Micro-, Meso- and Macro-Connectomics of the Brain


Book Description

This book has brought together leading investigators who work in the new arena of brain connectomics. This includes ‘macro-connectome’ efforts to comprehensively chart long-distance pathways and functional networks; ‘micro-connectome’ efforts to identify every neuron, axon, dendrite, synapse, and glial process within restricted brain regions; and ‘meso-connectome’ efforts to systematically map both local and long-distance connections using anatomical tracers. This book highlights cutting-edge methods that can accelerate progress in elucidating static ‘hard-wired’ circuits of the brain as well as dynamic interactions that are vital for brain function. The power of connectomic approaches in characterizing abnormal circuits in the many brain disorders that afflict humankind is considered. Experts in computational neuroscience and network theory provide perspectives needed for synthesizing across different scales in space and time. Altogether, this book provides an integrated view of the challenges and opportunities in deciphering brain circuits in health and disease.




Callosal Agenesis


Book Description

This book is devoted to the description of agenesis of the corpus callosum, a congenital malformation of midline structures in the brain that may be regarded as a natural model of the "split-brain. " First reported by Rei! in 1812, this anomaly has since been described by several investigators. Interest in this malformation was revived in the 1970s by studies of interhemispheric transfer in Bogen and Vogel's commissurotomized patients and the subsequent findings by Sperry that acallosal patients were devoid of the typical disconnection deficits found in patients with surgical transection of the corpus callosum. Since this seminal work, the bulk of neuropsychological research on callosal agenesis has focused on the particulars of interhemispheric transfer and integration. An ever-growing literature has emerged on the subject, attempting to specify the extent and limits of neural plasticity in a nervous system that has evolved in the absence of the most important interhemispheric pathway. Whilst callosal agenesis proves to be an excellent model of cerebral plasticity, it has to be pointed out that this anomaly is often associated with other malformations and neurological diseases that may result in different degrees of mental retardation or other cognitive and sensorimotor deficits. In this context, neurological research on callosal agenesis has concentrated on the description of various syndromes associated with this pathology as well as on the attempt to specify its neurobehavioral manifestations.




The Parallel Brain


Book Description

An overview of the central role in cognitive neuroscience of the corpus callosum, the bands of tissue connecting the brain's two hemispheres.




Discovering the Brain


Book Description

The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a "field guide" to the brainâ€"an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines: How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attentionâ€"and how a "gut feeling" actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the "Decade of the Brain," with a look at medical imaging techniquesâ€"what various technologies can and cannot tell usâ€"and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakersâ€"and many scientists as wellâ€"with a helpful guide to understanding the many discoveries that are sure to be announced throughout the "Decade of the Brain."




Agenesis of the Corpus Callosum


Book Description

This book contains information about Agenesis of the Corpus Callosum and various medical terminology that goes along with this condition. It is a beneficial tool for those who have this disease or for anyone who wants to learn about it.




Encyclopedia of Language Development


Book Description

The progression from newborn to sophisticated language user in just a few short years is often described as wonderful and miraculous. What are the biological, cognitive, and social underpinnings of this miracle? What major language development milestones occur in infancy? What methodologies do researchers employ in studying this progression? Why do some become adept at multiple languages while others face a lifelong struggle with just one? What accounts for declines in language proficiency, and how might such declines be moderated? Despite an abundance of textbooks, specialized monographs, and a couple of academic handbooks, there has been no encyclopedic reference work in this area--until now. The Encyclopedia of Language Development covers the breadth of theory and research on language development from birth through adulthood, as well as their practical application. Features: This affordable A-to-Z reference includes 200 articles that address such topic areas as theories and research tradition; biological perspectives; cognitive perspectives; family, peer, and social influences; bilingualism; special populations and disorders; and more. All articles (signed and authored by key figures in the field) conclude with cross reference links and suggestions for further reading. Appendices include a Resource Guide with annotated lists of classic books and articles, journals, associations, and web sites; a Glossary of specialized terms; and a Chronology offering an overview and history of the field. A thematic Reader’s Guide groups related articles by broad topic areas as one handy search feature on the e-Reference platform, which includes a comprehensive index of search terms. Available in both print and electronic formats, Encyclopedia of Language Development is a must-have reference for researchers and is ideal for library reference or circulating collections. Key Themes: Categories Effects of language on cognitive development Fundamentals, theories and models of language development Impairments of language development Language development in special populations Literacy and language development Mechanisms of language development Methods in language development research Prelinguistic communicative development Social effects in language acquisition Specific aspects of language development




Localization of Brain Lesions and Developmental Functions


Book Description

The study of neuropsychological functions in children has lately undergone a considerable evolution, most obviously represented by the evidence that cerebral areas of the child's brain are specialised at a very early stage. Such evidence has been derived from a number of anatomical, physiological and clinical studies. This book examines and defines the pictures of any deficient function, or of several, in relation to lesions of different cerebral areas, thereby indirectly demonstrating the role of these areas in neuropsychological development.




High-Functioning Individuals with Autism


Book Description

Designed to advance understanding of the unique needs of high-functioning individuals with autism, this volume details the latest diagnostic and treatment approaches and analyzes the current conceptions of the neurological processes involved in autism.




From Neurons to Neighborhoods


Book Description

How we raise young children is one of today's most highly personalized and sharply politicized issues, in part because each of us can claim some level of "expertise." The debate has intensified as discoveries about our development-in the womb and in the first months and years-have reached the popular media. How can we use our burgeoning knowledge to assure the well-being of all young children, for their own sake as well as for the sake of our nation? Drawing from new findings, this book presents important conclusions about nature-versus-nurture, the impact of being born into a working family, the effect of politics on programs for children, the costs and benefits of intervention, and other issues. The committee issues a series of challenges to decision makers regarding the quality of child care, issues of racial and ethnic diversity, the integration of children's cognitive and emotional development, and more. Authoritative yet accessible, From Neurons to Neighborhoods presents the evidence about "brain wiring" and how kids learn to speak, think, and regulate their behavior. It examines the effect of the climate-family, child care, community-within which the child grows.




Tele-AAC


Book Description

Tele-AAC: Augmentative and Alternative Communication Through Telepractice is the first comprehensive resource guide to Tele-AAC. Tele-AAC is the use of telepractice specifically for providing services to individuals using augmentative and alternative communication (AAC). This text establishes Tele-AAC as a new service delivery model and promotes safe, efficacious, evidence-based, and ethical telepractice for individuals who need AAC systems. The goal is to provide readers with fundamental information about policy and service delivery of AAC services via telepractice to enable clinical practice. The text details the specific technical components unique to Tele-AAC service delivery, and how the technology, personnel, and service delivery practices may vary across settings and populations. It offers didactic and case-based content for speech-language pathologists across all levels, from introductory to advanced. Chapters are included that clarify and define the term Tele-AAC, highlight the procedures used while providing assessment and intervention via Tele-AAC, identify ethical and cultural considerations while providing Tele-AAC, and demonstrate its application in a variety of settings. The content has been enriched by the input and knowledge offered by leaders from both telepractice and AAC disciplines, and offers readers the right combination of foundational information and principles to help form a base of understanding for practitioners engaging in Tele-AAC. The field of Tele-AAC is evolving and will transform as the technology changes and advances. This text provides a threshold of understanding from which the field and practitioners can grow.