The Advance of Neuroscience


Book Description

Neuroscience, like psychology, has a short history but a long past. Although the mind-body relationship has been studied for a long time, it is only in the last fifty years that the term "neuroscience" has been applied to the academic disciplines focusing on brain and behavior. This book explores topics on the brain, psychoactive drugs, and a variety of human behaviors and experiences--such as music and sleep--taking into consideration the importance of historical roots of neuroscience, which have been largely unexamined before now. It looks particularly at the importance of the Victorian era in the development of theories of the nervous system, which are still visible in today's discourse on brain and behavior.




Foundations of Neuroscience


Book Description

The author makes a unique contribution to the field by discussing the history and philosophy of the neurosciences, and then developing critical approaches which integrate techniques, theory, and ethics. Taken as a whole, Jacobson's work will provide a coherent and humane framework for future research programs. The paperback edition of this highly successful text, first published in 1993, is now available! The author brings the ethics of neuroscience into a closer relationship with empirical research. Covering the field's history, philosophy, theories, and techniques, this volume provides the necessary moral and ethical framework to evaluate neuroscience research.




Neuroscience of Nicotine


Book Description

Neuroscience of Nicotine: Mechanisms and Treatment presents the fundamental information necessary for a thorough understanding of the neurobiological underpinnings of nicotine addiction and its effects on the brain. Offering thorough coverage of all aspects of nicotine research, treatment, policy and prevention, and containing contributions from internationally recognized experts, the book provides students, early-career researchers, and investigators at all levels with a fundamental introduction to all aspects of nicotine misuse. With an estimated one billion individuals worldwide classified as tobacco users—and tobacco use often being synonymous with nicotine addiction—nicotine is one of the world's most common addictive substances, and a frequent comorbidity of misuse of other common addictive substances. Nicotine alters a variety of neurological processes, from molecular biology, to cognition, and quitting is exceedingly difficult because of the number of withdrawal symptoms that accompany the process. - Integrates cutting-edge research on the pharmacological, cellular and molecular aspects of nicotine use, along with its effects on neurobiological function - Discusses nicotine use as a component of dual-use and poly addictions and outlines numerous screening and treatment strategies for misuse - Covers both the physical and psychological effects of nicotine use and withdrawal to provide a fully-formed view of nicotine dependency and its effects




Psychiatry and Clinical Neuroscience


Book Description

Research in neuroscience is revolutionizing how we think about psychiatric diagnosis and treatment. Psychiatric disorders reflect dysfunction of the human mind and involve changes in cognition, emotion, and motivation. Understanding how the neural networks that underlie these mental functions become dysfunctional holds great promise for devising innovative approaches to diagnosis and treatment. Scientific progress is being driven, in part, by advances in human functional neuroimaging, which is being used to characterize the activity of specific brain circuits at rest and during the performance of specific tasks. Moreover, advances in clinical neuroscience are being coupled with expanding knowledge about genetics and cellular and synaptic neuroscience. Taken together, these advancements offer the hope of much more mechanism-based approaches to treatment in the future. Better understanding of neural circuits also can provide the basis for innovative psychotherapeutic strategies that take advantage of brain plasticity for purposes of neurorehabilitation. In this book, we examine recent developments in the field of network neuroscience and their potential impact on clinical psychiatry, including the way that psychiatrists are trained and interact with other medical specialties and mental health professionals.




Emergent Neural Computational Architectures Based on Neuroscience


Book Description

It is generally understood that the present approachs to computing do not have the performance, flexibility, and reliability of biological information processing systems. Although there is a comprehensive body of knowledge regarding how information processing occurs in the brain and central nervous system this has had little impact on mainstream computing so far. This book presents a broad spectrum of current research into biologically inspired computational systems and thus contributes towards developing new computational approaches based on neuroscience. The 39 revised full papers by leading researchers were carefully selected and reviewed for inclusion in this anthology. Besides an introductory overview by the volume editors, the book offers topical parts on modular organization and robustness, timing and synchronization, and learning and memory storage.




Handbook of Developmental Cognitive Neuroscience, second edition


Book Description

The second edition of an essential resource to the evolving field of developmental cognitive neuroscience, completely revised, with expanded emphasis on social neuroscience, clinical disorders, and imaging genomics. The publication of the second edition of this handbook testifies to the rapid evolution of developmental cognitive neuroscience as a distinct field. Brain imaging and recording technologies, along with well-defined behavioral tasks—the essential methodological tools of cognitive neuroscience—are now being used to study development. Technological advances have yielded methods that can be safely used to study structure-function relations and their development in children's brains. These new techniques combined with more refined cognitive models account for the progress and heightened activity in developmental cognitive neuroscience research. The Handbook covers basic aspects of neural development, sensory and sensorimotor systems, language, cognition, emotion, and the implications of lifelong neural plasticity for brain and behavioral development. The second edition reflects the dramatic expansion of the field in the seven years since the publication of the first edition. This new Handbook has grown from forty-one chapters to fifty-four, all original to this edition. It places greater emphasis on affective and social neuroscience—an offshoot of cognitive neuroscience that is now influencing the developmental literature. The second edition also places a greater emphasis on clinical disorders, primarily because such research is inherently translational in nature. Finally, the book's new discussions of recent breakthroughs in imaging genomics include one entire chapter devoted to the subject. The intersection of brain, behavior, and genetics represents an exciting new area of inquiry, and the second edition of this essential reference work will be a valuable resource for researchers interested in the development of brain-behavior relations in the context of both typical and atypical development.




