The Onchocerciasis Control Programme in West Africa


Book Description

An analysis of the many factors that have contributed to the striking success of the Onchocerciasis Control Program in West Africa (OCP), a major public health initiative now entering its twenty-first year. Throughout its history, OCP has been distinguished by its large size, the complexity of its operations, the long time frame needed for success, and the degree of commitment required by donors and participating countries alike. The Program has also been distinguished by its explicit aim to eliminate a disease, which has been a major obstacle to socioeconomic development as well as a cause of great disability and suffering. In examining the Program's many successful features, the author, who has directed OCP since late 1980, draws upon extensive personal experience, supported by the results of several external evaluations, to show how international collaboration, careful planning, and well managed field operations can overcome what may seem to be insurmountable obstacles. Throughout this analysis, an effort is made to extract lessons useful in the management of other large public health programs. The book also gives careful attention to managerial principles that will be important when OCP ceases operation and participating countries take over responsibility for the surveillance and management of recrudescence. The book has two parts. Chapters in the first part give a detailed account of the history, structure, operation, and achievements of OCP. Part two, on the management of OCP, explains how sound budgeting, detailed plans, time-limited goals, task-focused training, and careful computation of costs worked to maintain well-organized operations and keep staff motivated and efficient







Water and Sanitation-Related Diseases and the Changing Environment


Book Description

The revised and updated second edition of Water and Sanitation Related Diseases and the Changing Environment offers an interdisciplinary guide to the conditions responsible for water and sanitation related diseases. The authors discuss the pathogens, vectors, and their biology, morbidity and mortality that result from a lack of safe water and sanitation. The text also explores the distribution of these diseases and the conditions that must be met to reduce or eradicate them. The text includes contributions from authorities from the fields of climate change, epidemiology, environmental health, environmental engineering, global health, medicine, medical anthropology, nutrition, population, and public health. Covers the causes of individual diseases with basic information about the diseases and data on the distribution, prevalence, and incidence as well as interconnected factors such as environmental factors. The authors cover access to and maintenance of clean water, and guidelines for the safe use of wastewater, excreta, and grey water, plus examples of solutions. Written for students, and professionals in infectious disease, public health and medicine, chemical and environmental engineering, and international affairs, the second edition of Water and Sanitation Related Diseases and the Changing Environment isa comprehensive resource to the conditions responsible for water and sanitation related diseases.




Neglected Tropical Diseases - Sub-Saharan Africa


Book Description

This book provides an overview on the major neglected tropical diseases (NTDs) occurring in Sub-Saharan Africa, such as Leishmaniasis, Buruli Ulcer and Schistosomiasis. In well-structured chapters epidemiology and biology of these parasitic diseases will be discussed in detail. Further, diagnostics and therapeutic approaches as well as prevention strategies will be reviewed. The book will be of interest to basic researchers and clinicians engaged in infectious disease, tropical medicine, and parasitology, and a must-have for scientists specialized in the characteristics of the Sub-Saharan region.




Riverblindness in Africa


Book Description

The remarkable story of how a large public-private partnership worked to control and defeat riverblindness—a scourge which had devastated rural communities and impeded socioeconomic development throughout much of Sub-Saharan Africa for generations. Riverblindness (onchocerciasis)—a pervasive neglected disease, transmitted by the blackfly, that causes horrific itching, disfigurement, and loss of vision—is also known as "lion's stare" in reference to the fixed, lifeless glare of the eyes blinded by the disease. The disease has destroyed countless lives for generations, particularly in Africa. Its effects are so devastating that the areas where it is most common (large expanses of land around rivers where the fly breeds) end up abandoned as villages move farther and farther away to more arid environments in order to escape the fly-biting, and hence the disease. The disease devastates communities from multiple angles: a large portion of each stricken community's population is disabled, often permanently blind in the prime of life, placing a burden on the rest, and communities' efforts to escape infection force them to move to areas where farming is less productive. To defeat riverblindness would not only release these communities from the heavy toll of the disease, but would also open more fertile areas in Africa to be inhabited, thus alleviating extreme poverty. These were the goals of the World Bank, led by then-president Robert McNamara, when launching a partnership to combat riverblindness more than forty-five years ago. In this book, Bruce Benton tells the remarkable story of that partnership's success. An authoritative account of the launch and scale-up of the effort, the book covers the transformation of the fight from a top-down high-tech operation to a grassroots drug treatment program covering all of endemic Africa. How, Benton asks, did the effort become such a unique partnership of UN agencies, donors, NGOs, a major pharmaceutical company, universities, African governments, and the stricken communities themselves? Highlighting the importance of disease control in alleviating absolute poverty and promoting development, Benton examines the key developments, individuals, and notable qualities of the partnership in realizing success. He also extracts lessons from this particular story for addressing future challenges through partnership. Drawing on Benton's twenty years of experience managing the riverblindness program for the World Bank, along with extensive research and interviews with 100+ players in the program, Riverblindness in Africa is the first and only book of its kind. The story of the battle has an epic scale, both in terms of geography and the vast number of people and organizations involved. It provides a template for a broad range of global health efforts and is an excellent example of evolving, increasingly effective approaches to disease control and elimination.







