Pharmaceutical and Biomedical Project Management in a Changing Global Environment


Book Description

Pharmaceutical and Biomedical Portfolio Management in a Changing Global Environment explores some of the critical forces at work today in the complex endeavour of pharmaceutical and medical product development. Written by experienced professionals, and including real-world approaches and best practice examples, this new title addresses three key areas – small molecules, large molecules, and medical devices - and provides hard-to-find, consolidated information relevant to and needed by pharmaceutical, biotech, and medical device company managers.




Monte Carlo Simulation for the Pharmaceutical Industry


Book Description

Helping you become a creative, logical thinker and skillful "simulator," Monte Carlo Simulation for the Pharmaceutical Industry: Concepts, Algorithms, and Case Studies provides broad coverage of the entire drug development process, from drug discovery to preclinical and clinical trial aspects to commercialization. It presents the theories and metho




Journal of Applied Operational Research


Book Description

We are pleased to welcome readers to this issue of the Journal of Applied Operational Research (JAOR), Volume 5, Number 3. The journal reports on developments in all aspects of operational research, including the latest advances and applications. It is a primarily goal of the journal to focus on and publish practical case studies which illustrate real-life applications.




Project Valuation and Decision Making under Risk and Uncertainty applying Decision Tree Analysis and Monte Carlo Simulation


Book Description

This work presents the application of the Monte Carlo Simulation method and the Decision Tree Analysis approach when dealing with the economic valuation of projects which are subjected to risks and uncertainties. The Net Present Value of a project is usually used as an investment decision parameter. Using deterministic models to calculate a project’s Net Present Value neglects the risky and uncertain nature of real life projects and consequently leads to useless valuation results. Realistic valuation models need to use probability density distributions for the input parameters and certain probabilities for the occurrence of specific events during the life time of a project in combination with the Monte Carlo Simulation method and the Decision Tree Analysis approach. After a short introduction a brief explanation of the traditional project valuation methods is given. The main focus of this work lies in using the Net Present Value method as a basic valuation tool in conjunction with the Monte Carlo Simulation technique and the Decision Tree Analysis approach to form a comprehensive method for project valuation under risk and uncertainty. The extensive project valuation methodology introduced is applied on two fictional projects, one from the pharmaceutical sector and one from the oil and gas exploration and production industry. Both industries deal with high risks, high uncertainties and high costs, but also high rewards. The example from the pharmaceutical industry illustrates very well how the application of the Monte Carlo Simulation and Decision Tree Analysis method, results in a well-diversified portfolio of new drugs with the highest reward at minimum possible risk. Applying the presented probabilistic project valuation approach on the oil exploration and production project shows how to reduce the risk of losing big.




Evaluation and Performance Measurement of Research and Development


Book Description

This book develops and illustrates a comprehensive, multi-level framework for the evaluation of industrial research and development (R&D) activities and the measurement of their performance. The framework encompasses a set of hierarchical, interrelated levels at which R&D evaluation and performance measurement could be undertaken. This enlightening book focuses on the single industrial firm to study performance measurement of R&D functions, projects and individual researchers or engineers. It also addresses R&D evaluation from the point of view of financial markets, with a focus on the relationship between R&D investments and the value of the traded firm. The book broadens tin scope to study the role of technology platforms as R&D coordination mechanisms and also looks at the evaluation of R&D policies. This book will be warmly welcomed by researchers and postgraduate students in disciplines concerned with innovation management, technology policy, and finance who wish to gain an updated overview of R&D evaluation and performance measurement as well as exploring different units of analysis.




QFINANCE: The Ultimate Resource, 4th edition


Book Description

QFINANCE: The Ultimate Resource (4th edition) offers both practical and thought-provoking articles for the finance practitioner, written by leading experts from the markets and academia. The coverage is expansive and in-depth, with key themes which include balance sheets and cash flow, regulation, investment, governance, reputation management, and Islamic finance encompassed in over 250 best practice and thought leadership articles. This edition will also comprise key perspectives on environmental, social, and governance (ESG) factors -- essential for understanding the long-term sustainability of a company, whether you are an investor or a corporate strategist. Also included: Checklists: more than 250 practical guides and solutions to daily financial challenges; Finance Information Sources: 200+ pages spanning 65 finance areas; International Financial Information: up-to-date country and industry data; Management Library: over 130 summaries of the most popular finance titles; Finance Thinkers: 50 biographies covering their work and life; Quotations and Dictionary.




Ebook: Principles of Corporate Finance


Book Description

Ebook: Principles of Corporate Finance




Flexibility


Book Description

We are in an era of high volatility and uncertain outcomes, driven by accelerating technologies, shortened product cycles, fast-changing information, an increasingly mobile workforce, more demanding customers, complex financial markets, ad-hoc public policies, and many other factors that add layers of uncertainty to all future possibilities. In an information- and knowledge-driven environment with high levels of uncertainty, most traditional ideas of structure, system, and strategy are ineffective. This book shows how to create, maintain, and accelerate an organization in a highly uncertain environment using flexibility. It analyzes the organization holistically and details its primary components independently. The author presents an economic framework of decision options to diagnose existing flexibility problems and provides guidance on how to improve flexibility and reduce risk. The text also describes how to design and maintain a high performance organization for the long run in an environment of high uncertainty.




Accelerating Performance


Book Description

Transform your organization into a dynamic catalyst for success Accelerating Performance is not just another “warm and fuzzy” change management book—it's a practical, comprehensive, data-driven action plan for picking up the pace and achieving more. Co-written by one of the authors of Beyond Performance, this book draws on a combination of empirical research and decades of experience advising global companies to show you how to reduce time to value by building and changing momentum more quickly than your competitors. The META framework (short for Mobilize, Execute, and Transform with Agility) offers advice for leading change at four levels: strategy, the organization, teams, and individuals. In addition to step-by-step guidance toward assessment, planning, and implementation, the book offers: A diagnostic tool for leaders, teams, and organizations to assess their starting place, and highlight the specific areas needed to improve the ability to accelerate performance. A detailed look at the factors proven to create drag—and drive—at each of the four levels: strategy, organizations, teams, and individuals. An exploration of the 39 differentiating actions that organizations can combine as dictated by their strategy and context into a winning recipe. A closer look at the practices of 23 “superaccelerators,” a global (and perhaps unexpected) mix of companies that have demonstrated a consistent ability to accelerate performance. A single taste of success is all it takes to spark change, but the hard work of following through requires constant vigilance—and a plan. Learn how to capture that drive, bottle it, and use it to sustain motivation, inspiration, and achievement. Deliver at the highest level, and then turn around and do even better next time. Accelerating Performance gives leaders a step-by-step framework for taking action and transforming their organizations, teams, and even themselves—starting today.




Portfolio, Program, and Project Management in the Pharmaceutical and Biotechnology Industries


Book Description

This book describes the way that pharmaceutical projects and programs are currently managed, and offers views from many highly experienced practitioners from within the industry on future directions for drug program management. The book integrates portfolio, program, and project management processes as fundamental for effective and efficient drug product development. Contributing expert authors provide their view of how the projectization approach can be taken forward by the drug industry over the coming years.