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The Organic Chemistry of Drug Design and Drug Action

Author : Richard B. Silverman

Publisher : Elsevier

Page : 650 pages

File Size : 18,66 MB

Release : 2012-12-02

Category : Science

ISBN : 0080513379

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Book Description

Standard medicinal chemistry courses and texts are organized by classes of drugs with an emphasis on descriptions of their biological and pharmacological effects. This book represents a new approach based on physical organic chemical principles and reaction mechanisms that allow the reader to extrapolate to many related classes of drug molecules. The Second Edition reflects the significant changes in the drug industry over the past decade, and includes chapter problems and other elements that make the book more useful for course instruction. - New edition includes new chapter problems and exercises to help students learn, plus extensive references and illustrations - Clearly presents an organic chemist's perspective of how drugs are designed and function, incorporating the extensive changes in the drug industry over the past ten years - Well-respected author has published over 200 articles, earned 21 patents, and invented a drug that is under consideration for commercialization



Introduction to Basics of Pharmacology and Toxicology

Author : Gerard Marshall Raj

Publisher : Springer Nature

Page : 410 pages

File Size : 19,77 MB

Release : 2019-11-16

Category : Medical

ISBN : 9813297794

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Book Description

This book illustrates, in a comprehensive manner, the most crucial principles involved in pharmacology and allied sciences. The title begins by discussing the historical aspects of drug discovery, with up to date knowledge on Nobel Laureates in pharmacology and their significant discoveries. It then examines the general pharmacological principles - pharmacokinetics and pharmacodynamics, with in-depth information on drug transporters and interactions. In the remaining chapters, the book covers a definitive collection of topics containing essential information on the basic principles of pharmacology and how they are employed for the treatment of diseases. Readers will learn about special topics in pharmacology that are hard to find elsewhere, including issues related to environmental toxicology and the latest information on drug poisoning and treatment, analytical toxicology, toxicovigilance, and the use of molecular biology techniques in pharmacology. The book offers a valuable resource for researchers in the fields of pharmacology and toxicology, as well as students pursuing a degree in or with an interest in pharmacology.



Oral Drug Absorption

Author : Jennifer B. Dressman

Publisher : CRC Press

Page : 432 pages

File Size : 16,42 MB

Release : 2016-04-19

Category : Medical

ISBN : 1420077341

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Book Description

Oral Drug Absorption, Second Edition thoroughly examines the special equipment and methods used to test whether drugs are released adequately when administered orally. The contributors discuss methods for accurately establishing and validating in vitro/in vivo correlations for both MR and IR formulations, as well as alternative approaches for MR an



Drug Metabolism in Diseases

Author : Wen Xie

Publisher : Academic Press

Page : 296 pages

File Size : 32,76 MB

Release : 2016-09-12

Category : Medical

ISBN : 0128029633

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Book Description

Drug Metabolism in Diseases is a comprehensive reference devoted to the current state of research on the impact of various disease states on drug metabolism. The book contains valuable insights into mechanistic effects and examples of how to accurately predict drug metabolism during these different pathophysiological states. Each chapter clearly presents the effects of changes in drug metabolism and drug transporters on pharmacokinetics and disposition. This is a unique and useful approach for all those involved in drug discovery and development, and for clinicians and researchers in drug metabolism, pharmacology, and clinical pharmacology. - Written and edited by leaders in drug metabolism from academia and industry - Covers important topics, such as pharmacogenomics, drug metabolism in transplant patients, xenobiotic receptors, drug metabolism in geriatric and pediatric populations, and more - Highlights topics of importance in drug discovery and development, and for safe and effective drug use in the clinic



Delmar Nurse's Drug Handbook 2010 Edition (Book Only)

Author : George R. Spratto

Publisher : Cengage Learning

Page : 0 pages

File Size : 48,72 MB

Release : 2009-06

Category : Medical

ISBN : 9781111319328

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Book Description

Put the latest edition of today's most trusted drug reference guide in your hands with DELMAR NURSE'S DRUG HANDBOOK(TM) 2012 EDITION. This essential resource clearly describes the most important information for over 770 of the latest and most common FDA-approved drugs. Each entry provides a wealth of information concerning drug action, pharmacokinetics, dosage, interactions, and contraindications. Clear guidelines are also provided for administration of drugs, communication with clients, and nursing considerations. This edition offers even more convenience with an iPhone/iPod touch Application that places the complete drug guide at your fingertips with enhanced search options.



