The Treatment as Prevention(R) Empire


Book Description

Treatment as prevention® (TasP®) proposes a new way to end AIDS by requiring people living with HIV/AIDS (PWAs) to strictly adhere to lifelong HIV treatment, effectively making them non-infectious. Essentially, TasP attempts to stop the spread of HIV at the source. Yet, this radical prevention intervention is not without individual and collective repercussions. With an eye to the growing physical, moral, legal, and political costs of HIV treatment on adherence, this study seeks to describe how adherence has changed throughout the AIDS epidemic in order to understand its function in this present time and place of TasP in Vancouver. Through a Foucauldian genealogy, this dissertation examines how TasP adherence practices re-asserts colonial hierarchies. Guided by critical race and postcolonial theories, I argue that race and racism distinguish those who are made to live from those left to die in this new war on AIDS, a war against PWAs. Using biopower as an analytical framework, I emphasize the continued role of sovereign power, a repressive power alongside productive power. To examine adherence, I investigate specific moments in time and across place to ground Vancouver's current TasP rationale and practices, beginning with the scientific role and methods of late 19th century colonial medicine through to present day TasP. I delve into TasP's scientific rationale by analyzing the first uses of antiretroviral treatment for HIV prevention. Next, I outline the changes in British Columbia's public health law along with Vancouver's clinical guidelines and protocols. Then, I position artwork produced by PWAs as important sites of knowledge, providing insight into the multiple effects of antiretroviral therapy. To conclude, I argue that TasP works as an imperial formation as it uses force in the construction of its subjects. I suggest TasP pushes us to confront this ethical question: to what end and at whose expense are we willing to end AIDS? At its most basic level, this project seeks to disrupt the seemingly neutral scientific language of TasP by showing how scientific knowledge regarding adherence practices draw from histories relying on, recuperating, and revising the interlocking structures of colonialism, racism, sexism, poverty, and sexuality.




Malarial Subjects


Book Description

This book examines how and why British imperial rule shaped scientific knowledge about malaria and its cures in nineteenth-century India. This title is also available as Open Access.




Empire of Pain


Book Description

NEW YORK TIMES BESTSELLER • A NEW YORK TIMES NOTABLE BOOK OF THE YEAR • A grand, devastating portrait of three generations of the Sackler family, famed for their philanthropy, whose fortune was built by Valium and whose reputation was destroyed by OxyContin. From the prize-winning and bestselling author of Say Nothing. "A real-life version of the HBO series Succession with a lethal sting in its tail…a masterful work of narrative reportage.” – Laura Miller, Slate The history of the Sackler dynasty is rife with drama—baroque personal lives; bitter disputes over estates; fistfights in boardrooms; glittering art collections; Machiavellian courtroom maneuvers; and the calculated use of money to burnish reputations and crush the less powerful. The Sackler name has adorned the walls of many storied institutions—Harvard, the Metropolitan Museum of Art, Oxford, the Louvre. They are one of the richest families in the world, but the source of the family fortune was vague—until it emerged that the Sacklers were responsible for making and marketing a blockbuster painkiller that was the catalyst for the opioid crisis. Empire of Pain is the saga of three generations of a single family and the mark they would leave on the world, a tale that moves from the bustling streets of early twentieth-century Brooklyn to the seaside palaces of Greenwich, Connecticut, and Cap d’Antibes to the corridors of power in Washington, D.C. It follows the family’s early success with Valium to the much more potent OxyContin, marketed with a ruthless technique of co-opting doctors, influencing the FDA, downplaying the drug’s addictiveness. Empire of Pain chronicles the multiple investigations of the Sacklers and their company, and the scorched-earth legal tactics that the family has used to evade accountability. A masterpiece of narrative reporting, Empire of Pain is a ferociously compelling portrait of America’s second Gilded Age, a study of impunity among the super-elite and a relentless investigation of the naked greed that built one of the world’s great fortunes.




Herbal Medicine


Book Description

The global popularity of herbal supplements and the promise they hold in treating various disease states has caused an unprecedented interest in understanding the molecular basis of the biological activity of traditional remedies. Herbal Medicine: Biomolecular and Clinical Aspects focuses on presenting current scientific evidence of biomolecular ef




Saving Lives, Buying Time


Book Description

For more than 50 years, low-cost antimalarial drugs silently saved millions of lives and cured billions of debilitating infections. Today, however, these drugs no longer work against the deadliest form of malaria that exists throughout the world. Malaria deaths in sub-Saharan Africaâ€"currently just over one million per yearâ€"are rising because of increased resistance to the old, inexpensive drugs. Although effective new drugs called "artemisinins" are available, they are unaffordable for the majority of the affected population, even at a cost of one dollar per course. Saving Lives, Buying Time: Economics of Malaria Drugs in an Age of Resistance examines the history of malaria treatments, provides an overview of the current drug crisis, and offers recommendations on maximizing access to and effectiveness of antimalarial drugs. The book finds that most people in endemic countries will not have access to currently effective combination treatments, which should include an artemisinin, without financing from the global community. Without funding for effective treatment, malaria mortality could double over the next 10 to 20 years and transmission will intensify.