Decision Neuroscience


Book Description

Decision Neuroscience addresses fundamental questions about how the brain makes perceptual, value-based, and more complex decisions in non-social and social contexts. This book presents compelling neuroimaging, electrophysiological, lesional, and neurocomputational models in combination with hormonal and genetic approaches, which have led to a clearer understanding of the neural mechanisms behind how the brain makes decisions. The five parts of the book address distinct but inter-related topics and are designed to serve both as classroom introductions to major subareas in decision neuroscience and as advanced syntheses of all that has been accomplished in the last decade. Part I is devoted to anatomical, neurophysiological, pharmacological, and optogenetics animal studies on reinforcement-guided decision making, such as the representation of instructions, expectations, and outcomes; the updating of action values; and the evaluation process guiding choices between prospective rewards. Part II covers the topic of the neural representations of motivation, perceptual decision making, and value-based decision making in humans, combining neurcomputational models and brain imaging studies. Part III focuses on the rapidly developing field of social decision neuroscience, integrating recent mechanistic understanding of social decisions in both non-human primates and humans. Part IV covers clinical aspects involving disorders of decision making that link together basic research areas including systems, cognitive, and clinical neuroscience; this part examines dysfunctions of decision making in neurological and psychiatric disorders, such as Parkinson's disease, schizophrenia, behavioral addictions, and focal brain lesions. Part V focuses on the roles of various hormones (cortisol, oxytocin, ghrelin/leptine) and genes that underlie inter-individual differences observed with stress, food choices, and social decision-making processes. The volume is essential reading for anyone interested in decision making neuroscience. With contributions that are forward-looking assessments of the current and future issues faced by researchers, Decision Neuroscience is essential reading for anyone interested in decision-making neuroscience. - Provides comprehensive coverage of approaches to studying individual and social decision neuroscience, including primate neurophysiology, brain imaging in healthy humans and in various disorders, and genetic and hormonal influences on decision making - Covers multiple levels of analysis, from molecular mechanisms to neural-systems dynamics and computational models of how we make choices - Discusses clinical implications of process dysfunctions, including schizophrenia, Parkinson's disease, eating disorders, drug addiction, and pathological gambling - Features chapters from top international researchers in the field and full-color presentation throughout with numerous illustrations to highlight key concepts




Neuroscience of Rule-Guided Behavior


Book Description

Rules are central to human behaviour, but until now the field of neuroscience lacked a unified approach to understanding them. This book brings together the world's leading cognitive and systems neuroscientists to explain the most recent research on rule-guided behaviour.




NeuroScience Fiction


Book Description

What if science fiction stopped being fiction? Developments in neuroscience are turning sci-fi scenarios into reality, and causing us to revisit some of the philosophical questions we have been asking ourselves for centuries. Science fiction often takes its inspiration from the latest science . . . and our oldest questions. After all, the two are inextricably linked. At a time when advances in artificial intelligence are genuinely leading us closer to a computer that thinks like a human, we can't help but wonder: What makes a person a person? Countless writers and filmmakers have created futuristic scenarios to explore this issue and others like it. But these scenarios may not be so futuristic after all. In the movie Inception, a group of conspirators implants false memories; in Until the End of the World, a mad scientist is able to read dreams; in 2001: A Space Odyssey, a supercomputer feels and thinks like a person. And in recent years, the achievements described in leading scientific journals have included some that might sound familiar: implanting memories using optogenetics, reading the mind during sleep thanks to advanced decoding algorithms, and creating a computer that uses deep neural networks to surpass the abilities of human thought. In NeuroScience Fiction, neuroscientist and author Rodrigo Quiroga reveals the futuristic present we are living in, showing how the far-out premises of 10 seminal science fiction movies are being made possible by discoveries happening right now, on the cutting edge of neuroscience. He also explores the thorny philosophical problems raised as a result, diving into Minority Report and free will, The Matrix and the illusion of reality, Blade Runner and android emotion, and more. A heady mix of science fiction, neuroscience, and philosophy, NeuroScience Fiction takes us from Vanilla Sky to neural research labs, and from Planet of the Apes to what makes us human. This is a book you'll be thinking about long after the last page—and once you've read it, you'll never watch a sci-fi blockbuster the same way again.




Virtual Reality in Behavioral Neuroscience: New Insights and Methods


Book Description

Virtual Reality (VR) is a rapidly maturing technology that offers new and unique solutions to otherwise intractable problems in the study of cognition, behavior and neuroscience. VR removes many of the constraints imposed by laboratory paradigms, allowing us to track cognitive, behavioral and brain responses to naturalistic (or even impossible) situations without sacrificing experimental control. But VR is not a tool that can be swiftly and effortlessly integrated into existing research pipelines; currently, the benefits of VR are accompanied by a host of methodological challenges and important practical considerations. To help navigate this new methodology, this volume provides a balanced review of both the exciting new findings emerging from VR labs and the challenges and limitations that are part and parcel of VR research. This volume is an important first step toward establishing a standardised methodology for conducting research in VR. To this end, the volume provides a wealth of practical advice for researchers who are new to the technology. This volume is authored by an interdisciplinary team of VR researchers including computer scientists, engineers, psychologists and neuroscientists. It highlights current research in the field to demonstrate how VR advances our understanding of the mind, while also providing groundbreaking solutions in applied domains.