The Meiotic Mechanisme
Author : Bernard John
Publisher :
Page : 32 pages
File Size : 29,67 MB
Release : 1973
Category :
ISBN :
The Meiotic Mechanism
Author : Bernard John
Publisher :
Page : 32 pages
File Size : 24,17 MB
Release : 1973
Category : Meiosis
ISBN :
Book Description
Meiosis
Author : Bernard John
Publisher : Cambridge University Press
Page : 411 pages
File Size : 32,68 MB
Release : 1990-04-12
Category : Science
ISBN : 0521350530
Book Description
Meiosis, the antithesis of fertilization, is the unique genetically programmed mode of nuclear division associated with a halving of the chromosome number in sexually reproducing eukaryotes. It thus represents a key cellular and developmental pathway in the life of an organism. In this book, Bernard John presents the first complete, and the most authoritative, review of the events and mechanisms of meiosis including their scheduling, their mechanics and their biochemistry as well as their genetic control and the variations to be found in them in both sexual and subsexual systems. The text is superbly illustrated with 131 figures and 73 tables. Meiosis must be regarded as essential reading for all students, teachers and research workers with an interest in eukaryotic cell biology and genetics.
Meiosis in Development and Disease
Author :
Publisher : Elsevier
Page : 390 pages
File Size : 33,2 MB
Release : 2023-01-16
Category : Science
ISBN : 0128201622
Book Description
Meiosis in Development and Disease, Volume 151 in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as The initiation stages of meiosis, The molecular basis and dynamics of meiotic cohesions, and their significance in human infertility, Chromatin, recombination, and the centromeres, Sites and structures that mediate segregation when crossing over calls out sick/Life (or at Least Meiosis) Without Crossing Over, Crossover maturation inefficiency, Non coding RNA mediated gene regulation in meiosis, Short chromosomes in meiotic recombination, Chromatin level changes during meiosis initiation vs. oncogenesis, and much more. Other sections of note include Chromosomal speciation revisited: Meiotic recombination and synapsis of evolutionary diverged homologs, Recombination suppression at specific chromosome regions, Unwinding during stressful times - mechanisms of helicases in meiotic recombination, Meiotic functions of PCH-2/TRIP13 and HORMADs, Crossover interference, Checkpoint control in meiotic prophase: Idiosyncratic demands require unique characteristics, The breadth of meiotic drive genes and mechanisms across the tree of life, and many more interesting topics. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Current Topics in Developmental Biology series - Updated release includes the latest information on the Meiosis in Development and Disease
Recombination and Meiosis
Author : Richard Egel
Publisher : Springer Science & Business Media
Page : 406 pages
File Size : 11,13 MB
Release : 2008-07-25
Category : Science
ISBN : 3540689842
Book Description
Once per life cycle, mitotic nuclear divisions are replaced by meiosis I and II – reducing chromosome number from the diploid level to a haploid genome and recombining chromosome arms by crossing-over. In animals, all this happens during formation of eggs and sperm – in yeasts before spore formation. The mechanisms of reciprocal exchange at crossover/chiasma sites are central to mainstream meiosis. To initiate the meiotic exchange of DNA, surgical cuts are made as a form of calculated damage that subsequently is repaired by homologous recombination. These key events are accompanied by ancillary provisions at the level of chromatin organization, sister chromatid cohesion and differential centromere connectivity. Great progress has been made in recent years in our understanding of these mechanisms. Questions still open primarily concern the placement of and mutual coordination between neighboring crossover events. Of overlapping significance, this book features two comprehensive treatises of enzymes involved in meiotic recombination, as well as the historical conceptualization of meiotic phenomena from genetical experiments. More specifically, these mechanisms are addressed in yeasts as unicellular model eukaryotes. Furthermore, evolutionary subjects related to meiosis are treated.
Recombination and Meiosis
Author : Richard Egel
Publisher : Springer Science & Business Media
Page : 375 pages
File Size : 34,24 MB
Release : 2007-11-13
Category : Science
ISBN : 3540753737
Book Description
This fascinating volume addresses the processes and mechanisms taking place in the cell during meiosis and recombination. It covers multicellular eukaryotes such as Drosophila, Arabidopsis, mice and humans. Once per life cycle, mitotic nuclear divisions are replaced by meiosis I and II – reducing chromosome number from the diploid level to a haploid genome, reshuffling the homologous chromosomes by their centromeres, and recombining chromosome arms by crossing-over.