Pharmaceutical Calculations

Author : Mitchell J. Stoklosa

Publisher :

Page : 428 pages

File Size : 17,84 MB

Release : 1986

Category : Medical

ISBN : 9780812110074

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Book Description



The Specific Action of Drugs

Author : Alexander Burness

Publisher : BoD – Books on Demand

Page : 230 pages

File Size : 41,78 MB

Release : 2023-05-18

Category : Fiction

ISBN : 3382505584

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Book Description

Reprint of the original, first published in 1874. The publishing house Anatiposi publishes historical books as reprints. Due to their age, these books may have missing pages or inferior quality. Our aim is to preserve these books and make them available to the public so that they do not get lost.



A Primer of Drug Action

Author : Robert M. Julien

Publisher : Macmillan + ORM

Page : 755 pages

File Size : 15,45 MB

Release : 2013-08-06

Category : Health & Fitness

ISBN : 146685118X

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Book Description

Since 1975, Robert Julien's A Primer of Drug Action has been the definitive guide to the effects of psychoactive drugs on the brain and on behavior. Now fully updated, this popular guide continues to lead the way through a rapidly changing field, providing readers with a clear, contemporary, and objective look at every drug and medication that either positively or adversely affects brain function. This edition includes important new information on: -Herbal medications -Drug therapy for behavioral and anxiety disorders -Clinical practice guidelines for treating psychological disorders -Depression and the action of antidepressant drugs -The use of newer anticonvulsants in the treatment of bipolar disorder, pain syndromes, and behavioral disorders -Drug therapy for children, adolescents and the elderly -"New generation" antipsychotic agents Authoritative, comprehensive, and suitable for those with little background in biology, A Primer of Drug Action is an indispensable source of information for anyone interested in drug use, abuse, and education.



Medicinal Foods as Potential Therapies for Type-2 Diabetes and Associated Diseases

Author : Solomon Habtemariam

Publisher : Academic Press

Page : 1182 pages

File Size : 48,46 MB

Release : 2019-06-08

Category : Medical

ISBN : 0081029233

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Book Description

Medicinal Foods as Potential Therapies for Type-2 Diabetes and Associated Diseases: The Chemical and Pharmacological Basis of their Action focuses on active pharmacological principles that modulate diabetes, associated risk factors, complications and the mechanism of action of widely used anti-diabetic herbal plants—rather than just the nutritional composition of certain foods. The book provides up-to-date information on acclaimed antidiabetic super fruits, spices and other food ingredients. Sections cover diabetes and obesity at the global level, the physiological control of carbohydrate and lipid metabolism, the pathophysiology of type-2 diabetes, the chemistry and pharmacology of a variety of spices, and much more. This book will be invaluable for research scientists and students in the medical and pharmaceutical sciences, medicinal chemistry, herbal medicine, drug discovery/development, nutrition science, and for herbal practitioners and those from the nutraceutical and pharm industries. - Provides background knowledge on type-2 diabetes and its pathophysiology and therapeutic targets down to the molecular level - Explores, in detail, the chemistry or secondary metabolites of the indicated foods that potentially modify diabetes and/or associated diseases - Examines the pharmacological findings on medicinal foods, including available clinical trials



Drug Transporters

Author : Martin F. Fromm

Publisher : Springer Science & Business Media

Page : 457 pages

File Size : 22,37 MB

Release : 2010-11-19

Category : Medical

ISBN : 3642145418

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Book Description

It is increasingly recognized that various transporter proteins are expressed throughout the body and determine absorption, tissue distribution, biliary and renal elimination of endogenous compounds and drugs and drug effects. This book will give an overview on the transporter families which are most important for drug therapy. Most chapters will focus on one transporter family highlighting tissue expression, substrates, inhibitors, knock-out mouse models and clinical studies.