State of the Art Brain Tumor Diagnostics, Imaging, and Therapeutics, an Issue of Neuroimaging Clinics


Book Description

This Neuroimaging publication presents information in three distinct sections: Diagnostics, Planning/Imaging, and Therapeutics. Topics include State of the Art Pathology (New tools, New WHO classification/implications); Applications of nanotechnology in the imaging and therapy of brain tumors; Molecular Tools (Biology, Prognosis and Therapeutic Triage in Gliomas); Surgical planning and intra-operative MR in brain tumor surgery; Imaging of brain tumors via DTI and fMRI; Imaging of brain tumors via MR Spectroscopy and Metabolic Imaging; Imaging of brain tumors: Perfusion Permeability; Novel Gadolinium liposomal contrast agents; Current status and future potential of MRI-guided focused ultrasound surgery; Update on surgically based clinical trials in brain tumors including new neurosurgical techniques; Novel medical therapeutics in brain tumors, including targeted molecular therapies, current and future clinical trials; and Radiation oncology in brain tumors, current approaches and clinical trials in progress.







Brain Tumor Imaging


Book Description

This book describes the basics, the challenges and the limitations of state of the art brain tumor imaging and examines in detail its impact on diagnosis and treatment monitoring. It opens with an introduction to the clinically relevant physical principles of brain imaging. Since MR methodology plays a crucial role in brain imaging, the fundamental aspects of MR spectroscopy, MR perfusion and diffusion-weighted MR methods are described, focusing on the specific demands of brain tumor imaging. The potential and the limits of new imaging methodology are carefully addressed and compared to conventional MR imaging. In the main part of the book, the most important imaging criteria for the differential diagnosis of solid and necrotic brain tumors are delineated and illustrated in examples. A closing section is devoted to the use of MR methods for the monitoring of brain tumor therapy. The book is intended for radiologists, neurologists, neurosurgeons, oncologists and other scientists in the biomedical field with an interest in neuro-oncology.




Functional Brain Tumor Imaging


Book Description

This book presents a comprehensive overview of current state-of-the-art clinical physiological imaging of brain tumors. It focuses on the clinical applications of various modalities as they relate to brain tumor imaging, including techniques such as blood oxygen level dependent functional magnetic resonance imaging, diffusion tensor imaging, magnetic source imaging/magnetoencephalography, magnetic resonance perfusion imaging, magnetic resonance spectroscopic imaging, amide proton transfer imaging, high angular resolution diffusion imaging, and molecular imaging. Featuring contributions from renowned experts in functional imaging, this book examines the diagnosis and characterization of brain tumors, details the application of functional imaging to treatment planning and monitoring of therapeutic intervention, and explores future directions in physiologic brain tumor imaging. Intended for neuro-oncologists, neurosurgeons, neuroradiologists, residents, and medical students, Functional Imaging of Brain Tumors is a unique resource that serves to advance patient care and research in this rapidly developing field.




Advances in Surgical Pathology: Brain Cancer


Book Description

Apply a state-of-the-art, integrated approach to brain cancer diagnosis and staging withAdvances in Surgical Pathology: Brain Cancer. Distinguished experts provide you with concise, current, and well-rounded guidance on all 130 brain tumor entities listed in the most recent WHO classification, with an emphasis on practical issues and new developments. This cutting-edge surgical pathology reference is an ideal tool to help you update your knowledge and skills and solve difficult diagnostic dilemmas, as well as a valuable resource for certification and recertification preparation.




Imaging of Brain Tumors with Histological Correlations


Book Description

This volume provides a thorough treatment of the diagnosis of brain tumors by correlating radiographic image features to the underlying pathology. Theoretical considerations and illustrations depicting common and uncommon imaging characteristics of various brain tumors are presented. All modern imaging modalities are used to complete a diagnostic overview of brain tumors with emphasis on recent advances in diagnostic neuroradiology. The book has been designed as a clinical tool for radiologists and other clinicians interested in the current diagnostic approach to brain tumors.




