The Porphyrin Handbook


Book Description

The Porphyrin Handbook, Volume 12: The Iron and Cobalt Pigments: Biosynthesis, Structure, and Degradation provides information pertinent to every aspect of the chemistry, synthesis, spectroscopy, and structure of phthalocyanines. This book presents the biochemical and clinical aspects of genetically transmitted or drug-induced diseases associated with errors in heme metabolism. Organized into eight chapters, this volume begins with an overview of the comparison of regulatory principles in animal and plant tetrapyrrole biosynthesis. This text then examines the biology and medical implications of porphyrin systems. Other chapters consider the transformation of hemes into bile pigments, the organic synthesis of bilins, and the pathways of degradation of chlorophyll in senescent plants. This book discusses as well the biosynthesis of porphyrins, vitamin B12, and chlorophylls. The final chapter deals with genome sequencing projects that provide sources of genes encoding the enzymes needed for the synthesis of the intermediates. This book is a valuable resource for research scientists, engineers, and clinicians.




The Porphyrin Handbook, Volumes 11-20


Book Description

Announcing the sequel to the first ten volumes of The Porphyrin Handbook, which provided an authoritative treatise on the porphryin system and dealt in fine detail with the synthesis, chemistry, spectroscopy, and applications of porphyrins. The ten latest volumes 11-20 address those major disciplinary areas not covered in the first, including biology and medical implications of porphyrin systems, the biosynthesis of porphyrins, chlorophylls and vitamin B12. Other areas include the multitude of genetically transmitted and drug induced diseases associated with errors in heme metabolism, the transformations of hemes into bile pigments, the organic syntheses of bilins, very recent work on phytochrome, and the pathways of degradation of chlorophyll in senescent plants. In addition, volumes 11-20 address every aspect of synthesis, chemistry, structure and spectroscopy of phthalocyanines which will appeal to scientists in fields ranging from mathematics through physics, chemistry and biochemistry, to biology and medicine. . By the same Editors as the successful first Porphyrin Handbook, published in 2000. . Consists of 61 chapters written by internationally recognized experts. . Clear, concise, and uniform presentation with many hundreds of figures, tables and structural formulae. Including volume indices and cumulative index.




The Porphyrin Handbook


Book Description

The Porphyrin Handbook, Volume 11: Bioinorganic and Bioorganic Chemistry presents the fundamental aspects of the synthesis, structure, chemistry, and spectroscopy of phthalocyanines. This book discusses the biology and medical implications of porphyrin systems. Organized into seven chapters, this volume begins with an overview of the design, synthesis, and study of the structural and functional models of heme/copper terminal oxidases. This text then examines the proteins containing iron-protoporphyrin IX (heme), which play key roles in photosynthesis and respiration. Other chapters consider the syntheses of chiral porphyrin derivatives and summarize the uses of such compounds in enantioselective control. This book discusses as well the reactivity and synthesis of synthetic carbine metalloporphyrins. The final chapter deals with the B12-coenzymes, which is the most complex and physiologically important organometallic enzymatic reactions that directly depend on the reactivity of metal coordinated organic ligands. This book is a valuable resource for research scientists, clinicians, and engineers.