Targeting Developmental Pathways in Inflammation and Disease
Author : Maria Pia Felli
Publisher : Frontiers Media SA
Page : 291 pages
File Size : 15,40 MB
Release : 2022-01-05
Category : Science
ISBN : 2889719464
Author : Maria Pia Felli
Publisher : Frontiers Media SA
Page : 291 pages
File Size : 15,40 MB
Release : 2022-01-05
Category : Science
ISBN : 2889719464
Author : Uzma Saqib
Publisher : Frontiers Media SA
Page : 240 pages
File Size : 47,31 MB
Release : 2023-08-14
Category : Medical
ISBN : 2832532446
Author : Bharat B. Aggarwal
Publisher : Springer
Page : 489 pages
File Size : 32,59 MB
Release : 2014-05-12
Category : Medical
ISBN : 3034808372
This volume examines in detail the role of chronic inflammatory processes in the development of several types of cancer. Leading experts describe the latest results of molecular and cellular research on infection, cancer-related inflammation and tumorigenesis. Further, the clinical significance of these findings in preventing cancer progression and approaches to treating the diseases are discussed. Individual chapters cover cancer of the lung, colon, breast, brain, head and neck, pancreas, prostate, bladder, kidney, liver, cervix and skin as well as gastric cancer, sarcoma, lymphoma, leukemia and multiple myeloma.
Author : National Research Council
Publisher : National Academies Press
Page : 102 pages
File Size : 36,93 MB
Release : 2006-01-03
Category : Medical
ISBN : 0309180686
Humans coexist with millions of harmless microorganisms, but emerging diseases, resistance to antibiotics, and the threat of bioterrorism are forcing scientists to look for new ways to confront the microbes that do pose a danger. This report identifies innovative approaches to the development of antimicrobial drugs and vaccines based on a greater understanding of how the human immune system interacts with both good and bad microbes. The report concludes that the development of a single superdrug to fight all infectious agents is unrealistic.
Author : Thomas Hunt Morgan
Publisher :
Page : 392 pages
File Size : 49,30 MB
Release : 1926
Category : Genetics
ISBN :
Author : Adriano Rossi
Publisher : Springer Science & Business Media
Page : 246 pages
File Size : 41,9 MB
Release : 2008-03-17
Category : Medical
ISBN : 376437506X
This book provides readers with an up-to-date and comprehensive view on the resolution of inflammation and on new developments in this area, including pro-resolution mediators, apoptosis, macrophage clearance of apoptotic cells, possible novel drug developments.
Author : Christine M. De Nardo
Publisher : Humana
Page : 0 pages
File Size : 50,27 MB
Release : 2013-07-13
Category : Medical
ISBN : 9781627035224
This Methods in Molecular Biology book offers methods for studying inflammasome function, including generation of inflammasome stimuli, monitoring of caspase-1 activity and processing, activation of IL-1β cytokines, plus lab protocols, material lists and tips.
Author : Alexandrina Ferreira Mendes
Publisher : Frontiers Media SA
Page : 255 pages
File Size : 24,72 MB
Release : 2019-02-20
Category :
ISBN : 288945729X
Chronic diseases are increasingly recognized as involving low grade inflammation, that is, a self-perpetuating tissue response to stress caused by exogenous or endogenous triggers, that progressively evokes danger-associated molecular pattern release, ultimately driving tissue damage and loss of function. This response is frequently unapparent clinically, thus the designation "low grade". This eBook comprises nineteen reviews and original articles that provide the most updated knowledge on the causes and roles of this inflammatory response in a variety of diseases and conditions. The editorial that precedes these articles not only summarizes each one, but provides a broader interpretation of the role of inflammation in health and a variety of disease conditions, the underlying mechanisms and the targets more promising for therapy. Finally, it also highlights the most relevant and emerging research topics that are already shaping future directions for the development of more fine-tuned and innovative therapies.
Author : Kamal Dua
Publisher : Springer Nature
Page : 926 pages
File Size : 15,38 MB
Release : 2021-07-02
Category : Medical
ISBN : 9813368276
The book comprehensively reviews and provides detailed insight into the cellular and molecular signalling mechanisms involved in pathophysiology of various respiratory diseases, towards developing effective therapeutic strategies in the management and treatment of lung disease. It also covers promising advances in the field of therapeutics that could lead to novel clinical therapies capable of preventing or reversing the disease features including novel strategies for targeting chronic lung diseases using advanced drug delivery systems. Importantly, the book examines the significance and relevance of the plant extracts and their constituents with therapeutic efficiencies against lung diseases. As such, the book offers a blend of translational, biological, chemical, and drug delivery aspects relevant to respiratory diseases, thus, offering a valuable resource for pulmonologists and translational researchers working in the field of pulmonary biology and respiratory medicine.
Author : David A. Frank
Publisher : Springer Science & Business Media
Page : 358 pages
File Size : 26,61 MB
Release : 2002-12-31
Category : Medical
ISBN : 1402073402
One of the most exciting areas of cancer research now is the development of agents which can target signal transduction pathways that are activated inappropriately in malignant cells. The understanding of the molecular abnormalities which distinguish malignant cells from their normal counterparts has grown tremendously. This volume summarizes the current research on the role that signal transduction pathways play in the pathogenesis of cancer and how this knowledge may be used to develop the next generation of more effective and less toxic anticancer agents. Series Editor comments: "The biologic behavior of both normal and cancer cells is determined by critical signal transduction pathways. This text provides a comprehensive review of the field. Leading investigators discuss key molecules that may prove to be important diagnostic and/or therapeutic targets."