The Pancreas Revisited, An Issue of Surgical Clinics


Book Description

This issue of Surgical Clinics of North America focuses on The Pancreas Revisited, and is edited by Dr. Avram Cooperman. Articles will include: Is preclinical diagnosis / or prevention of cancer of the pancreas be possible?; Preoperative evaluation of a pancreas mass: diagnostic options; Clinical evaluation of a pancreatic mass: what is essential and practical from a therapeutic standpoint?; Screening of patients at risk for familial pancreatic cancer— what is bene?cial?; Incidental IPMN, cystic /premalignant lesions of the pancreas: the case for selective, conservative management; Preoperative stenting for benign and malignant periampullary cancer: the case for selective application; Preoperative stenting for benign and malignant periampullary diseases: unnecessary if not harmful?; Timing of pancreatic resection and patient outcomes: is there a difference?; Outcome analysis for pancreatic surgery: actual vs actuarial methods?; The role of radiation in pancreatic cancer: the European and American view; Adjuvant or neoadjuvant therapy in the treatment in pancreatic malignancies: Where are we?; Nonoperative Ablation of Pancreatic Neoplasms; Incidental IPMN, cystic/ premalignant lesions of the pancreas: The case for aggressive management; Ex Vivo surgery for low grade tumors involving celiac and superior mesenteric arteries; and more!




The Exocrine Pancreas


Book Description

The secretions of the exocrine pancreas provide for digestion of a meal into components that are then available for processing and absorption by the intestinal epithelium. Without the exocrine pancreas, malabsorption and malnutrition result. This chapter describes the cellular participants responsible for the secretion of digestive enzymes and fluid that in combination provide a pancreatic secretion that accomplishes the digestive functions of the gland. Key cellular participants, the acinar cell and the duct cell, are responsible for digestive enzyme and fluid secretion, respectively, of the exocrine pancreas. This chapter describes the neurohumoral pathways that mediate the pancreatic response to a meal as well as details of the cellular mechanisms that are necessary for the organ responses, including protein synthesis and transport and ion transports, and the regulation of these responses by intracellular signaling systems. Examples of pancreatic diseases resulting from dysfunction in cellular mechanisms provide emphasis of the importance of the normal physiologic mechanisms.




Staging Laparoscopy


Book Description

Included here is a discussion of the pathophysiological aspects and risks of laparoscopic staging (such as trocar metastases) on the basis of international experience.




Polycystic Ovary Syndrome


Book Description

This volume includes the latest diagnostic criteria for PCOS and comprises the most up-to-date information about the genetic features and pathogenesis of PCOS. It critically reviews the methodological approaches and the evidence for various PCOS susceptibility genes. The book also discusses additional familial phenotypes of PCOS and their potential genetic basis. All four editors of this title are extremely prominent in the field of PCOS.




The Pancreas


Book Description

This brand new updated edition of the most comprehensive reference book on pancreatic disease details the very latest knowledge on genetics and molecular biological background in terms of anatomy, physiology, pathology, and pathophysiology for all known disorders. Included for the first time, are two brand new sections on the key areas of Autoimmune Pancreatitis and Benign Cystic Neoplasms. In addition, this edition is filled with over 500 high-quality illustrations, line drawings, and radiographs that provide a step-by-step approach to all endoscopic techniques and surgical procedures. Each of these images can be downloaded via an online image bank for use in scientific presentations. Every existing chapter in The Pancreas: An Integrated Textbook of Basic Science, Medicine and Surgery, 3rd Edition has been thoroughly revised and updated to include the many changes in clinical practice since publication of the current edition. The book includes new guidelines for non-surgical and surgical treatment; new molecular biologic pathways to support clinical decision making in targeted treatment of pancreatic cancer; new minimally invasive surgical approaches for pancreatic diseases; and the latest knowledge of neuroendocrine tumors and periampullary tumors. The most encyclopedic book on the pancreas—providing outstanding and clear guidance for the practicing clinician Covers every known pancreatic disorder in detail including its anatomy, physiology, pathology, pathophysiology, diagnosis, and management Completely updated with brand new chapters Over 500 downloadable illustrations An editor and author team of high international repute who present global best-practice The Pancreas: An Integrated Textbook of Basic Science, Medicine and Surgery, 3rd Edition is an important book for gastroenterologists and gastrointestinal surgeons worldwide.