Ten years in public health 2007-2017


Book Description

Ten years in public health 2007-2017 chronicles the evolution of global public health over the decade that Margaret Chan served as Director-General at the World Health Organization. This series of chapters evaluates successes setbacks and enduring challenges during the decade. They show what needs to be done when progress stalls or new threats emerge. The chapters show how WHO technical leadership can get multiple partners working together in tandem under coherent strategies. The importance of country leadership and community engagement is stressed repeatedly throughout the chapters. Together we have made tremendous progress. Health and life expectancy have improved nearly everywhere. Millions of lives have been saved. The number of people dying from malaria and HIV has been cut in half. WHO efforts to stop TB saved 49 million lives since the start of this century. In 2015 the number of child deaths dropped below 6 million for the first time a 50% decrease in annual deaths since 1990. Every day 19 000 fewer children die. We are able to count these numbers because of the culture of measurement and accountability instilled in WHO. These chapters tell a powerful story of global challenges and how they have been overcome. In a world facing considerable uncertainty international health development is a unifying – and uplifting – force for the good of humanity.




Entomopathogenic Bacteria: from Laboratory to Field Application


Book Description

Entomopathogenic bacteria (Bacillus thuringiensis and B. sphaericus) are increasingly used as biopesticides to control larval insect populations which are either agricultural or forestry pests and to reduce those which as adults are vectors of severe human diseases. This new book, the first since 1993 to address all aspects of entomopathogenic bacteria, provides undergraduate and graduate students as well as research scientists with a complete, modern view of this important group of bacteria. The authors, chosen for their sustained contributions to the field, cover both fundamental and applied research in this area. The main topics include bacterial ecology and taxonomy, toxin diversity, activity and mode of action, regulation and environment of the genes, safety and ecotoxicology, production and field application of the bacteria, and outbreaks of resistant populations. The book concludes with the most recent data obtained on transgenic biotechnology and addresses environmental impact issues.




Blue Marble Health


Book Description

Why do diseases of poverty afflict more people in wealthy countries than in the developing world? In 2011, Dr. Peter J. Hotez relocated to Houston to launch Baylor’s National School of Tropical Medicine. He was shocked to discover that a number of neglected diseases often associated with developing countries were widespread in impoverished Texas communities. Despite the United States’ economic prowess and first-world status, an estimated 12 million Americans living at the poverty level currently suffer from at least one neglected tropical disease, or NTD. Hotez concluded that the world’s neglected diseases—which include tuberculosis, hookworm infection, lymphatic filariasis, Chagas disease, and leishmaniasis—are born first and foremost of extreme poverty. In this book, Hotez describes a new global paradigm known as “blue marble health,” through which he asserts that poor people living in wealthy countries account for most of the world’s poverty-related illness. He explores the current state of neglected diseases in such disparate countries as Mexico, South Korea, Argentina, Australia, the United States, Japan, and Nigeria. By crafting public policy and relying on global partnerships to control or eliminate some of the world’s worst poverty-related illnesses, Hotez believes, it is possible to eliminate life-threatening disease while at the same time creating unprecedented opportunities for science and diplomacy. Clear, compassionate, and timely, Blue Marble Health is a must-read for leaders in global health, tropical medicine, and international development, along with anyone committed to helping the millions of people who are caught in the desperate cycle of poverty and disease.




Onchocerciasis


Book Description