Author : OECD
Publisher : OECD Publishing
Page : 21 pages
File Size : 31,77 MB
Release : 2002-04-24
Category :
ISBN : 9264070648
This method provides information on health hazard likely to arise from exposure to test substance (liquids, solids and aerosols) by application on the eye. This Test Guideline is intended preferably for use with albino rabbit. The test substance is ...
Author : OECD
Publisher : OECD Publishing
Page : 13 pages
File Size : 10,32 MB
Release : 2023-07-04
Category :
ISBN : 926418533X
This method provides information on health hazard likely to arise from exposure to test substance (liquids, solids and aerosols) by application on the eye. This Test Guideline is intended preferably for use with albino rabbit. The test substance is ...
Author : Organisation for Economic Co-operation and Development
Publisher : Organisation for Economic Co-operation and Development ; [Montréal : Renouf]
Page : pages
File Size : 29,15 MB
Release : 1981
Category : Chemical industry
ISBN : 9789264122215
Author : National Research Council
Publisher : National Academies Press
Page : 450 pages
File Size : 24,11 MB
Release : 1995-09-16
Category : Science
ISBN : 9780309052290
This volume updates and combines two National Academy Press bestsellers--Prudent Practices for Handling Hazardous Chemicals in Laboratories and Prudent Practices for Disposal of Chemicals from Laboratories--which have served for more than a decade as leading sources of chemical safety guidelines for the laboratory. Developed by experts from academia and industry, with specialties in such areas as chemical sciences, pollution prevention, and laboratory safety, Prudent Practices for Safety in Laboratories provides step-by-step planning procedures for handling, storage, and disposal of chemicals. The volume explores the current culture of laboratory safety and provides an updated guide to federal regulations. Organized around a recommended workflow protocol for experiments, the book offers prudent practices designed to promote safety and it includes practical information on assessing hazards, managing chemicals, disposing of wastes, and more. Prudent Practices for Safety in Laboratories is essential reading for people working with laboratory chemicals: research chemists, technicians, safety officers, chemistry educators, and students.
Author : Christoph A. Reinhardt
Publisher : John Wiley & Sons
Page : 200 pages
File Size : 22,2 MB
Release : 2008-11-20
Category : Science
ISBN : 3527616047
Opinion leaders in science and politics examine findings and legislation in alternatives to animal testing! Refine, reduce, replace - These are the three demands that scientists have placed upon themselves in their search for alternatives to animal testing. Indeed much interdisciplinary research is being carried on today, and new fields have emerged, such as in-vitro toxicology. The three R's call for new scientific insights. Moreover, validation and acceptance strategies have to be adapted, a process of much ongoing interest and vital concern to the pharmaceutical and cosmetic industries. Researchers need to know exactly what has been achieved and accepted in alternatives to animal testing in science and politics. In this book they have the opportunity to benefit from the knowledge and expertise of leading researchers and influential representatives of national and international regulatory authorities.
Author : Mr. Khushal B. Chaudhari, Dr. Yogesh V. Ushir
Publisher : Shashwat Publication
Page : 153 pages
File Size : 50,86 MB
Release : 2024-09-28
Category : Medical
ISBN : 9360879711
This book, Practical Pharmacology-III for B.Pharm students, covers all the practical aspects of Pharmacology-III in the PCI syllabus. It focuses on the preclinical screening methods, OECD guidelines for toxicity testing in animals, bioassays and biostatistical calculations.
Author : OECD
Publisher : OECD Publishing
Page : 14 pages
File Size : 33,16 MB
Release : 2002-02-08
Category :
ISBN : 926407094X
A principle of the method is that in the main study only moderately toxic doses are used, and the administration of doses that are expected to be lethal should be avoided. This Guideline is intended primarily for use with rat. Groups of animals of a ...
Author : Rakesh Kumar Tekade
Publisher : Elsevier
Page : 754 pages
File Size : 35,42 MB
Release : 2023-03-23
Category : Medical
ISBN : 044315841X
Toxicity and Toxicodynamics, Volume One in the Essentials of Pharmatoxicology in Drug Research series provides an overview on the essentials of toxicology, risk assessment and the mechanisms. Topics discussed include the types of cellular responses to chemical toxicants, mechanisms of drug toxicity, and their relevance to pharmaceutical product development. The book examines omics and computer-aided technologies for mechanistic and predictive toxicology and covers state-of-art testing in the evaluation of detrimental pathways, dose selection in toxicity studies, as well as the role of regulatory agencies in toxicity studies. In addition, there is also discussion on clinical interventions such as pharmacotherapy and managed care strategies for acute poisoning. This volume is a valuable resource to those learning more about the drug development process related to toxicology and those who want to get an update on newer concepts on the toxicology aspect of drug research. - Examines toxicological risk assessment in drug research - Discusses toxicity mechanisms - Covers risk assessment and the use of omics and computational technologies in mechanistic and predictive toxicology - Offers clinical interventions and managed care as a result of toxic injury and acute poisoning
Author :
Publisher :
Page : 442 pages
File Size : 25,97 MB
Release : 2012-06
Category : Delegated legislation
ISBN :
Author : Kathryn Bayne
Publisher : Academic Press
Page : 335 pages
File Size : 46,13 MB
Release : 2013-09-02
Category : Medical
ISBN : 0123851041
Laboratory Animal Welfare provides a comprehensive, up-to-date look into the new science of animal welfare within laboratory research. Animals specifically considered include rodents, cats and dogs, nonhuman primates, agricultural animals, avian animals and aquatic animals. The book examines the impact of experiment design and environment on animal welfare, as well as emergency situations and euthanasia practices. Readers will benefit from a review of regulations and policy guidelines concerning lab animal use, as well as information on assessing animal welfare. With discussions of the history and ethics of animals in research, and a debate on contemporary and international issues, this book is a go-to resource for laboratory animal welfare.
