The Effect of a Worldwide Pandemic on the Global Production and Supply Chain of Pharmaceuticals


Book Description

The pharmaceutical industry must handle the supply side cost pressures of the day for profitability. However, increasing efficiencies along its supply chain through company mergers, the consolidation of production sites and the relocation of manufacturing create increasing complexity. It is no coincidence that this has led to an increased dependency on China and India. The COVID-19 pandemic of 2020 is a large threat to pharmaceutical production, transportation, storage, supply and distribution. In recent years, worldwide supply shortages and stockouts for medicinal products have risen, so the COVID-19 pandemic intensifies the potential monetary and social consequences of drug shortages. A thorough understanding of pharmaceutical supply chain structures and the risks in supply chains and their management provide the fundamentals to assess the impact of the pandemic. The pharmaceutical industry is characterized by above-average stock levels to maintain its constant readiness to deliver to society. The German BfArM drug supply database and media reports allow a local analysis of this readiness during the pandemic. Bottlenecks from patient stockpiling and increased occupancy in intensive care units are evident, but the German COVID-19 pandemic has not led to significant supply shortages, indicating that above-average stock levels have ameliorated the e↵ects of the Chinese production cessation in early 2020. It remains unclear whether the consequences of production losses can be completely absorbed by the prevailing stockpiles particularly if the pandemic continues. Up to mid-2020, the pandemic impact has been minimal for the pharmaceutical industry. However, the industry must begin to include risk management strategies in its assessment of efficiency, by considering pandemic scenarios with higher death rates, more dependency on pharmaceuticals and longer periods of quarantine. For affected governments and other companies worldwide, it is clear that more transparency and communication along globalized supply chains is required in order to successfully manage present and future risks.




The Impact of the Covid-19 Pandemic on Global Supply Chains


Book Description

Seminar paper from the year 2023 in the subject Business economics - Supply, Production, Logistics, grade: 5.0, Addis Ababa University, course: Master of Business Management, language: English, abstract: The COVID-19 pandemic profoundly disrupted global supply chains, leading to unprecedented economic challenges and logistical complexities. Originating in China in December 2019, the virus rapidly spread to over 210 countries, resulting in more than 100 million confirmed cases worldwide and over 2 million deaths. This global crisis triggered severe disruptions across various sectors, including high-tech industries, automotive manufacturing, pharmaceuticals, and food supply chains. Notably, companies like Apple, Samsung, and Tesla experienced production halts due to labor shortages and supply chain constraints. Additionally, the pharmaceutical industry grappled with increased demand for essential medical supplies, while the food sector faced labor shortages and transportation disruptions. The pandemic-induced shutdowns, travel restrictions, and stringent import/export controls severely hampered international logistics, further exacerbating supply chain vulnerabilities. Consequently, the crisis highlighted the intricate interdependencies within global supply chains and underscored the urgent need for resilience, sustainability, and strategic reevaluation to mitigate future disruptions effectively.




Science-Based Approaches to Respond to COVID and Other Public Health Threats


Book Description

COVID-19 and other public health threats have contributed to more than six million deaths globally in a short amount of time. As such, there is an urgent need to respond to these threats in a way that improves global health and wellbeing. Written by a diverse group of exemplary scientists, the thirteen chapters in this volume provide unique, comprehensive, and science-based approaches to respond to macro-structural, human process, and micro issues affecting public health threats.




Supply Chain Management in the Drug Industry


Book Description

This book bridges the gap between practitioners of supply-chain management and pharmaceutical industry experts. It aims to help both these groups understand the different worlds they live in and how to jointly contribute to meaningful improvements in supply-chains within the globally important pharmaceutical sector. Scientific and technical staff must work closely with supply-chain practitioners and other relevant parties to help secure responsive, cost effective and risk mitigated supply chains to compete on a world stage. This should not wait until a drug has been registered, but should start as early as possible in the development process and before registration or clinical trials. The author suggests that CMC (chemistry manufacturing controls) drug development must reset the line of sight – from supply of drug to the clinic and gaining a registration, to the building of a patient value stream. Capable processes and suppliers, streamlined logistics, flexible plant and equipment, shorter cycle times, effective flow of information and reduced waste. All these factors can and should be addressed at the CMC development stage.







