier editions have been widely used in this manner. The Code is written in a format that allows such reference without change to its language. Therefore, background details or suggestions for carrying out the requirements or intent of the Code portion cannot be included. The Commentary is provided for this purpose. Some of the considerations of the committee in developing the Code portion are discussed within the Commentary, with emphasis given to the explanation of new or revised provisions. Much of the research data referenced in preparing the Code is cited for the user desiring to study individual questions in greater detail. Other documents that provide suggestions for carrying out the requirements of the Code are also cited.




Splicing Mine Cables


Book Description




Molecular Cell Biology


Book Description

The fifth edition provides an authoritative and comprehensive vision of molecular biology today. It presents developments in cell birth, lineage and death, expanded coverage of signaling systems and of metabolism and movement of lipids.




Optical Fiber Fusion Splicing


Book Description

This book is an up-to-date treatment of optical fiber fusion splicing incorporating all the recent innovations in the field. It provides a toolbox of general strategies and specific techniques that the reader can apply when optimizing fusion splices between novel fibers. It specifically addresses considerations important for fusion splicing of contemporary specialty fibers including dispersion compensating fiber, erbium-doped gain fiber, polarization maintaining fiber, and microstructured fiber. Finally, it discusses the future of optical fiber fusion splicing including silica and non-silica based optical fibers as well as the trend toward increasing automation. Whilst serving as a self-contained reference work, abundant citations from the technical literature will enable readers to readily locate primary sources.




RNA: Catalysis, Splicing, Evolution


Book Description

The conference on "RNA: Catalysis, Splicing, Evolution" brought together a unique assembly of scientific leaders in this currently very important field. Two participants of this Conference, Drs. T.R. Cech and S. Altman, were just awarded the 1989 Nobel prize in chemistry, which attests to the timeliness of this volume. The critical reviews authored by these two prominent scientists are included. For those scientists with roots in this field, who do not subscribe to GENE, this is an excellent opportunity to obtain a masterly collection of papers. All the original papers and reviews have undergone the rigorous peer review of the journal "Gene".




Splicing of Optical Fibers


Book Description




Regulation of Alternative Splicing


Book Description

The discovery in 1977 that genes are split into exons and introns has done away with the one gene - one protein dogma. Indeed, the removal of introns from the primary RNA transcript is not necessarily straightforward since there may be optional pathways leading to different messenger RNAs and consequently to different proteins. Examples of such an alternative splicing mechanism cover all fields of biology. Moreover, there are plenty of occurrences where deviant splicing can have pathological effects. Despite the high number of specific cases of alternative splicing, it was not until recently that the generality and extent of this phenomenon was fully appreciated. A superficial reading of the preliminary sequence of the human genome published in 2001 led to the surprising, and even deceiving to many scientists, low number of genes (around 32,000) which contrasted with the much higher figure around 150,000 which was previously envisioned. Attempts to make a global assessment of the use of alternative splicing are recent and rely essentially on the comparison of genomic mRNA and EST sequences as reviewed by Thanaraj and Stamm in the first chapter of this volume. Most recent estimates suggest that 40-60% of human genes might be alternatively spliced, as opposed to about 22% for C. elegans.