The Pathway for Oxygen


Book Description

It is rare indeed for one book to be both a first-rate classroom text and a major contribution to scholarship. The Pathway for Oxygen is such a book, offering a new approach to respiratory physiology and morphology that quantitatively links the two. Professionalism in science has led to a compartmentalization of biology. Function is the domain of the physiologist, structure that of the morphologist, and they often operate with vastly disparate concepts and procedures. Yet the performance of the respiratory system depends both on structural and on functional properties that cannot be separated. The first chapter of The Pathway for Oxygen engages the student with the design and function of the vertebrate respiratory organs from a comparative viewpoint. The second chapter adds to that foundation the link between cell energetics and oxygen needs of the whole animal. With Chapter 3 the excitement begins--new ideas, fresh attacks on old problems, and a fuller account of the power of the quantitative approach Dr. Weibel has pioneered. The Pathway for Oxygen will be read eagerly by medical students, graduate students, advanced undergraduates in zoology--and by their professors.




Regulation of Tissue Oxygenation, Second Edition


Book Description

This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.




How Tobacco Smoke Causes Disease


Book Description

This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.




Basic Physiology for Anaesthetists


Book Description

Easily understood, up-to-date and clinically relevant, this book provides junior anaesthetists with an essential physiology resource.




Anatomy and Physiology


Book Description




Lung Development


Book Description

Knowledge about the mechanisms of lung development has been growing rapidly, especially with regard to cellular and molecular aspects of growth and differentiation. This authoritative international volume reviews key aspects of lung development in health and disease by providing a comprehensive review of the complex series of cellular and molecular interactions required for lung development. It covers such topics as pulmonary hypoplasia, effects of malnutrition, and pulmaonary angiogenesis. An indispensable reference for all those involved in studying or treating lung disease in neonates and children, the book offers a unique view of the development of this essential organ.




Respiratory Care Anatomy and Physiology


Book Description

Perfect for both practicing therapists and students in respiratory therapy and associated professions, this well-organized text offers the most clinically relevant and up-to-date information on respiratory applied anatomy and physiology. Content spans the areas of basic anatomy and physiology of the pulmonary, cardiovascular, and renal systems, and details the physiological principles underlying common therapeutic, diagnostic, and monitoring therapies and procedures. Using a clear and easy-to-understand format, this text helps you take a more clinical perspective and learn to think more critically about the subject matter. Open-ended concept questions require reasoned responses based on thorough comprehension of the text, fostering critical thinking and discussion. Clinical Focus boxes throughout the text place key subject matter in a clinical context to connect theory with practice. Chapter outlines, chapter objectives, key terms, and a bulleted chapter summary highlight important concepts and make content more accessible. Appendixes contain helpful tables and definitions of terms and symbols. NEW! Chapter on the physiological basis for treating sleep-disordered breathing clarifies the physiological mechanisms of sleep-disordered breathing and the various techniques required to treat this type of disorder. NEW! Reorganization of content places the section on the renal system before the section on integrated responses in exercise and aging to create a more logical flow of content. NEW! More Clinical Focus scenarios and concept questions provide additional opportunities to build upon content previously learned and to apply new information in the text.




Concepts of Biology


Book Description

Black & white print. Concepts of Biology is designed for the typical introductory biology course for nonmajors, covering standard scope and sequence requirements. The text includes interesting applications and conveys the major themes of biology, with content that is meaningful and easy to understand. The book is designed to demonstrate biology concepts and to promote scientific literacy.




Biology for AP ® Courses


Book Description

Biology for AP® courses covers the scope and sequence requirements of a typical two-semester Advanced Placement® biology course. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology for AP® Courses was designed to meet and exceed the requirements of the College Board’s AP® Biology framework while allowing significant flexibility for instructors. Each section of the book includes an introduction based on the AP® curriculum and includes rich features that engage students in scientific practice and AP® test preparation; it also highlights careers and research opportunities in biological sciences.




Oxygen Sensing


Book Description

The ability of cells to sense and respond to changes in oxygenation underlies a multitude of developmental, physiological, and pathological processes. This volume provides a comprehensive compendium of experimental approaches to the study of oxygen sensing in 48 chapters that are written by leaders in their fields.