Vaccines, Medicines and COVID-19


Book Description

This open access book is a collection of research papers on COVID-19 by Germán Velásquez from 2020 and early 2021 that help to answer the question: How can an agency like the World Health Organization (WHO) be given a stronger voice to exercise authority and leadership? The considerable health, economic and social challenges that the world faced at the beginning of 2020 with COVID-19 continued and worsened in many parts of the world in the second-half of 2020 and into 2021. Many of these countries and nations wanted to explore COVID-19 on their own, sometimes without listening to the main international health bodies such as WHO, an agency of the United Nations system with long-standing experience and vast knowledge at the global level and of which all countries in the world are members. In this single volume, the chapters present the progress of thinking and debate — particularly in relation to drugs and vaccines — that would enable a response to the COVID-19 pandemic or to subsequent crises that may arise. Among the topics covered: COVID-19 Vaccines: Between Ethics, Health and Economics Medicines and Intellectual Property: 10 Years of the WHO Global Strategy Re-thinking Global and Local Manufacturing of Medical Products After COVID-19 Rethinking R&D for Pharmaceutical Products After the Novel Coronavirus COVID-19 Shock Intellectual Property and Access to Medicines and Vaccines The World Health Organization Reforms in the Time of COVID-19 Vaccines, Medicines and COVID-19: How Can WHO Be Given a Stronger Voice? is essential reading for negotiators from the 194 member countries of the World Health Organization (WHO); World Trade Organization (WTO) and World Intellectual Property Organization (WIPO) staff participating in these negotiations; academics and students of public health, medicine, health sciences, law, sociology and political science; and intergovernmental organizations and non-governmental organizations that follow the issue of access to treatments and vaccines for COVID-19.




Managing Supply Chain Risk and Disruptions: Post COVID-19


Book Description

This book summarizes the effect of COVID-19 on the global supply chain. Eminent researchers, practitioners, and professors discuss the challenges faced by supply chain providers and supply chain strategies related to various global, retail, fast moving consumer goods, humanitarian, pharmaceutical, and agricultural supply chains. This book also suggests the resilient approach adopted by supply chain organizations for quick recovery and re-establishing their networks. This book helps the readers explore the pandemic's impact on the supply chain and rebuilding the same using suitable approaches.




Supply Chain Management and Restart of Economy in Post COVID-19


Book Description

The increase in World Trade has led to significant growth in world GDP over last 100 years particularly. Supply chains have become the major enablers of world trade and the world is connected through supply chains. Any disruptions in any part of the world has led to disruptions in supply chains and economic recessions. Crisis like Tsunamis, earthquakes, 911 terror attacks, epidemics/pandemics like COVID-19 etc. have affected the businesses worldwide. COVID-19 pandemic has precipitated economic crisis due to disruption of supply chains and suppressed demand for many products and services worldwide. International Monetary Fund (IMF) has projected global economic growth to be negative 4.9%. This economic crisis has resulted in substantial erosion of market capitalization across the globe. The impact of COVID-19 is very significant on both health of the people and economy worldwide. Almost all businesses and governments are trying its best to save people from health and economic crisis. This requires rebuilding of supply chains through appropriate configuration with reliable sources of supply, collaboration, manufacturing and distribution of goods and services. Sectors like essential items, pharmaceutical, e-commerce have started early recovery of economy. However, other sectors require suitable interventions from government, business organizations in their policies and practices and use of digital technologies for economic recovery.




Economic Policy for a Pandemic Age


Book Description

The global health and economic threats from the COVID-19 pandemic are not yet behind us. While the development of multiple safe and highly effective vaccines in less than a year is cause for hope, several significant dangers to recovery of global health and income are still clear and present: New concerning variants of SARS-CoV-2, the virus that causes COVID-19, continue to emerge at an alarming rate in different parts of the world; at the same time, vaccine rollouts have been shockingly inefficient even in some rich countries, while much of the developing world waits in line behind them for vaccines to arrive. The Briefing covers several policy areas in which cooperative forward-looking policy action will materially improve our chances of truly escaping today's pandemic and making future pandemics less costly.




Global Trends 2040


Book Description

"The ongoing COVID-19 pandemic marks the most significant, singular global disruption since World War II, with health, economic, political, and security implications that will ripple for years to come." -Global Trends 2040 (2021) Global Trends 2040-A More Contested World (2021), released by the US National Intelligence Council, is the latest report in its series of reports starting in 1997 about megatrends and the world's future. This report, strongly influenced by the COVID-19 pandemic, paints a bleak picture of the future and describes a contested, fragmented and turbulent world. It specifically discusses the four main trends that will shape tomorrow's world: - Demographics-by 2040, 1.4 billion people will be added mostly in Africa and South Asia. - Economics-increased government debt and concentrated economic power will escalate problems for the poor and middleclass. - Climate-a hotter world will increase water, food, and health insecurity. - Technology-the emergence of new technologies could both solve and cause problems for human life. Students of trends, policymakers, entrepreneurs, academics, journalists and anyone eager for a glimpse into the next decades, will find this report, with colored graphs, essential reading.