A Shot to Save the World


Book Description

"An inspiring and informative page-turner." –Walter Isaacson Longlisted for the FT/McKinsey Business Book of the Year Award The authoritative account of the race to produce the vaccines that are saving us all, from the #1 New York Times bestselling author of The Man Who Solved the Market Few were ready when a mysterious respiratory illness emerged in Wuhan, China in January 2020. Politicians, government officials, business leaders, and public-health professionals were unprepared for the most devastating pandemic in a century. Many of the world’s biggest drug and vaccine makers were slow to react or couldn’t muster an effective response. It was up to a small group of unlikely and untested scientists and executives to save civilization. A French businessman dismissed by many as a fabulist. A Turkish immigrant with little virus experience. A quirky Midwesterner obsessed with insect cells. A Boston scientist employing questionable techniques. A British scientist despised by his peers. Far from the limelight, each had spent years developing innovative vaccine approaches. Their work was met with skepticism and scorn. By 2020, these individuals had little proof of progress. Yet they and their colleagues wanted to be the ones to stop the virus holding the world hostage. They scrambled to turn their life’s work into life-saving vaccines in a matter of months, each gunning to make the big breakthrough—and to beat each other for the glory that a vaccine guaranteed. A #1 New York Times bestselling author and award-winning Wall Street Journal investigative journalist lauded for his “bravura storytelling” (Gary Shteyngart) and “first-rate” reporting (The New York Times), Zuckerman takes us inside the top-secret laboratories, corporate clashes, and high-stakes government negotiations that led to effective shots. Deeply reported and endlessly gripping, this is a dazzling, blow-by-blow chronicle of the most consequential scientific breakthrough of our time. It’s a story of courage, genius, and heroism. It’s also a tale of heated rivalries, unbridled ambitions, crippling insecurities, and unexpected drama. A Shot to Save the World is the story of how science saved the world.




Adverse Effects of Pertussis and Rubella Vaccines


Book Description

Parents have come to depend on vaccines to protect their children from a variety of diseases. Some evidence suggests, however, that vaccination against pertussis (whooping cough) and rubella (German measles) is, in a small number of cases, associated with increased risk of serious illness. This book examines the controversy over the evidence and offers a comprehensively documented assessment of the risk of illness following immunization with vaccines against pertussis and rubella. Based on extensive review of the evidence from epidemiologic studies, case histories, studies in animals, and other sources of information, the book examines: The relation of pertussis vaccines to a number of serious adverse events, including encephalopathy and other central nervous system disorders, sudden infant death syndrome, autism, Guillain-Barre syndrome, learning disabilities, and Reye syndrome. The relation of rubella vaccines to arthritis, various neuropathies, and thrombocytopenic purpura. The volume, which includes a description of the committee's methods for evaluating evidence and directions for future research, will be important reading for public health officials, pediatricians, researchers, and concerned parents.




Revelation


Book Description

The final book of the Bible, Revelation prophesies the ultimate judgement of mankind in a series of allegorical visions, grisly images and numerological predictions. According to these, empires will fall, the "Beast" will be destroyed and Christ will rule a new Jerusalem. With an introduction by Will Self.




Shot in the Heart


Book Description

NATIONAL BOOK CRITICS CIRCLE AWARD WINNER • A murder tale "from inside the house where murder is born." Haunting, harrowing, and profoundly affecting, Shot in the Heart exposes and explores a dark vein of American life that most of us would rather ignore. It is a book that will leave no reader unchanged. Gary Gilmore, the infamous murderer immortalized by Norman Mailer in The Executioner's Song, campaigned for his own death and was executed by firing squad in 1977. Writer Mikal Gilmore is his younger brother. In Shot in the Heart, he tells the stunning story of their wildly dysfunctional family: their mother, a black sheep daughter of unforgiving Mormon farmers; their father, a drunk, thief, and con man. It was a family destroyed by a multigenerational history of child abuse, alcoholism, crime, adultery, and murder. Mikal, burdened with the guilt of being his father's favorite and the shame of being Gary's brother, gracefully and painfully relates his story "from inside the house where murder is born... a house that, in some ways, [he has] never been able to leave." Shot in the Heart is the history of an American family inextricably tied up with violence, and the story of how the children of this family committed murder and murdered themselves in payment for a long lineage of ruin.




