Book Description
This national bestseller, now in paperback, reveals how all humans are descended from seven prehistoric women--the Seven Daughters of Eve.
Author : Bryan Sykes
Publisher : W. W. Norton & Company
Page : 324 pages
File Size : 15,84 MB
Release : 2002-05-17
Category : Science
ISBN : 9780393323146
This national bestseller, now in paperback, reveals how all humans are descended from seven prehistoric women--the Seven Daughters of Eve.
Author : D. Balasubramanian
Publisher : Universities Press
Page : 204 pages
File Size : 50,93 MB
Release : 2001
Category : Biology
ISBN : 9788173713828
Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
Page : 201 pages
File Size : 40,26 MB
Release : 2016-04-17
Category : Medical
ISBN : 0309388708
Mitochondrial replacement techniques (MRTs) are designed to prevent the transmission of mitochondrial DNA (mtDNA) diseases from mother to child. While MRTs, if effective, could satisfy a desire of women seeking to have a genetically related child without the risk of passing on mtDNA disease, the technique raises significant ethical and social issues. It would create offspring who have genetic material from two women, something never sanctioned in humans, and would create mitochondrial changes that could be heritable (in female offspring), and therefore passed on in perpetuity. The manipulation would be performed on eggs or embryos, would affect every cell of the resulting individual, and once carried out this genetic manipulation is not reversible. Mitochondrial Replacement Techniques considers the implications of manipulating mitochondrial content both in children born to women as a result of participating in these studies and in descendants of any female offspring. This study examines the ethical and social issues related to MRTs, outlines principles that would provide a framework and foundation for oversight of MRTs, and develops recommendations to inform the Food and Drug Administration's consideration of investigational new drug applications.
Author : Carl Zimmer
Publisher : Penguin
Page : 672 pages
File Size : 49,10 MB
Release : 2018-05-29
Category : Science
ISBN : 1101984600
2019 PEN/E.O. Wilson Literary Science Writing Award Finalist "Science book of the year"—The Guardian One of New York Times 100 Notable Books for 2018 One of Publishers Weekly's Top Ten Books of 2018 One of Kirkus's Best Books of 2018 One of Mental Floss's Best Books of 2018 One of Science Friday's Best Science Books of 2018 “Extraordinary”—New York Times Book Review "Magisterial"—The Atlantic "Engrossing"—Wired "Leading contender as the most outstanding nonfiction work of the year"—Minneapolis Star-Tribune Celebrated New York Times columnist and science writer Carl Zimmer presents a profoundly original perspective on what we pass along from generation to generation. Charles Darwin played a crucial part in turning heredity into a scientific question, and yet he failed spectacularly to answer it. The birth of genetics in the early 1900s seemed to do precisely that. Gradually, people translated their old notions about heredity into a language of genes. As the technology for studying genes became cheaper, millions of people ordered genetic tests to link themselves to missing parents, to distant ancestors, to ethnic identities... But, Zimmer writes, “Each of us carries an amalgam of fragments of DNA, stitched together from some of our many ancestors. Each piece has its own ancestry, traveling a different path back through human history. A particular fragment may sometimes be cause for worry, but most of our DNA influences who we are—our appearance, our height, our penchants—in inconceivably subtle ways.” Heredity isn’t just about genes that pass from parent to child. Heredity continues within our own bodies, as a single cell gives rise to trillions of cells that make up our bodies. We say we inherit genes from our ancestors—using a word that once referred to kingdoms and estates—but we inherit other things that matter as much or more to our lives, from microbes to technologies we use to make life more comfortable. We need a new definition of what heredity is and, through Carl Zimmer’s lucid exposition and storytelling, this resounding tour de force delivers it. Weaving historical and current scientific research, his own experience with his two daughters, and the kind of original reporting expected of one of the world’s best science journalists, Zimmer ultimately unpacks urgent bioethical quandaries arising from new biomedical technologies, but also long-standing presumptions about who we really are and what we can pass on to future generations.
