Thyroid Disease and Reproduction


Book Description

This book is a practical, evidence-based resource covering thyroid disease and its effects on reproduction and fertility, discussing thyroid function and dysfunction - hypothyroidism and hyperthyroidism, thyroid nodules and cancer - during pregnancy as well as its effects on the fetus. It begins with a review of the anatomy and function of the thyroid and the biosynthesis and physiology of thyroid hormones, as well as the pathophysiology of thyroid dysfunction. The chapters that follow discuss thyroid function and dysfunction (e.g., hypothyroidism and hyperthyroidism) during pregnancy and its effects on fertility as well as the developing fetus. The management of thyroid nodules and cancer, the role of thyroid dysfunction in infertility, the role of thyroid autoimmunity and miscarriage, and postpartum thyroiditis are presented in detail in the concluding chapters. Clinical cases and outcomes bookend each chapter, demonstrating current management strategies for a well-rounded presentation. Filling a clear gap in the literature usually covered only briefly in larger texts on the thyroid, Thyroid Disease and Reproduction: A Clinical Guide to Diagnosis and Management is a unique resource for reproductive endocrinologists, obstetrician/gynecologists, and residents and students in these clinical areas.




Mayo Clinic Guide to Fertility and Conception


Book Description

A helpful medical reference on conceiving and maintaining pregnancy from the Mayo Clinic, #1 on US News & World Report’s 2020-2021 Best Hospitals Honor Roll. Deciding to start or build a family is a life-changing decision. Once the decision is made, there’s a whole new set of unknowns—including whether the journey will be easy or difficult. How can you increase your chances of becoming pregnant? What health and lifestyle changes should you make to have a healthy pregnancy? And if you’re struggling to become pregnant, what medical treatments are available? Where can you get emotional support if you can’t get pregnant or if you’ve had a miscarriage? And when is enough? The fertility experts at Mayo Clinic offer answers to these questions and more. Through the pages of this book, they’ll guide you through the process of trying for—and achieving—a successful pregnancy. You’ll also hear throughout the book from couples and individuals who have struggled to have a family. For a variety of reasons—health conditions, unexplained infertility, or life circumstances—getting pregnant or deciding to have a family was difficult for them. These personal stories are to let you know that you’re not alone in your journey, and to give you hope that with time and patience, pregnancy is often possible. From lifestyle and dietary recommendations to understanding your ovulatory cycle to medications and procedures that can improve fertility, this book is a comprehensive source of answers from “one of the most reliable, respected health resources that Americans have” (Publishers Weekly).




Your Healthy Pregnancy with Thyroid Disease


Book Description

At minimum, 27 million Americans have thyroid disease. Despite being the majority of thyroid sufferers, women rarely know that thyroid problems increase their risk of pregnancy complications, including infertility, preeclampsia, miscarriage, premature delivery, and low birth weight. This awareness gap affects patients and doctors, who know little about the ramifications of an undiagnosed or under-treated thyroid condition on a mother and her unborn baby. Founder of HypothyroidMom.com Dana Trentini and thyroid health advocate and bestselling author Mary Shomon have both endured challenges with pregnancies due to thyroid disorders. In Your Healthy Pregnancy with Thyroid Disease, they team up to give readers the answers they need. With personal stories and cutting-edge medical advice from leading health practitioners, the book explains how to recognize thyroid symptoms, get properly diagnosed/treated, manage thyroid problems during pregnancy, overcome thyroid-related infertility, and deal with postpartum challenges.




70 Years of Levothyroxine


Book Description

This open access book presents the history, pharmacokinetics and pharmacodynamics of levothyroxine, discussing its role in the thyroid pathophysiology of patients of various ages and during pregnancy. It also describes the influence of levothyroxine on heart, bone and in cancer. When it was first synthesized in 1949, levothyroxine represented a significant advance in the treatment of hypothyroidism, providing a safe and effective treatment option for millions of hypothyroid patients around the globe. This synthetic form of thyroxine is now one of the most prescribed drugs in the world. Levothyroxine was first introduced by Merck KGaA,Darmstadt, Germany, in 1972, and since then the company has remained actively engaged in research on this mainstay of hypothyroidism treatment. This book is intended for healthcare professionals.




