Health Risks from Exposure to Low Levels of Ionizing Radiation


Book Description

This book is the seventh in a series of titles from the National Research Council that addresses the effects of exposure to low dose LET (Linear Energy Transfer) ionizing radiation and human health. Updating information previously presented in the 1990 publication, Health Effects of Exposure to Low Levels of Ionizing Radiation: BEIR V, this book draws upon new data in both epidemiologic and experimental research. Ionizing radiation arises from both natural and man-made sources and at very high doses can produce damaging effects in human tissue that can be evident within days after exposure. However, it is the low-dose exposures that are the focus of this book. So-called “late” effects, such as cancer, are produced many years after the initial exposure. This book is among the first of its kind to include detailed risk estimates for cancer incidence in addition to cancer mortality. BEIR VII offers a full review of the available biological, biophysical, and epidemiological literature since the last BEIR report on the subject and develops the most up-to-date and comprehensive risk estimates for cancer and other health effects from exposure to low-level ionizing radiation.




The Million Person Study of Low-Dose Radiation Health Effects


Book Description

This book presents original research findings of The Million Person Study of Low-Dose Radiation Health Effects (MPS), the largest and most comprehensive epidemiologic study of its kind to investigate the health effects of low-level chronic radiation exposure on American workers and veterans throughout the 20th century. Since the early 1900s, epidemiologists have studied the consequences of radiation exposures, yet the health effects of low levels received gradually over time remain unresolved. This uncertainty comes at a time when the public and workers are experiencing ever-increasing levels of radiation exposure from advances in medical radiation imaging techniques (e.g., CT scans), frequent flying at high altitudes, and environmental and occupational exposures. The MPS is providing answers by studying 30 radiation-exposed U.S. populations, including workers at nuclear power plants, radiologists, workers at former Manhattan Project sites, nuclear submariners, nuclear weapons test participants (atomic veterans), industrial radiographers, and radium dial painters. Ongoing for more than 20 years and coordinated by the National Council on Radiation Protection and Measurements, Vanderbilt University Medical Center and Memorial Sloan Kettering Cancer Center, the MPS is a national effort supported by the Department of Energy, National Aeronautics and Space Administration, U.S. Navy, Defense Threat Reduction Agency, Nuclear Regulatory Commission, Centers for Disease Control and Prevention, and the Environmental Protection Agency. Unparalleled in scope and quality, the MPS provides an understanding of low-dose health effects that is desperately needed for decision-makers and the radiation protection community as society continues to increase the uses of radiation technologies. Individual chapters were originally published in the International Journal of Radiation Biology.




Health Effects of Exposure to Low Levels of Ionizing Radiation


Book Description

This book reevaluates the health risks of ionizing radiation in light of data that have become available since the 1980 report on this subject was published. The data include new, much more reliable dose estimates for the A-bomb survivors, the results of an additional 14 years of follow-up of the survivors for cancer mortality, recent results of follow-up studies of persons irradiated for medical purposes, and results of relevant experiments with laboratory animals and cultured cells. It analyzes the data in terms of risk estimates for specific organs in relation to dose and time after exposure, and compares radiation effects between Japanese and Western populations.







The Future of Low Dose Radiation Research in the United States


Book Description

Exposures at low doses of radiation, generally taken to mean doses below 100 millisieverts, are of primary interest for setting standards for protecting individuals against the adverse effects of ionizing radiation. However, there are considerable uncertainties associated with current best estimates of risks and gaps in knowledge on critical scientific issues that relate to low dose radiation. The Nuclear and Radiation Studies Board of the National Academies hosted the symposium on The Future of Low Dose Radiation Research in the United States on May 8 and 9, 2019. The goal of the symposium was to provide an open forum for a national discussion on the need for a long-term strategy to guide a low dose radiation research program in the United States. The symposium featured presentations on low dose radiation programs around the world, panel discussions with representatives from governmental and nongovernmental organizations about the need for a low dose radiation research program, reviews of low dose radiation research in epidemiology and radiation biology including new directions, and lessons to be learned from setting up large research programs in non-radiation research fields. This publication summarizes the presentation and discussion of the symposium.




Analysis of Cancer Risks in Populations Near Nuclear Facilities


Book Description

In the late 1980s, the National Cancer Institute initiated an investigation of cancer risks in populations near 52 commercial nuclear power plants and 10 Department of Energy nuclear facilities (including research and nuclear weapons production facilities and one reprocessing plant) in the United States. The results of the NCI investigation were used a primary resource for communicating with the public about the cancer risks near the nuclear facilities. However, this study is now over 20 years old. The U.S. Nuclear Regulatory Commission requested that the National Academy of Sciences provide an updated assessment of cancer risks in populations near USNRC-licensed nuclear facilities that utilize or process uranium for the production of electricity. Analysis of Cancer Risks in Populations near Nuclear Facilities: Phase 1 focuses on identifying scientifically sound approaches for carrying out an assessment of cancer risks associated with living near a nuclear facility, judgments about the strengths and weaknesses of various statistical power, ability to assess potential confounding factors, possible biases, and required effort. The results from this Phase 1 study will be used to inform the design of cancer risk assessment, which will be carried out in Phase 2. This report is beneficial for the general public, communities near nuclear facilities, stakeholders, healthcare providers, policy makers, state and local officials, community leaders, and the media.







Health Risks of Radon and Other Internally Deposited Alpha-Emitters


Book Description

This book describes hazards from radon progeny and other alpha-emitters that humans may inhale or ingest from their environment. In their analysis, the authors summarize in one document clinical and epidemiological evidence, the results of animal studies, research on alpha-particle damage at the cellular level, metabolic pathways for internal alpha-emitters, dosimetry and microdosimetry of radionuclides deposited in specific tissues, and the chemical toxicity of some low-specific-activity alpha-emitters. Techniques for estimating the risks to humans posed by radon and other internally deposited alpha-emitters are offered, along with a discussion of formulas, models, methods, and the level of uncertainty inherent in the risk estimates.




NCRP Report


Book Description




Adverse Reproductive Outcomes in Families of Atomic Veterans


Book Description

Over the past several decades, public concern over exposure to ionizing radiation has increased. This concern has manifested itself in different ways depending on the perception of risk to different individuals and different groups and the circumstances of their exposure. One such group are those U.S. servicemen (the "Atomic Veterans" who participated in the atmospheric testing of nuclear weapons at the Nevada Test Site or in the Pacific Proving Grounds, who served with occupation forces in or near Hiroshima and Nagasaki, or who were prisoners of war in or near those cities at the time of, or shortly after, the atomic bombings. This book addresses the feasibility of conducting an epidemiologic study to determine if there is an increased risk of adverse reproductive outcomes in the spouses, children, and grandchildren of the Atomic Veterans.