SYNTHETIC MICROBIAL RESEARCH - CHALLENGES AND PROSPECTS


Book Description

Synthetic microbial research-challenges and prospects are more inclined towards interdisciplinary studies. Recent developments in the Microbial technologies have led to a better understanding of living systems and this has removed the demarcations between various disciplines of biological sciences. A new trend in bioscience incorporates Bitechnology and biological research involving Agrobacterium mediated gene transfer in medicinal plants for enhanced production of secondary metabolites, Biohydrogen and bioplastic from photosynthetic bacteria – A State of art review, Microbial Cellulase- An Overview, Microbial Nanotechnology: Challenges and Prospects for Green Biocatalytic Synthesis of Nanoscale Materials for Sensory and Biomedical Applications, Probiotics and Its application, Impact of Copper on water treatment plant, Chitin and Chitinases: An overview of production and applications, Therapeutic approaches for the manageent of Polycystic Ovarian Syndrome, The 3Rs of managing solid waste: reduce, reuse and recycle, Green Synthesis of Algal Nanoparticles and its Biotechnological Potentials, Biopigments, Microbial profiling of vermicompost.




The Chemistry of Microbiomes


Book Description

The 21st century has witnessed a complete revolution in the understanding and description of bacteria in eco- systems and microbial assemblages, and how they are regulated by complex interactions among microbes, hosts, and environments. The human organism is no longer considered a monolithic assembly of tissues, but is instead a true ecosystem composed of human cells, bacteria, fungi, algae, and viruses. As such, humans are not unlike other complex ecosystems containing microbial assemblages observed in the marine and earth environments. They all share a basic functional principle: Chemical communication is the universal language that allows such groups to properly function together. These chemical networks regulate interactions like metabolic exchange, antibiosis and symbiosis, and communication. The National Academies of Sciences, Engineering, and Medicine's Chemical Sciences Roundtable organized a series of four seminars in the autumn of 2016 to explore the current advances, opportunities, and challenges toward unveiling this "chemical dark matter" and its role in the regulation and function of different ecosystems. The first three focused on specific ecosystemsâ€"earth, marine, and humanâ€"and the last on all microbiome systems. This publication summarizes the presentations and discussions from the seminars.




Biodefense in the Age of Synthetic Biology


Book Description

Scientific advances over the past several decades have accelerated the ability to engineer existing organisms and to potentially create novel ones not found in nature. Synthetic biology, which collectively refers to concepts, approaches, and tools that enable the modification or creation of biological organisms, is being pursued overwhelmingly for beneficial purposes ranging from reducing the burden of disease to improving agricultural yields to remediating pollution. Although the contributions synthetic biology can make in these and other areas hold great promise, it is also possible to imagine malicious uses that could threaten U.S. citizens and military personnel. Making informed decisions about how to address such concerns requires a realistic assessment of the capabilities that could be misused. Biodefense in the Age of Synthetic Biology explores and envisions potential misuses of synthetic biology. This report develops a framework to guide an assessment of the security concerns related to advances in synthetic biology, assesses the levels of concern warranted for such advances, and identifies options that could help mitigate those concerns.







Encyclopedia of Renewable Energy, Sustainability and the Environment


Book Description

Encyclopedia of Renewable Energy, Sustainability and the Environment, Four Volume Set comprehensively covers all renewable energy resources, including wind, solar, hydro, biomass, geothermal energy, and nuclear power, to name a few. In addition to covering the breadth of renewable energy resources at a fundamental level, this encyclopedia delves into the utilization and ideal applications of each resource and assesses them from environmental, economic, and policy standpoints. This book will serve as an ideal introduction to any renewable energy source for students, while also allowing them to learn about a topic in more depth and explore related topics, all in a single resource.Instructors, researchers, and industry professionals will also benefit from this comprehensive reference. - Covers all renewable energy technologies in one comprehensive resource - Details renewable energies' processes, from production to utilization in a single encyclopedia - Organizes topics into concise, consistently formatted chapters, perfect for readers who are new to the field - Assesses economic challenges faced to implement each type of renewable energy - Addresses the challenges of replacing fossil fuels with renewables and covers the environmental impacts of each renewable energy




Treating Infectious Diseases in a Microbial World


Book Description

Humans coexist with millions of harmless microorganisms, but emerging diseases, resistance to antibiotics, and the threat of bioterrorism are forcing scientists to look for new ways to confront the microbes that do pose a danger. This report identifies innovative approaches to the development of antimicrobial drugs and vaccines based on a greater understanding of how the human immune system interacts with both good and bad microbes. The report concludes that the development of a single superdrug to fight all infectious agents is unrealistic.