Clinical Pancreatology for Practising Gastroenterologists and Surgeons


Book Description

Clinical Pancreatology Since the book Clinical Pancreatology for Practising Gastroenterologists and Surgeons was first published sixteen years ago, the knowledge and clinical management of pancreatic diseases have developed markedly. Thanks to the development of the translational research and the from bench to bedside concept, much progress from the lab has been applied to clinical practice. In addition, several highly relevant clinical trials published over the last years have resulted in the update and optimisation of clinical guidelines. A new and validated classification of severity and complications of acute pancreatitis is firmly rooted in clinical practice and has been the basis for the development of minimally invasive approaches to pancreatic necrosis. The etiopathogenic knowledge of chronic pancreatitis and other pancreatopaties, like that associated with diabetes mellitus, has developed significantly. Especially important has been the development of the field of cystic pancreatic tumours, which has been reflected in the publication of several guidelines and consensus reports over the last few years. Most research efforts have focused on pancreatic cancer, which have led and will further lead to a significant increase in the therapeutic armamentarium against this devastating disease. Finally, many newly published studies have changed the concept, causes, clinical relevance, diagnosis and treatment of exocrine pancreatic insufficiency. This new edition of Clinical Pancreatology for Practising Gastroenterologists and Surgeons has enjoyed the collaboration of the world’s leading experts in each of the areas of clinical pancreatology with the aim of facilitating gastroenterologists, surgeons, oncologists, internists, nutritionists, diabetologists, paediatricians, radiologists, pathologists and other specialists in their decision making when facing patients with pancreatic diseases in their daily clinical practice. All in all, this book supplies an indispensable update of the relevant aspects of clinical pancreatology.




Polyphenols: Mechanisms of Action in Human Health and Disease


Book Description

Polyphenols: Mechanisms of Action in Human Health and Disease, Second Edition describes the mechanisms of polyphenol antioxidant activities and their use in disease prevention. Chapters highlight the anti-inflammatory activity of polyphenols on key dendritic cells, how they modulate and suppress inflammation, and how they are inactivated or activated by metabolism in the gut and circulating blood. Polyphenols have proven effective for key health benefits, including bone health, organ health, cardiac and vascular conditions, absorption and metabolism, and cancer and diseases of the immune system. They are a unique group of phytochemicals that are present in all fruits, vegetables and other plant products. This very diverse and multi-functional group of active plant compounds contain powerful antioxidant properties and exhibit remarkable chemical, biological and physiological properties, including cancer prevention and cardio-protective activities. - Expands coverage on green tea, cocoa, wine, cumin and herbs - Outlines their chemical properties, bioavailability and metabolomics - Provides a self-teaching guide to learn the mechanisms of action and health benefits of polyphenols




MR Imaging of the Pancreas, An Issue of Magnetic Resonance Imaging Clinics of North America


Book Description

This issue of MRI Clinics of North America focuses on MR Imaging of the Pancreas, and is edited by Drs. Kumar Sandrasegaran and Dushyant V. Sahani. Articles will include: Advanced MRI Techniques for Pancreas Imaging; PET/MRI for Pancreatic Diseases; The Role of MRI in Pancreas Cancer; Genetics of Pancreatic Neoplasms and Role of Screening; Cystic Pancreatic Tumors; Rare Pancreatic Tumors; Autoimmune Pancreatitis; Routine MRI for Pancreas; Neuroendocrine Tumors; Acute Pancreatitis: How Can MRI Help; Chronic Pancreatitis: What the Clinician Wants to Know from MRI; and more!




Silverberg's Principles and Practice of Surgical Pathology and Cytopathology 4 Volume Set with Online Access


Book Description

Silverberg's Principles and Practice of Surgical Pathology and Cytopathology is one of the most durable reference texts in pathology. Thoroughly revised and updated, this state-of-the-art new edition encompasses the entire fields of surgical pathology and cytopathology in a single source. Its practice-oriented format uniquely integrates these disciplines to present all the relevant features of a particular lesion, side by side. Over 4000 color images depict clinical features, morphological attributes, histochemical and immunohistochemical findings, and molecular characteristics of all lesions included. This edition features new highly experienced and academically accomplished editors, while chapters are written by the leading experts in the field (several new to this edition, bringing a fresh approach). Dr Steven Silverberg's practical approach to problem solving has been carefully preserved. The print book is packaged with access to a secure, electronic copy of the book, providing quick and easy access to its wealth of text and images.




ERCP E-Book


Book Description

Over the past 40 years, ERCP has become an effective therapeutic modality with diagnostic purposes that are continually improved.. The 3rd Edition of this practical reference helps you make the most of today's endoscopic retrograde cholangiopancreatography in your practice. You'll find authoritative, highly illustrated guidance on every aspect of ERCP, including coverage of the latest techniques. - Clearly depicts each step of ERCP procedures in dozens of step-by-step videos, including Needle Knife Sphincterotomy, Biliary Sphincterotomy, Cannulation, and Fistulotomy. - Provides clear guidelines on when and when not to perform ERCP. - Features superb, full-color images, and a wealth of illustrative diagrams. - Includes new chapters that cover duodenoscope reprocessing; endomicrocopy; EUS-guided endotherapy related to pancreatobiliary disorders; and CT and MRCP related to pancreatobiliary disorders. - Contains updated information on radiofrequency ablation for cancer, percutaneous vs. endoscopic drainage, scope cleaning practices, and pancreatic necrosis. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.