The Haemophilic Joints


Book Description

Edited by an orthopaedic surgeon who is a leading specialist in the treatment of the musculo-skeletal complications of haemophilia.The Haemophilic Joints: New Perspectives reviews the different protocols for the orthopaedic management of the haemophilic articulations. The book draws together, in a single volume, the more recent perspectives of all the orthopaedic methods that can be applied in the diagnosis and treatment of the haemophilic joints from numerous specialists worldwide. It will be an invaluable resource for all those treating the articular problems in people with haemophilia.




Joint Surgery in the Adult Patient with Hemophilia


Book Description

This book provides clear instruction on the surgical treatment of joint problems in adult hemophilia patients. The procedures applicable to specific joints, including the shoulder, elbow, hip, knee and ankle, are carefully reviewed with the aid of high-quality illustrations. The surgical treatment of articular hemophilic pseudotumors and bone cysts is also considered. In addition, clinically relevant information is provided on a range of topics, such as the treatment of hemophilic hemarthrosis, the imaging of hemophilic joints, hematological perioperative management, anesthesia, rehabilitation and pharmacoeconomics. Finally, the controversial issues of postoperative thromboembolic prophylaxis and the role of COX-2 inhibitors in hemophiliacs are reviewed. The guidance provided draws on both the authors’ extensive personal experience and an in-depth review of the pertinent literature. The book offers an excellent, up-to-date account of knowledge on musculoskeletal problems and approaches to joint surgery in adults with hemophilia. It will be of value to orthopedic surgeons, rehabilitation physicians, hematologists, radiologists and pharmacy researchers.




The Management of the Haemophilc Arthropathy


Book Description

Frontiers in Arthritis is an ebook series devoted to publishing the latest advances in arthritis medicine and research. Each volume brings forth contributions on topics relevant to the diagnosis, management and treatment of arthritis. The ebook series is essential reading for rheumatologists and orthopedic surgeons involved in clinical research and practice. This volume presents comprehensive information about the pathology, diagnosis and treatment of haemophilic arthropathy. Readers will find information about knee, hip, elbow, foot and ankle surgery in patients affected by haemophilia as well as special topics (microsurgery and postoperative rehabilitation and health risks). The broad range of information presented in this volume makes it the definitive handbook on arthritis in haemophiliac cases and the management of related complications.




Current and Future Issues in Hemophilia Care


Book Description

As haemophilia is a life-long condition, continuing supervision by a group of medical personnel is required. In many countries this is provided by comprehensive care haemophilia centres where staff of all specialities concerned with treatment- haematologists, paediatricians, nurses, physiotherapists, orthopaedic surgeons - have specialized knowledge. This new book is a definitive resource on the current aspects and issues around haemophilia. Complications of haemophilia care are well covered in chapters on inhibitors, and musculoskeletal problems, as are all the latest developments in the field of haemophilia.







Musculoskeletal Aspects of Haemophilia


Book Description

Edited by two leading orthopaedic surgeons specializing in the treatment of haemophilia, and an acclaimed haematologist, Musculoskeletal Aspects of Haemophilia draws together, within a single volume, all the information needed for the practical treatment of the musculoskeletal complications of haemophilia. A practical 'hands on' guide designed for use on the ward, in the office and at the computer, this book draws on the experience not only of two major centres (Madrid, Spain and London, UK) but also of numerous specialists worldwide. In addition to orthopaedic surgery, it also covers research, rehabilitation and physiotherapy. While of primary interest to the orthopaedic surgeon, rheumatologist, physiatrist and physiotherapist, this book will also be relevant to the haematologist responsible for the care of the haemophiliac patient.