Author : Jean-Pierre Changeux
Publisher : Oxford University Press, USA
Page : 344 pages
File Size : 46,93 MB
Release : 1995
Category : Medical
ISBN :
Throughout history, humans have been fascinated by their origins. The evolutionary development of the human brain has been of particular interest since our intellectual, emotional, and cultural capacities are considered to be unique among animals. This book brings together a group of eminent scientists from the fields of evolutionary biology, anthropology, neuroscience, and psychology. Their views provide a starting point for a debate based on the most recent scientific data relating to the evolutionary origins of the human brain, drawing together knowledge from sciences of the past (paleontology, archaeology) and those of the present and future (molecular neurobiology, population genetics). The result is a lively, informative, and valuable synthesis that will interest a wide range of students and researchers in these fields.
Author : Stephen Oppenheimer
Publisher : Robinson
Page : 263 pages
File Size : 44,24 MB
Release : 2012-03-01
Category : Social Science
ISBN : 1780337531
In a brilliant synthesis of genetic, archaeological, linguistic and climatic data, Oppenheimer challenges current thinking with his claim that there was only one successful migration out of Africa. In 1988 Newsweek headlined the startling discovery that everyone alive on the earth today can trace their maternal DNA back to one woman who lived in Africa 150,000 years ago. It was thought that modern humans populated the world through a series of migratory waves from their African homeland. Now an even more radical view has emerged, that the members of just one group are the ancestors of all non-Africans now alive, and that this group crossed the mouth of the Red Sea a mere 85,000 years ago. It means that not only is every person on the planet descended from one African 'Eve' but every non-African is related to a more recent Eve, from that original migratory group. This is a revolutionary new theory about our origins that is both scholarly and entertaining, a remarkable account of the kinship of all humans. Further details of the findings in this book are presented at www.bradshawfoundation.com/stephenoppenheimer/
Author : National Research Council
Publisher : National Academies Press
Page : 128 pages
File Size : 33,54 MB
Release : 1988-01-01
Category : Science
ISBN : 0309038405
There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.
Author : The Royal Society
Publisher : National Academies Press
Page : 239 pages
File Size : 32,80 MB
Release : 2021-01-16
Category : Medical
ISBN : 0309671132
Heritable human genome editing - making changes to the genetic material of eggs, sperm, or any cells that lead to their development, including the cells of early embryos, and establishing a pregnancy - raises not only scientific and medical considerations but also a host of ethical, moral, and societal issues. Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably and without introducing undesired changes - criteria that have not yet been met, says Heritable Human Genome Editing. From an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, and the U.K.'s Royal Society, the report considers potential benefits, harms, and uncertainties associated with genome editing technologies and defines a translational pathway from rigorous preclinical research to initial clinical uses, should a country decide to permit such uses. The report specifies stringent preclinical and clinical requirements for establishing safety and efficacy, and for undertaking long-term monitoring of outcomes. Extensive national and international dialogue is needed before any country decides whether to permit clinical use of this technology, according to the report, which identifies essential elements of national and international scientific governance and oversight.
Author : David Reich
Publisher : Oxford University Press
Page : 400 pages
File Size : 27,7 MB
Release : 2018-03-29
Category : Science
ISBN : 0192554387
The past few years have seen a revolution in our ability to map whole genome DNA from ancient humans. With the ancient DNA revolution, combined with rapid genome mapping of present human populations, has come remarkable insights into our past. This important new data has clarified and added to our knowledge from archaeology and anthropology, helped resolve long-existing controversies, challenged long-held views, and thrown up some remarkable surprises. The emerging picture is one of many waves of ancient human migrations, so that all populations existing today are mixes of ancient ones, as well as in many cases carrying a genetic component from Neanderthals, and, in some populations, Denisovans. David Reich, whose team has been at the forefront of these discoveries, explains what the genetics is telling us about ourselves and our complex and often surprising ancestry. Gone are old ideas of any kind of racial 'purity', or even deep and ancient divides between peoples. Instead, we are finding a rich variety of mixtures. Reich describes the cutting-edge findings from the past few years, and also considers the sensitivities involved in tracing ancestry, with science sometimes jostling with politics and tradition. He brings an important wider message: that we should celebrate our rich diversity, and recognize that every one of us is the result of a long history of migration and intermixing of ancient peoples, which we carry as ghosts in our DNA. What will we discover next?
Author :
Publisher :
Page : 0 pages
File Size : 22,45 MB
Release : 2002
Category : Cells
ISBN : 9780815332183