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An Introduction to Statistical Genetic Data Analysis

Author : Melinda C. Mills

Publisher : MIT Press

Page : 433 pages

File Size : 17,17 MB

Release : 2020-02-18

Category : Science

ISBN : 0262538385

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Book Description

A comprehensive introduction to modern applied statistical genetic data analysis, accessible to those without a background in molecular biology or genetics. Human genetic research is now relevant beyond biology, epidemiology, and the medical sciences, with applications in such fields as psychology, psychiatry, statistics, demography, sociology, and economics. With advances in computing power, the availability of data, and new techniques, it is now possible to integrate large-scale molecular genetic information into research across a broad range of topics. This book offers the first comprehensive introduction to modern applied statistical genetic data analysis that covers theory, data preparation, and analysis of molecular genetic data, with hands-on computer exercises. It is accessible to students and researchers in any empirically oriented medical, biological, or social science discipline; a background in molecular biology or genetics is not required. The book first provides foundations for statistical genetic data analysis, including a survey of fundamental concepts, primers on statistics and human evolution, and an introduction to polygenic scores. It then covers the practicalities of working with genetic data, discussing such topics as analytical challenges and data management. Finally, the book presents applications and advanced topics, including polygenic score and gene-environment interaction applications, Mendelian Randomization and instrumental variables, and ethical issues. The software and data used in the book are freely available and can be found on the book's website.



Statistical Analysis and Data Display

Author : Richard M. Heiberger

Publisher : Springer Science & Business Media

Page : 739 pages

File Size : 19,33 MB

Release : 2013-06-29

Category : Mathematics

ISBN : 1475742843

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Book Description

This presentation of statistical methods features extensive use of graphical displays for exploring data and for displaying the analysis. The authors demonstrate how to analyze data—showing code, graphics, and accompanying computer listings. They emphasize how to construct and interpret graphs, discuss principles of graphical design, and show how tabular results are used to confirm the visual impressions derived from the graphs. Many of the graphical formats are novel and appear here for the first time in print.



Statistical Methods for the Information Professional

Author : Liwen Vaughan

Publisher : Information Today, Inc.

Page : 248 pages

File Size : 19,71 MB

Release : 2001

Category : Business & Economics

ISBN : 9781573871105

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Book Description

For most of us, "painless" is not the word that comes to mind when we think of statistics, but author and educator Liwen Vaughan wants to change that. In this unique and useful book, Vaughan clearly explains the statistical methods used in information science research, focusing on basic logic rather than mathematical intricacies. Her emphasis is on the meaning of statistics, when and how to apply them, and how to interpret the results of statistical analysis. Through the use of real-world examples, she shows how statistics can be used to improve services, make better decisions, and conduct more effective research. Whether you are doing statistical analysis or simply need to better understand the statistics you encounter in professional literature and the media, this book will be a valuable addition to your personal toolkit. Includes more than 80 helpful figures and tables, 7 appendices, bibliography, index.



Statistical Adjustment of Data

Author : William Edwards Deming

Publisher :

Page : 284 pages

File Size : 45,17 MB

Release : 1946

Category : Correlation (Statistics)

ISBN :

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Statistical Data Analysis

Author : Glen Cowan

Publisher : Oxford University Press

Page : 218 pages

File Size : 43,4 MB

Release : 1998

Category : Mathematics

ISBN : 0198501560

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Book Description

This book is a guide to the practical application of statistics in data analysis as typically encountered in the physical sciences. It is primarily addressed at students and professionals who need to draw quantitative conclusions from experimental data. Although most of the examples are takenfrom particle physics, the material is presented in a sufficiently general way as to be useful to people from most branches of the physical sciences. The first part of the book describes the basic tools of data analysis: concepts of probability and random variables, Monte Carlo techniques,statistical tests, and methods of parameter estimation. The last three chapters are somewhat more specialized than those preceding, covering interval estimation, characteristic functions, and the problem of correcting distributions for the effects of measurement errors (unfolding).