Who Shot the President?


Book Description

/Judy Donnelly Judy Donnelly recounts that fateful day in Dallas when the nation witnessed the assassination of its youngest president, John F. Kennedy. Black-and-white photos.




Immunization Safety Review


Book Description

With current recommendations calling for infants to receive multiple doses of vaccines during their first year of life and with sudden infant death syndrome (SIDS) the most frequent cause of death during the postneonatal period, it is important to respond to concerns that vaccination might play a role in sudden unexpected infant death. The committee reviewed epidemiologic evidence focusing on three outcomes: SIDS, all SUDI (sudden unexpected death in infancy), and neonatal death (infant death, whether sudden or not, during the first 4 weeks of life). Based on this review, the committee concluded that the evidence favors rejection of a causal relationship between some vaccines and SIDS; and that the evidence is inadequate to accept or reject a causal relationship between other vaccines and SIDS, SUDI, or neonatal death. The evidence regarding biological mechanisms is essentially theoretical, reflecting in large measure the lack of knowledge concerning the pathogenesis of SIDS.




The Death Shot A Story Retold


Book Description

"The Death Shot: A Story Retold" is a gripping story penned by means of Captain Mayne Reid. This adventure novel, written within the nineteenth century, is understood for its vivid storytelling and exploration of themes which include honor, revenge, and the consequences of a fateful choice. The narrative follows the protagonist, Gaston de St. Croix, a young Frenchman looking for justice for the murder of his father. Fueled by way of a desire for revenge, Gaston turns into embroiled in a complex internet of political intrigue, deceit, and private vendettas. The titular "Death Shot" refers to a lethal duel that plays a crucial function in the plot, symbolizing the excessive stakes and ethical dilemmas confronted by means of the characters. Captain Mayne Reid, a prolific creator of journey novels, skillfully weaves together factors of suspense, motion, and romance. "The Death Shot: A Story Retold" not best captivates readers with its thrilling narrative however additionally explores the deeper complexities of human nature and the results of pursuing justice in a international full of moral ambiguity.




Immunization Safety Review


Book Description

The Immunization Safety Review Committee was established by the Institute of Medicine (IOM) to evaluate the evidence on possible causal associations between immunizations and certain adverse outcomes, and to then present conclusions and recommendations. The committee's mandate also includes assessing the broader societal significance of these immunization safety issues. While all the committee members share the view that immunization is generally beneficial, none of them has a vested interest in the specific immunization safety issues that come before the group. The committee reviews three immunization safety review topics each year, addressing each one at a time. In this fifth report in a series, the committee examines the hypothesis that exposure to polio vaccine contaminated with simian virus 40 (SV40), a virus that causes inapparent infection in some monkeys, can cause certain types of cancer.




The Death Shot: A Story Retold


Book Description




The Cutter Incident


Book Description

Vaccines have saved more lives than any other single medical advance. Yet today only four companies make vaccines, and there is a growing crisis in vaccine availability. Why has this happened? This remarkable book recounts for the first time a devastating episode in 1955 at Cutter Laboratories in Berkeley, California, thathas led many pharmaceutical companies to abandon vaccine manufacture. Drawing on interviews with public health officials, pharmaceutical company executives, attorneys, Cutter employees, and victims of the vaccine, as well as on previously unavailable archives, Dr. Paul Offit offers a full account of the Cutter disaster. He describes the nation's relief when the polio vaccine was developed by Jonas Salk in 1955, the production of the vaccine at industrial facilities such as the one operated by Cutter, and the tragedy that occurred when 200,000 people were inadvertently injected with live virulent polio virus: 70,000 became ill, 200 were permanently paralyzed, and 10 died. Dr. Offit also explores how, as a consequence of the tragedy, one jury's verdict set in motion events that eventually suppressed the production of vaccines already licensed and deterred the development of new vaccines that hold the promise of preventing other fatal diseases.