Microbial Vitamins and Carotenoids in Food Biotechnology


Book Description

In recent years, there has been a global surge in the production and application of vitamins and pigments in food and pharmaceuticals industries, leading to draw the attention of scientific communities to develop novel strategies to cope with world demand. Microbial vitamins and carotenoids in food biotechnology: Novel source and potential applications allow the audience to understand the current status of the biotechnological approaches used for the production of vitamins and carotenoids from microorganisms. The title provides important insights to understand the molecular mechanisms involved in microbial biosynthesis of vitamins and carotenoids. The chapters, all written by leading researchers from academia, help to put forward all the latest advancement concerning the production and applications of microbial vitamins and carotenoids. The book also provides the sustainable alternative to chemically synthesized compound and presents the wide coverage for the most promising sources of vitamins and carotenoids in food and pharmaceutical industries. This is a complete and unique resource beneficial for the scientific communities as well as food science and nutrition research students. - Thoroughly explores biotechnological approaches surrounding the production and application of microbial vitamins and carotenoids in food processing and manufacturing industries - Covers the major portion of novel source and various biotechnological approaches used for the production of various types of vitamins and carotenoids from microorganisms and their applications in food industry - Contains up-to-date information required for the formulations of new products or protocols for enhancing production of specific compounds




The New Science of Metagenomics


Book Description

Although we can't usually see them, microbes are essential for every part of human life-indeed all life on Earth. The emerging field of metagenomics offers a new way of exploring the microbial world that will transform modern microbiology and lead to practical applications in medicine, agriculture, alternative energy, environmental remediation, and many others areas. Metagenomics allows researchers to look at the genomes of all of the microbes in an environment at once, providing a "meta" view of the whole microbial community and the complex interactions within it. It's a quantum leap beyond traditional research techniques that rely on studying-one at a time-the few microbes that can be grown in the laboratory. At the request of the National Science Foundation, five Institutes of the National Institutes of Health, and the Department of Energy, the National Research Council organized a committee to address the current state of metagenomics and identify obstacles current researchers are facing in order to determine how to best support the field and encourage its success. The New Science of Metagenomics recommends the establishment of a "Global Metagenomics Initiative" comprising a small number of large-scale metagenomics projects as well as many medium- and small-scale projects to advance the technology and develop the standard practices needed to advance the field. The report also addresses database needs, methodological challenges, and the importance of interdisciplinary collaboration in supporting this new field.




Petroleum Microbial Biotechnology: Challenges and Prospects


Book Description

Petroleum hydrocarbons are both a product of, and rich substrate for, microorganisms from across all Domains of life. Rooted deeply in the history of microbiology, hydrocarbons have been studied as sources of carbon and energy for microorganisms for over a century. As global demand for petroleum and its refined products continues to rise, so do challenges associated with environmental pollution, oil well souring, infrastructure corrosion, oil recovery, transport, refining, and upgrading of heavy crude oils and bitumens. Advances in genomics, synthetic biology and metabolic engineering has invigorated interest in petroleum microbial biotechnology as interest grows in technologies for in situ methane production, biodesulfurization and biodenitrogenation, bio-upgrading of heavy crudes, microbial enhanced oil recovery, corrosion control, and biocatalysts for generating value-added products. Given the complexity of the global petroleum industry and the harsh conditions in which it operates, a deeper understanding of the ecophysiology of aerobic and anaerobic microbial communities that have associations with petroleum hydrocarbons is needed if robust technologies are to be deployed successfully. This research topic highlights recent advances in microbial enhanced oil recovery, methanogenic hydrocarbon metabolism and carbon dioxide sequestration, bioremediation, microbiologically influenced corrosion, biodesulfurization, and the application of metagenomics to better understand microbial communities associated with petroleum hydrocarbons.




Microbial Cell Factories Engineering for Production of Biomolecules


Book Description

Microbial Cell Factories Engineering for Production of Biomolecules presents a compilation of chapters written by eminent scientists worldwide. Sections cover major tools and technologies for DNA synthesis, design of biosynthetic pathways, synthetic biology tools, biosensors, cell-free systems, computer-aided design, OMICS tools, CRISPR/Cas systems, and many more. Although it is not easy to find relevant information collated in a single volume, the book covers the production of a wide range of biomolecules from several MCFs, including Escherichia coli, Bacillus subtilis, Pseudomonas putida, Streptomyces, Corynebacterium, Cyanobacteria, Saccharomyces cerevisiae, Pichia pastoris and Yarrowia lipolytica, and algae, among many others. This will be an excellent platform from which scientific knowledge can grow and widen in MCF engineering research for the production of biomolecules. Needless to say, the book is a valuable source of information not only for researchers designing cell factories, but also for students, metabolic engineers, synthetic biologists, genome engineers, industrialists, stakeholders and policymakers interested in harnessing the potential of MCFs in several fields. - Offers basic understanding and a clear picture of various MCFs - Explains several tools and technologies, including DNA synthesis, synthetic biology tools, genome editing, biosensors, computer-aided design, and OMICS tools, among others - Harnesses the potential of engineered MCFs to produce a wide range of biomolecules for industrial, therapeutic, pharmaceutical, nutraceutical and biotechnological applications - Highlights the advances, challenges, and future opportunities in designing MCFs