Fundamentals and Applications of Fourier Transform Mass Spectrometry


Book Description

Fundamentals and Applications of Fourier Transform Mass Spectrometry is the first book to delve into the underlying principles on the topic and their linkage to industrial applications. Drs. Schmitt-Kopplin and Kanawati have brought together a team of leading experts in their respective fields to present this technique from many different perspectives, describing, at length, the pros and cons of FT-ICR and Orbitrap. Numerous examples help researchers decide which instruments to use for their particular scientific problem and which data analysis methods should be applied to get the most out of their data. - Covers FT-ICR-MS and Orbitrap's fundamentals, enhancing researcher knowledge - Includes details on ion sources, data processing, chemical analysis and imaging - Provides examples across the wide spectrum of applications, including omics, environmental, chemical, pharmaceutical and food analysis




Gas Phase Ion Chemistry


Book Description

Gas Phase Ion Chemistry, Volume 2 covers the advances in gas phase ion chemistry. The book discusses the stabilities of positive ions from equilibrium gas-phase basicity measurements; the experimental methods used to determine molecular electron affinities, specifically photoelectron spectroscopy, photodetachment spectroscopy, charge transfer, and collisional ionization; and the gas-phase acidity scale. The text also describes the basis of the technique of chemical ionization mass spectrometry; the energetics and mechanisms of unimolecular reactions of positive ions; and the photodissociation of gas-phase ions. The applications of molecular beam techniques to the study of ion-molecule collisions; as well as the variational treatment of charge transfer reactions are also encompassed. Chemists and biochemists will find the book invaluable.







Ion-molecule


Book Description




Techniques for the Study of Ion-Molecule Reactions


Book Description

The first comprehensive collection of all the major techniques used to study gas phase interactions is presented in this volume. With complete coverage of what a given technique can accomplish, its advantages and disadvantages, the book is designed to teach advanced students and researchers entering the field how to investigate a broad range of topics. Included is coverage of traditional topics such as ion cyclotron resonance, as well as more recent innovations, including Fourier transform mass spectrometry and ionic cluster studies. Several diagrams of instrumentation and examples of experimental data are also provided.




Medical Applications of Mass Spectrometry


Book Description

Mass spectrometry is fast becoming an indispensable field for medical professionals. The mass spectrometric analysis of metabolites and proteins promises to revolutionize medical research and clinical diagnostics. As this technology rapidly enters the medical field, practicing professionals and students need to prepare to take full advantage of its capabilities. Medical Applications of Mass Spectrometry addresses the key issues in the medical applications of mass spectrometry at the level appropriate for the intended readership. It will go a long way to help the utilization of mass spectrometry in medicine.The book comprises five parts. A general overview is followed by a description of the basic sampling and separation methods in analytical chemistry. In the second part a solid foundation in mass spectrometry and modern techniques of data analysis is presented. The third part explains how mass spectrometry is used in exploring various classes of biomolecules, including proteins and lipids. In the fourth section mass spectrometry is introduced as a diagnostic tool in clinical treatment, infectious pathogen research, neonatal diagnostics, cancer, brain and allergy research, as well as in various fields of medicine: cardiology, pulmonology, neurology, psychiatric diseases, hemato-oncology, urologic diseases, gastrointestinal diseases, gynecology and pediatrics. The fifth part covers emerging applications in biomarker discovery and in mass spectrometric imaging.* Provides a broad look at how the medical field is benefiting from advances in mass spectrometry.* Guides the reader from basic principles and methods to cutting edge applications.* There is NO comparable book on the market to fill this fast growing field.




Fundamentals of Gas Phase Ion Chemistry


Book Description

This volume presents the proceedings of the 1990 Advanced Study Institute entitled "Fundamentals of Gas Phase Ion Chemistry" held at Mont Ste. Odile , Alsace, France, 25th June -6th July, 1990. The Institute brought together over 100 physicists, physical and organic chemists working on a wide variety of topics with gas-phase ion chemistry as the common theme. Many different viewpoints, making use of very different experimental and theoretical approaches, were brought to bear on the subject and provided a stimulating and up-to-date account of the subject. Although the Institute was built around the invited lectures, many specific points were addressed in workshops which consisted of informal discussion groups which were organised by participants during the Institute. This volume therefore contains not only chapters based on the lectures but summaries of many of the workshops which adds considerably to the diversity of information presented. This Advanced Study Institute was the fifth in a series of NATO-sponsored institutes devoted to various aspects of the physics and chemistry of gas phase ions. These meetings have been held every four years since the first, held in Biarritz in 1974, considered "Interactions between Ions and Molecules". The five volumes which comprise the proceedings of these meetings illustrate very clearly the many advances in theory and experiment which have taken place over the last 20 years.