Oxford Biology Readers: John, B. and Lewis, K.R. The meiotic mechanism
Author : John Juan Head
Publisher :
Page : 36 pages
File Size : 19,53 MB
Release : 1973
Category : Biology
ISBN :
Book Description
Meiosis and Gametogenesis
Author :
Publisher : Academic Press
Page : 447 pages
File Size : 31,43 MB
Release : 1997-11-24
Category : Science
ISBN : 0080584608
Book Description
In spite of the fact that the process of meiosis is fundamental to inheritance, surprisingly little is understood about how it actually occurs. There has recently been a flurry of research activity in this area and this volume summarizes the advances coming from this work. All authors are recognized and respected research scientists at the forefront of research in meiosis. Of particular interest is the emphasis in this volume on meiosis in the context of gametogenesis in higher eukaryotic organisms, backed up by chapters on meiotic mechanisms in other model organisms. The focus is on modern molecular and cytological techniques and how these have elucidated fundamental mechanisms of meiosis. Authors provide easy access to the literature for those who want to pursue topics in greater depth, but reviews are comprehensive so that this book may become a standard reference.Key Features* Comprehensive reviews that, taken together, provide up-to-date coverage of a rapidly moving field* Features new and unpublished information* Integrates research in diverse organisms to present an overview of common threads in mechanisms of meiosis* Includes thoughtful consideration of areas for future investigation
Characterizing Meiotic Mechanisms in C. Elegans
Author : Roshni Kasad
Publisher :
Page : 154 pages
File Size : 25,8 MB
Release : 2010
Category :
ISBN :
Book Description
Meiosis is the specialized cell division by which haploid egg and sperm cells are generated from mitotically dividing diploid germ cells. During early prophase, the environment of the nucleus is dynamic, as a given chromosome will undergo a series of encounters with homologous and nonhomologous chromosomes. A fundamental problem is how each chromosome is able to discriminate and accurately pair and form stabilized interactions via the synaptonemal complex only with its appropriate partner. It is only within this context of homologous interactions that recombination can take place, which is what allows for genetic diversity among sexually reproducing species. In Chapters 1 and 2, I will focus on homolog pairing and synapsis and will discuss experiments that point towards the Pairing Center protein HIM-8 functioning as a molecular link that couples these two events. In Chapter 3, I will discuss the role of the chromatin factor GAK-1 in meiosis. I will show that GAK-1 plays a role at multiple steps in meiosis, including recombination and maintenance of the synaptonemal complex. The data suggest that GAK-1 may function as a transcription factor for meiosis-specific genes, which would explain the pleiotropic effects seen in meiosis. These studies will hopefully further our understanding of the molecular basis of aneuploidies.
The Examination of Mechanisms Underlying Meiotic Chromosome Segregation
Author : Gloria Ann Brar
Publisher :
Page : 552 pages
File Size : 23,13 MB
Release : 2008
Category :
ISBN :
Book Description
Meiosis is the cell division by which gametes are produced. Meiotic chromosome segregation differs from Mitotic segregation in that one DNA replication phase is followed by two chromosome segregation phases. This allows generation of haploid products from a diploid precursor cell and depends on a number of cellular specializations that allow completion of a reductional segregation phase, in which homologous chromosomes segregate apart. I have investigated several mechanisms that contribute to meiotic segregation, including stepwise loss of meiotic cohesion, proper prophase progression and homolog pairing. I have found that stepwise cohesion loss is regulated by multiple mechanisms, including bulk phosphorylation of the meiotic cohesin Rec8. I also find that homolog linkage resulting from recombination regulates stepwise cohesion loss. Additionally, I present data that Rec8 plays an additional cellular role that is separable from its function as a cohesin. Rec8 is important for assembly of the Synaptonemal Complex (SC) and meiotic prophase progression. Like Rec8's cohesin role, this prophase role appears to be influenced by Rec8 phosphorylation. Finally, I present a basic characterization of the process of homolog pairing in early meiosis. I find that pairing is independent of DNA replication, but depends on cohesins, actin filaments, SC components and DSBs.