Information Criteria and Statistical Modeling

Author : Sadanori Konishi

Publisher : Springer Science & Business Media

Page : 282 pages

File Size : 37,48 MB

Release : 2008

Category : Business & Economics

ISBN : 0387718869

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Book Description

Statistical modeling is a critical tool in scientific research. This book provides comprehensive explanations of the concepts and philosophy of statistical modeling, together with a wide range of practical and numerical examples. The authors expect this work to be of great value not just to statisticians but also to researchers and practitioners in various fields of research such as information science, computer science, engineering, bioinformatics, economics, marketing and environmental science. It’s a crucial area of study, as statistical models are used to understand phenomena with uncertainty and to determine the structure of complex systems. They’re also used to control such systems, as well as to make reliable predictions in various natural and social science fields.





Statistical Methods in Water Resources

Author : D.R. Helsel

Publisher : Elsevier

Page : 539 pages

File Size : 30,23 MB

Release : 1993-03-03

Category : Science

ISBN : 0080875084

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Book Description

Data on water quality and other environmental issues are being collected at an ever-increasing rate. In the past, however, the techniques used by scientists to interpret this data have not progressed as quickly. This is a book of modern statistical methods for analysis of practical problems in water quality and water resources.The last fifteen years have seen major advances in the fields of exploratory data analysis (EDA) and robust statistical methods. The 'real-life' characteristics of environmental data tend to drive analysis towards the use of these methods. These advances are presented in a practical and relevant format. Alternate methods are compared, highlighting the strengths and weaknesses of each as applied to environmental data. Techniques for trend analysis and dealing with water below the detection limit are topics covered, which are of great interest to consultants in water-quality and hydrology, scientists in state, provincial and federal water resources, and geological survey agencies.The practising water resources scientist will find the worked examples using actual field data from case studies of environmental problems, of real value. Exercises at the end of each chapter enable the mechanics of the methodological process to be fully understood, with data sets included on diskette for easy use. The result is a book that is both up-to-date and immediately relevant to ongoing work in the environmental and water sciences.



Practical Statistics for Data Scientists

Author : Peter Bruce

Publisher : "O'Reilly Media, Inc."

Page : 322 pages

File Size : 31,20 MB

Release : 2017-05-10

Category : Computers

ISBN : 1491952911

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Book Description

Statistical methods are a key part of of data science, yet very few data scientists have any formal statistics training. Courses and books on basic statistics rarely cover the topic from a data science perspective. This practical guide explains how to apply various statistical methods to data science, tells you how to avoid their misuse, and gives you advice on what's important and what's not. Many data science resources incorporate statistical methods but lack a deeper statistical perspective. If you’re familiar with the R programming language, and have some exposure to statistics, this quick reference bridges the gap in an accessible, readable format. With this book, you’ll learn: Why exploratory data analysis is a key preliminary step in data science How random sampling can reduce bias and yield a higher quality dataset, even with big data How the principles of experimental design yield definitive answers to questions How to use regression to estimate outcomes and detect anomalies Key classification techniques for predicting which categories a record belongs to Statistical machine learning methods that “learn” from data Unsupervised learning methods for extracting meaning from unlabeled data



Statistical Analysis of Spherical Data

Author : N. I. Fisher

Publisher : Cambridge University Press

Page : 358 pages

File Size : 11,81 MB

Release : 1993-08-19

Category : Mathematics

ISBN : 9780521456999

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Book Description

This is the first comprehensive, yet clearly presented, account of statistical methods for analysing spherical data. The analysis of data, in the form of directions in space or of positions of points on a spherical surface, is required in many contexts in the earth sciences, astrophysics and other fields, yet the methodology required is disseminated throughout the literature. Statistical Analysis of Spherical Data aims to present a unified and up-to-date account of these methods for practical use. The emphasis is on applications rather than theory, with the statistical methods being illustrated throughout the book by data examples.