The thyroid and reproduction


Book Description




Clinical Gynecology


Book Description

Written with the busy practice in mind, this book delivers clinically focused, evidence-based gynecology guidance in a quick-reference format. It explores etiology, screening, tests, diagnosis, and treatment for a full range of gynecologic health issues. The coverage includes the full range of gynecologic malignancies, reproductive endocrinology and infertility, infectious diseases, urogynecologic problems, gynecologic concerns in children and adolescents, and surgical interventions including minimally invasive surgical procedures. Information is easy to find and absorb owing to the extensive use of full-color diagrams, algorithms, and illustrations. The new edition has been expanded to include aspects of gynecology important in international and resource-poor settings.




Thyroid Ultrasound


Book Description

This book is a wide-ranging and up-to-date guide to the use of ultrasound for imaging of the thyroid that will meet the needs of novices while providing more experienced professionals with advanced information. All of the techniques employed in modern thyroid ultrasound are covered, from conventional grayscale and Doppler imaging to elastography and contrast-enhanced ultrasound, with a focus on practical aspects and with detailed analysis of their diagnostic value and limitations. The characteristic ultrasound findings of the normal thyroid and a wide range of thyroid diseases and disorders are described with the aid of hundreds of high-quality images. Diffuse changes and thyroid lesions are discussed in depth, paying close attention to aspects of importance for early detection and differential diagnosis. In this context the authors summarize their personal experiences in the use of qualitative parameters of compression elastography and quantitative data of shear-wave elastography. In addition, a practical approach to the risk stratification of thyroid nodules is proposed. The book concludes with a resumé of the main challenges and pitfalls in thyroid ultrasound.




Endemic Cretinism


Book Description

Responding to a renewed interest in the growing problem of iodine deficiency worldwide, Drs. Charles Oxnard and Peter Obendorf, along with experienced translator and anatomist John Dennison, take a fresh look at the classic text, Der endemische Kretinismus, published in 1936 by Springer. Translated here for the first time into English, this landmark text will be a welcome resource for researchers confronting the problem of iodine deficiency. Oxnard and Obendorf point out that there is very little detailed knowledge or numerical data on cretinism available in the English-speaking world. In addition, highly-renowned Professor Basil S. Hetzel, recently-retired World Health Organization Chairman of the International Council for Control of Iodine Deficiency Disorders, published in 2009 with Dr Chen Zu-pei on the resurgence of iodine deficiency in China. Indeed, throughout the entire developing world there may be as many as two billion people at risk to iodine deficiency; perhaps three quarters of a billion have goiter, and ten million may be cretins. Even in developed countries, iodine deficiency is re-emerging (as in New South Wales in 19% of children) with the result of significantly reduced numbers of gifted children (though this is not cretinism per se). Certain to be of significant interest to a wide range of researchers, health providers and professionals, including government health administrators, this English translation of Endemic Cretinism is a major contribution to the literature.




Speroff's Clinical Gynecologic Endocrinology and Infertility


Book Description

One of the world's most widely read gynecology texts for nearly 50 years, Speroff ’s Clinical Gynecologic Endocrinology and Infertility provides a complete explanation of the female endocrine system and offers practical guidance for evaluation and treatment of common disorders. In this fully revised ninth edition, the editorial and author team from Yale School of Medicine have assumed the reins of Dr. Speroff’s landmark work, retaining the clear, concise writing style and illustrations that clarify and explain complex concepts. This classic text remains indispensable for students, residents, and clinicians working in reproductive endocrinology and infertility, bringing readers up to date with recent advances that have occurred in this fast-changing field.




Implantation and Early Development


Book Description

Successful implantation and early development need a union of healthy genes and an optimal uterine environment. The 48th RCOG Study Group, an international multidisciplinary expert forum, considered factors involved in preparation for implantation within the uterus; how to determine a good egg and good sperm; lessons from animal models; transgenic and genomic technologies; sporadic and recurrent early pregnancy loss; single-embryo transfer; and the developmental consequences of assisted reproduction technologies. This book presents the findings of the Study Group, with sections covering: • preparation for implantation - the uterine environment • the embryo • lessons from animal models (transgenics) and novel technologies • clinical sequelae.