The Porphyrins V7


Book Description

The Porphyrins, Volume VII: Biochemistry, Part B is devoted to the biochemistry of porphyrins, their precursors, and related compounds. The book covers the structure and function of the major heme proteins and their reconstitution and metal substitution, along with proteins derived from green photosynthetic bacteria. This volume is organized into 11 chapters and begins with an introduction to the cytochrome oxidase, paying particular attention to its isolation and characterization as well as biosynthesis. The discussion then turns to the electron transfer functions of cytochromes b and c; the structure of cytochrome c; and the proposed structures for peroxidases, catalases, and chloroperoxidase. The following chapters explore the biochemical mechanism and control of the catalytic function of cytochrome P-450 and associated electron transport chains, metal substitution in hemoglobin and myoglobin, and reconstitution experiments on various hemoproteins with particular attention to the removal of heme and reassembly into a heme-protein complex, along with protein folding around the heme. This book will be of interest to inorganic, organic, physical, and biochemists involved in the study of the biochemistry of porphyrins.




Comparative Biochemistry V7


Book Description

Comparative Biochemistry: A Comprehensive Treatise, Volume VII: Supplementary Volume focuses on the processes, methodologies, and approaches involved in molecular biochemistry. The selection first offers information on expressions of the pentose phosphate cycle, including description, criteria for the presence of the pentose phosphate cycle, chordates, segmented worms, mollusks, echinoderms, roundworms, flatworms, algae, and higher plants. The text then ponders on chitin and mucosubstances, as well as the distribution and biochemistry of chitin, molecular structure and function of chitin, and chitin in relation to mucosubstances. The publication reviews the cellular aspects of active transport and hormones and behavior. Topics include relations between inorganic ions, sugar, amino acids, fatty acids, and bioelectric potentials; aspects of the regulation of the intracellular pool of free amino acids; hormones and permeability characteristics of living cellular membranes; and chemical nature of the structure responsible for the permeability characteristics of living membranes. The recording and measurement of behavior, role of hormones in the patterning of behavior, and hormones influencing behavior and the behavior most subject to hormonal influence and control are also discussed. The selection is a dependable source of data for readers interested in the processes, methodologies, approaches involved in biochemistry.




Biochemical Actions of Hormones V7


Book Description

Biochemical Actions of Hormones, Volume VII is a nine-chapter text that covers a broad range of subjects representing research efforts on hormone action. This book deals first with the developments on hormones of the thymus and the evidence on the regulation of liver steroid and drug metabolism by the hypothalamus and anterior pituitary. These topics are followed by discussions on the regulation by neurotransmitters in the hypothalamus of LHRH and somatostatin; the hormonal regulation of protein degradation in liver and in isolated cells; and the hormonal regulation of lipid mobilization from adipose tissue. Considerable chapters are devoted to steroid hormone mechanisms and the cell genetics of glucocorticoid responsiveness. The remaining chapters explore the mero-receptor and androgenic regulation in male accessory tissue. These chapters also highlight the molecular biological aspects of thyroid hormone action. This volume is an ideal source for biologists, biochemists, and researchers working in the subject and in related fields.




Report of Investigations


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Vibrational Spectroscopy in Protein Research


Book Description

Vibrational Spectroscopy in Protein Research offers a thorough discussion of vibrational spectroscopy in protein research, providing researchers with clear, practical guidance on methods employed, areas of application, and modes of analysis. With chapter contributions from international leaders in the field, the book addresses basic principles of vibrational spectroscopy in protein research, instrumentation and technologies available, sampling methods, quantitative analysis, origin of group frequencies, and qualitative interpretation. In addition to discussing vibrational spectroscopy for the analysis of purified proteins, chapter authors also examine its use in studying complex protein systems, including protein aggregates, fibrous proteins, membrane proteins and protein assemblies. Emphasis throughout the book is placed on applications in human tissue, cell development, and disease analysis, with chapters dedicated to studies of molecular changes that occur during disease progression, as well as identifying changes in tissues and cells in disease studies. - Provides thorough guidance in implementing cutting-edge vibrational spectroscopic methods from international leaders in the field - Emphasizes in vivo, in situ and non-invasive analysis of proteins in biomedical and life science research more broadly - Contains chapters that address vibrational spectroscopy for the study of simple purified proteins and protein aggregates, fibrous proteins, membrane proteins and protein assemblies




Handbook Of Porphyrin Science: With Applications To Chemistry, Physics, Materials Science, Engineering, Biology And Medicine (Volumes 41-44)


Book Description

Porphyrins, phthalocyanines and their numerous analogs and derivatives are materials of tremendous importance in chemistry, materials science, physics, biology and medicine. They comprise the red color in blood (heme) and the green in leaves (chlorophyll); they are also excellent ligands that can coordinate with almost every metal in the Periodic Table. Grounded in natural systems, porphyrins are incredibly versatile and can be modified in many ways; each new modification yields derivatives demonstrating new chemistry, physics and biology, with a vast array of medicinal and technical applications.Because porphyrins are currently employed as platforms for study of theoretical principles and applications in a wide variety of fields, the Handbook of Porphyrin Science represents a timely ongoing series dealing in detail with the synthesis, chemistry, physicochemical and medical properties and applications of polypyrrole macrocycles. It is noteworthy that every year, new applications for tetrapyrrole ligands are developed and exploited.Professors Karl Kadish, Kevin Smith and Roger Guilard are internationally recognized experts in the research field of porphyrinoids, each having his own separate but complementary area of expertise in the field. Between them, they have published over 1750 peer-reviewed papers and jointly edited more than 55 books on diverse topics related to porphyrins and phthalocyanines. In assembling the set of new volumes of this unique handbook, they have selected and attracted the very best scientists in each sub-discipline as contributing authors.The Handbook of Porphyrin Science will prove to be a modern authoritative treatise on the subject as it continues as a collection of up-to-date works by world-renowned experts in the field. Complete with hundreds of figures, tables and structural formulas, and thousands of literature citations, all researchers and graduate students in this field will find it to be an essential, major reference source now, and for many years to come.




The Porphyrin Handbook, Volume 2


Book Description

Scientists in such fields as mathematics, physics, chemistry, biochemistry, biology, and medicine are currently involved in investigations of porphyrins and their numerous analogues and derivatives. Porphyrins are being used as platforms for the study of theoretical principles, as catalysts, as drugs, as electronic devices, and as spectroscopic probes in biology and medicine. The need for an up-to-date and authoritative treatise on the porphyrin system has met with universal acclaim amongst scientists and investigators.







Journal


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The Porphyrins


Book Description