› › The Development Of Micro And Nano Particulate Delivery Systems For Vaccines Using Supercritical Fluid Technology

Drug Delivery Systems: Advanced Technologies Potentially Applicable in Personalised Treatment

Author : Jorge Coelho

Publisher : Springer Science & Business Media

Page : 433 pages

File Size : 47,50 MB

Release : 2013-03-15

Category : Medical

ISBN : 9400760108

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Book Description

This book is part of a series dedicated to recent advances on preventive, predictive and personalised medicine (PPPM). It focuses on the theme of “Drug delivery systems: advanced technologies potentially applicable in personalised treatments”. The critical topics involving the development and preparation of effective drug delivery systems, such as: polymers available, self-assembly, nanotechnology, pharmaceutical formulations, three dimensional structures, molecular modeling, tailor-made solutions and technological tendencies, are carefully discussed. The understanding of these areas constitutes a paramount route to establish personalised and effective solutions for specific diseases and individuals.



Nanoparticulate Drug Delivery Systems

Author : Deepak Thassu

Publisher : CRC Press

Page : 317 pages

File Size : 32,51 MB

Release : 2007-03-30

Category : Medical

ISBN : 1000654745

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Book Description

With the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. Nanoparticulate Drug Delivery Systems addresses the scientific methodologies, formulation, processing, applications, recent trends, and e



Recent Advances in Novel Drug Carrier Systems

Author : Ali Demir Sezer

Publisher : BoD – Books on Demand

Page : 516 pages

File Size : 17,10 MB

Release : 2012-10-31

Category : Medical

ISBN : 9535108107

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Book Description

This contribution book collects reviews and original articles from eminent experts working in the interdisciplinary arena of novel drug delivery systems and their uses. From their direct and recent experience, the readers can achieve a wide vision on the new and ongoing potentialities of different drug delivery systems. Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. On the other hand, this reference discusses advances in the design, optimization, and adaptation of gene delivery systems for the treatment of cancer, cardiovascular, pulmonary, genetic, and infectious diseases, and considers assessment and review procedures involved in the development of gene-based pharmaceuticals.



Strategies to Modify the Drug Release from Pharmaceutical Systems

Author : Marcos Luciano Bruschi

Publisher : Woodhead Publishing

Page : 208 pages

File Size : 16,51 MB

Release : 2015-06-16

Category : Medical

ISBN : 0081001126

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Book Description

Since the earliest dosage forms to modern drug delivery systems, came a great development and growth of knowledge with respect to drug delivery. Strategies to Modify the Drug Release from Pharmaceutical Systems will address principles, systems, applications and advances in the field.It will be principally a textbook and a reference source of strategies to modify the drug release. Moreover, the characterization, mathematical and physicochemical models, applications and the systems will be discussed. - Addresses the principles, systems, applications and advances in the field of drug delivery - Highlights the mathematical and physicochemical principles related to strategies - Discusses drug release and its possible modifications



Vaccine Design

Author : Michael F. Powell

Publisher : Springer

Page : 977 pages

File Size : 30,48 MB

Release : 2012-12-06

Category : Medical

ISBN : 1461518237

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Book Description

When my interest was first drawn to the phenomenon of vaccination for virus diseases in the late 1930s, the state of the art and the science of vaccine design was not far advanced beyond the time of Jenner at the end of the 18th century and of Pasteur a century later. In the 1930s it was still believed that for the induction of immunity to a virus-caused disease the experience of infection was required, but not for a toxin-caused disease such as diphtheria or tetanus, for which a chemically detoxified antigen was effective for immu nization. This prompted the question as to whether it might be possible to produce a similar effect for virus diseases using nonreplicating antigens. When in the 1930s and 1940s it was found possible to propagate influenza viruses in the chick embryo, protective effects could be induced without the need to experience infection by the use of a sufficient dose of a noninfectious influenza virus preparation. Later in the 1940s, it became possible to propagate polio and other viruses in cultures of human and monkey tissue and to immunize against other virus diseases in the same way. Later, with the advent of the era of molecular biology and genetic engineering, antigens and vaccines could be produced in new and creative ways, using either replicating or nonreplicating forms of the appropriate antigens for inducing a dose-related protective state.