The Emperor of All Maladies


Book Description

Winner of the Pulitzer Prize and a documentary from Ken Burns on PBS, this New York Times bestseller is “an extraordinary achievement” (The New Yorker)—a magnificent, profoundly humane “biography” of cancer—from its first documented appearances thousands of years ago through the epic battles in the twentieth century to cure, control, and conquer it to a radical new understanding of its essence. Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with—and perished from—for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.




Crimes Committed by Terrorist Groups


Book Description

This is a print on demand edition of a hard to find publication. Examines terrorists¿ involvement in a variety of crimes ranging from motor vehicle violations, immigration fraud, and mfg. illegal firearms to counterfeiting, armed bank robbery, and smuggling weapons of mass destruction. There are 3 parts: (1) Compares the criminality of internat. jihad groups with domestic right-wing groups. (2) Six case studies of crimes includes trial transcripts, official reports, previous scholarship, and interviews with law enforce. officials and former terrorists are used to explore skills that made crimes possible; or events and lack of skill that the prevented crimes. Includes brief bio. of the terrorists along with descriptions of their org., strategies, and plots. (3) Analysis of the themes in closing arguments of the transcripts in Part 2. Illus.




The Spectrum Of Child Abuse


Book Description

First published in 1996. With so much information available today in the area of child abuse, figuring out where to begin quickly becomes overwhelming. But the Spectrum of Child Abuse stands out from current literature in its comprehensiveness and balance. Dr. Oates presents a detailed, thoroughly referenced overview of the entire field- rather than focusing exclusively on one particular professional viewpoint or facet of the problem. The chapters encompass physical abuse, sexual abuse, emotional abuse and neglect. For each of these areas, the text offers a clear historical perspective in addition to pertinent data on incidence and epidemiology, contributing factors, assessment, treatment and prevention. Moreover, a wealth of case studies underscores the important and meaning of various intervention strategies.




Rheumatology E-Book


Book Description

Covering both the scientific basis of rheumatology and practical, clinical information for rheumatologists and trainees, Rheumatology, 8th Edition, remains a leading text in this fast-changing field. Dr. Marc Hochberg and his team of worldwide editors and authors keep you abreast of recent advances in the field— all in a user-friendly, accessible manner. Fully updated from cover to cover, this two-volume text is designed to meet the needs of all practicing and academic rheumatologists as well as arthritis-related health care professionals and scientists interested in rheumatic and musculoskeletal diseases. Covers the epidemiology, pathogenesis, clinical manifestations, therapeutic approach, and management of all major as well as rarely encountered rheumatic and musculoskeletal diseases. Discusses clinical examination, imaging principles, differential diagnosis, established and novel therapies, perioperative evaluation, pain management, basic science, and genetics of rheumatic and musculoskeletal diseases. Uses a consistent, logical, reader-friendly format with templated chapters, concise text, and large-scale, state-of-the-art illustrations for efficient visual reference. Contains new chapters covering pre-clinical disease and how to address these patients, common comorbidities in rheumatoid arthritis; emerging therapies for systemic sclerosis; immune mediated complications of checkpoint inhibitors; the epidemiology of COVID-19 and rheumatic and musculoskeletal diseases, emerging treatments for osteoarthritis, and big data analytics. Provides updates to key topics such as systems biology and its impact on our understanding of the pathogenesis of rheumatic and musculoskeletal diseases, the microbiome in rheumatic musculoskeletal diseases, how to manage chronic pain in the patient with a rheumatic disease, drugs and reproductive health, and emerging therapies for patients with RA, SLE, spondyloarthritis, inflammatory muscle disease, and vasculitis. Shares the knowledge and expertise of numerous new contributing authors, as well as new co-editor Dr. Désirée van der Heijde, who is an expert in psoriatic arthritis, spondyloarthritis, imaging, and clinical epidemiology. Provides access to concise videos depicting the use of ultrasound for diagnosis and treatment. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices. If you encounter issues with your eBook please contact Elsevier eBook+ support via [email protected].




‘Ending AIDS’ in the Age of Biopharmaceuticals


Book Description

This book considers the change in rhetoric surrounding the treatment of AIDS from one of crisis to that of ‘ending AIDS’. Exploring what it means to ‘end AIDS’ and how responsibility is framed in this new discourse, the author considers the tensions generated between the individual and the state in terms of notions such as risk, responsibility and prevention. Based on analyses public health promotions in the UK and the US, HIV prevention science and engaging with the work of Foucault, this volume argues that the discourse of ‘ending AIDS’ implies a tension-filled space in which global principles and values may clash with localised needs, values and concerns; in which evidence-based policies strive for hegemony over local, tacit and communal regimes of knowledge; and in which desires compete with national and international ideas about what is best for the individual in the name of ‘ending AIDS’ writ large. As such, it will appeal to scholars of sociology and media studies with interests in the sociology of medicine and health, medical communication and health policy.