Glioblastoma


Book Description

Neuroimaging plays a central role in the initial diagnosis and subsequent monitoring of multimodal therapies offered to patients with glioblastoma the most malignant type of brain cancer. The authors present a comprehensive description of current state-of-the-art clinical neuroimaging for glioblastoma. They cover the basic concepts and most recent applications of clinical structural neuroimaging, as well as the latest innovations and up-and-coming techniques for functional imaging of glioblastoma patients.Few comprehensive books are available in this challenging field of clinical medicine. The co-editors are experienced academic neuroradiologists with an active interest in clinical imaging and research of glioblastoma, all within a vibrant clinical environment at Stanford University where the latest innovations in glioblastoma imaging and treatment are being developed. In compiling this book, the co-editors have called upon many of the worlds best clinical and basic neuroscientists specializing in the management of patients with this malignancy, for their expert input on the latest imaging developments and applicable research into glioblastoma.This book is intended for neuroradiologists, neuro-oncologists, neurosurgeons, radiation therapists, and other physicians and scientists engaged in the study and clinical management of patients with glioblastoma. It should also serve as a unique educational and research resource for students and more experienced practitioners alike within this rapidly evolving field.




Methods of Cancer Diagnosis, Therapy, and Prognosis


Book Description

This eighth volume in the series Methods of Cancer Diagnosis, Therapy, and Prognosis discusses in detail the classification of the CNS tumors as well as brain tumor imaging. Scientists and Clinicians have contributed state of the art chapters on their respective areas of expertise, providing the reader a whole field view of the CNS tumors and brain tumor imaging in Europe. This fully illustrated volume: Explains the genetics of malignant brain tumors and gene amplification using quantitative-PCR; Presents a large number of standard and new imaging modalities, including magnetic resonance imaging, functional magnetic resonance imaging, diffusion tensor imaging, amide proton transfer imaging, positron emission tomography, single photon emission computed tomography, magnetic resonance single voxel spectroscopy and intraoperative ultrasound imaging, for staging and diagnosing various primary and secondary brain cancers; Explains the usefulness of imaging methods for planning and monitoring (assessment) therapy for cancers; Discusses diagnosis and treatment of primary CNS lymphomas, CNS atypical teratoid/rhabdoid and CNS Rosai-Dorfman disease; Includes the subject of translational medicine. Professor Hayat has summarized the problems associated with the complexities of research publications and has been successful in editing a must-read volume for oncologists, cancer researchers, medical teachers and students of cancer biology.




Malignant Brain Tumors


Book Description

This text addresses all aspects of patient evaluation and care. This includes new findings in imaging that provide a better understanding of the extent of the lesion as well as its relationship with critical neuroanatomic function. The evolution of intraoperative imaging, functional brain mapping,and technology to identify tumor from brain is covered. This has significantly improved the ability of surgeons to more safely and aggressively remove tumors.More importantly, a better understanding of tumor biology and genomics has created an opportunity to significantly revise tumor classification and better select optimal therapy for individual patients. The text covers novel and innovative treatment options including immunotherapy, tumor vaccines, antiangiogenic agents,and personalized cancer treatment. In addition, novel agent delivery techniques are covered to offer the potential for increasing the effectiveness of treatment by delivering active agents directly where they are needed most. Malignant Brain Tumors: State-of-the-Art Treatment provides a comprehensive overview of treatment for malignant gliomas, and will prove useful by updating physicians on new therapeutic paradigms and what is on the horizon for the near future. This text will be informative for surgeons, oncologists, neurologists, residents and students who treat these patients,as well as those who are training for a career in managing patients with these challenging tumors.




Diseases of the Brain, Head & Neck, Spine


Book Description

Written by internationally renowned experts, this volume is a collection of chapters dealing with imaging diagnosis and interventional therapies in neuroradiology and diseases of the spine. The different topics are disease-oriented and encompass all the relevant imaging modalities including X-ray technology, nuclear medicine, ultrasound and magnetic resonance, as well as image-guided interventional techniques. It represents a unique experience for residents in radiology as well as for experienced radiologists wishing to be updated on the current state of the art.