Nanotechnology in Drug Delivery

Author : Melgardt M. de Villiers

Publisher : Springer Science & Business Media

Page : 681 pages

File Size : 35,33 MB

Release : 2008-10-29

Category : Medical

ISBN : 0387776680

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Book Description

The reader will be introduced to various aspects of the fundamentals of nanotechnology based drug delivery systems and the application of these systems for the delivery of small molecules, proteins, peptides, oligonucleotides and genes. How these systems overcome challenges offered by biological barriers to drug absorption and drug targeting will also be described.



Vaccine Adjuvants and Delivery Systems

Author : Manmohan Singh

Publisher : John Wiley & Sons

Page : 470 pages

File Size : 38,29 MB

Release : 2007-08-03

Category : Science

ISBN : 0470134925

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Book Description

The authoritative reference on recent developments in vaccinology New technologies, including recombinant protein and DNA, have sparked phenomenal progress in vaccine development and delivery systems. This unique resource brings scientists up to date on recent advances and provides the information they need to select candidate adjuvants. With chapters written by leading experts in their fields, Vaccine Adjuvants and Delivery Systems: * Provides a comprehensive overview of the rapidly evolving field and developing formulation methods * Covers cutting-edge technologies and gives the current status of adjuvants in clinical trials and those still in the pre-clinical stage * Includes detailed information on specific vaccine adjuvants, including MF59, TLR4 agonists, new iscoms, cytokines, polyphosphazenes, and more * Provides a historical perspective on the development of vaccine adjuvants and discusses the mechanisms of adjuvant actions * Covers some novel adjuvants and delivery systems and the safety evaluation of adjuvants A great reference for researchers, scientists, and students in vaccinology, biotechnology, immunology, and molecular biology, this resource is also valuable for researchers and scientists in veterinary medicine who work to prevent diseases in animals.



3D Printed Microfluidic Devices

Author : Savas Tasoglu

Publisher : MDPI

Page : 213 pages

File Size : 13,32 MB

Release : 2019-01-10

Category : Technology & Engineering

ISBN : 3038974676

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Book Description

This book is a printed edition of the Special Issue "3D Printed Microfluidic Devices" that was published in Micromachines



Smart Drug Delivery System

Author : Ali Demir Sezer

Publisher : BoD – Books on Demand

Page : 400 pages

File Size : 46,99 MB

Release : 2016-02-10

Category : Medical

ISBN : 9535122479

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Book Description

This contribution book collects reviews and original articles from eminent experts working in the interdisciplinary arena of novel drug delivery systems and their uses. From their direct and recent experience, the readers can achieve a wide vision on the new and ongoing potentialities of different smart drug delivery systems. Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. On the other hand, this reference discusses advances in the design, optimization, and adaptation of gene delivery systems for the treatment of cancer, cardiovascular, diabetic, genetic, and infectious diseases, and considers assessment and review procedures involved in the development of gene-based pharmaceuticals.



Delivery Technologies for Biopharmaceuticals

Author : Lene Jorgensen

Publisher : John Wiley & Sons

Page : 442 pages

File Size : 16,68 MB

Release : 2009-10-23

Category : Science

ISBN : 0470688408

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Book Description

Advances in biotechnology have provided scientists with an increasing number of biopharmaceuticals such as novel peptide and protein drugs as well as nucleic acid based drugs for gene therapy. However, successful delivery of these biopharmaceuticals is a major challenge because their molecular properties lead to poor physical and chemical stability in the body and limited membrane permeability. Therefore researchers are developing a range of new delivery technologies and materials to enable these new drugs to be delivered intact to their target sites. Delivery Technologies for Biopharmaceuticals describes strategies to overcome the main barriers for successful delivery of therapeutic peptides, proteins, and nucleic acid-based drugs or vaccines related to the site of administration and the target site. Many of the approaches described are reported in formulations in current clinical trials as well as in marketed products. Contents include: challenges in delivery of biopharmaceuticals novel formulation approaches for peptide and protein injectables non-viral chemical vectors and viral technology for delivery of nucleic acid based drugs immune response, adjuvants and delivery systems for vaccines several examples of delivery systems for different biopharmaceuticals a critical assessment of delivery technologies for biopharmaceuticals Delivery Technologies for Biopharmaceuticals is an essential single-volume introduction to the technologies used by researchers to ensure efficient delivery of this exciting new class of drugs. It will be of value to researchers and students working in drug delivery, formulation, biopharmaceuticals, medicinal chemistry, and new materials development.