Textbook of Hemophilia


Book Description

The only up-to-date definitive reference source onhemophilia This book is an invaluable resource that provides an overview ofall aspects of the care of patients with haemophilia. Covering how to assess both bleeding children and adults,Haemophilia A and B, molecular basis of the disease, the role offactors in coagulation, epidemiology, pharmacokinetics, andtreatment of inhibitors. There will also be a section onmusculoskeletal aspects of haemophilia as well as newerdevelopments such as gene therapy and rare bleedingdisorders. Textbook of Hemophilia is ideal for: Trainees and residents in hematology Hematologists in practice Specialists working in thrombosis and hemostasis as well astransfusion medicine Why Buy This Book? The only up-to-date definitive reference source onhemophilia Essential for all those managing hemophilia patients Detailed guidance on assessment, diagnosis, management andtreatment Advice for everyday clinical questions Edited by three of the world’s leading experts onhemophilia




Advances in Hemophilia Treatment


Book Description

This book offers a comprehensive and state of the art overview of hemophilia management by reviewing all most recent advances and cutting edge information in this fast evolving field. As hemophilia patients are often affected by joint problems it also provides clear guidance on the surgical treatment of musculo-skeletal manifestations. The first part is devoted to the disease’s pathophysiology (differentiating hemophilia A and B), genetics, pharmacotherapy – including replacement and non-replacement therapy – and gene therapy, as well as quality of life issues – also related to hemophilia carriers. The second part is then focused on joint problems, ranging from joint health assessment and pain control to surgical treatment of acute hemarthrosis and hemophilic arthropathy, i.e. radiosynovectomy, total joint arthroplasty and arthroscopic joint debridement. Written by experts drawn from leading institutions involved in treatment of hemophilia and related joint problems, this book offers a valuable resource to hematologists, orthopedic surgeons, rehabilitation physicians, radiologists, and pharmacy researchers.




Radiology of Haemophilic Arthropathies


Book Description

The use of potent coagulation factor concentrates has dramatically changed the clinical picture and the life expectancy of haemophiliacs. The aim of well-organized care of haemophiliacs is to prevent not only life-threatening bleeding episodes, but also the development of disabling arthropathies. In spite of numerous effective drugs and the beneficial effect of early synovectomy, haemophilic arthropathy will long remain a crux of everyday practice. Based on 10 years' experience at the National Institute of Haematology and Blood Transfusion, this volume presents a detailed description of the X-ray morphology of haemophilic arthropathy. The rich series of illustrations should serve for guidance in diagnostics and differential diagnostics, and will provide help in establishing the stage and in estimating the prognosis. It will be of interest to all physicians engaged in the care of haemophiliacs. Susan R. Hollan, M. D. Corresponding Member of the Hungarian Academy of Sciences, Professor of Haematology. Director of the National Institute of Haematology and Blood Transfusion 9 Acknowledgements I gratefully acknowledge the help of all those who have contributed to this mono graph. First I wish to acknowledge the help of Professor Susan Hollan, Corre sponding Member of the Hungarian Academy of Sciences, Director of the National Institute of Haematology and Blood Transfusion, Professor of Haematology at the Postgraduate Medical School, Editor-in-chief of Haemat%gia, an internation al quarterly, who provided us with the most modern equipment and has been interested in, and encouraged, our work throughout.




Congenital Bleeding Disorders


Book Description

This book describes in detail the clinical presentation, diagnosis, and management of a wide range of congenital bleeding disorders. It will assist readers in overcoming the significant challenges involved in clinical and laboratory diagnosis and in providing effective clinical care that makes optimal use of new products, including recombinant factor concentrate. The coverage ranges from hemophilia A and B and von Willebrand disease to rare bleeding disorders such as congenital factor V, factor X, factor XI, and factor XIII deficiency and inherited platelet function disorders. The exceptional attention to rarer conditions is of particular importance given the considerable risk of overlooking them during diagnosis, with potential consequences for disease-related morbidity and mortality. The authors are acknowledged specialists in the field from across the world who have particular expertise in the disorder that they discuss. The book will be of value to hematologists, oncologists, pediatricians, laboratory specialists and technicians, general physicians, and trainees.