The Virus Paradigm


Book Description

In recent years, the word 'virus' has lost its biological perimeter of reference to acquire a much broader – could say 'paradigmatic' – meaning. The term 'virus' can be seen as a key word or an explanatory model also for processes that go beyond the infectious sphere. Every event appears to have a viral character: from the way information is transmitted to the processes of cultural globalization, from the impact of human beings on the planet to the subversion of ecosystems, from pandemic risks to the demographic increase on the planet. This seems to be indeed the Age of the Virus. Its model can be applied to most of the phenomena that characterize the twenty-first. Its profile – its looming and invisible nature, its ability to use other people's resources to spread and to transform into a dangerous doppelganger – is perfect to represent the fears of the contemporary age.




Virus Assembly and Exit Pathways


Book Description

Advances in Virus Research, Volume 108, in this ongoing series, highlights new advances in the field, with this new volume presenting interesting chapters on topics including Virus infections of the developing brain, Geminivirus assembly, Flavivirus assembly, Cell-cell transmission, Archael virus assembly, Potyvirus assembly, Poxvirus assembly and exit, Mycovirus assembly, Reo/orbivirus assembly and exit, Giant virus assembly, Quasi-enveloped virus assembly/exit, and Betaherpesvirus assembly and exit. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Advances in Virus Research series - Includes the latest information on virus assembly and exit pathways




Post-Pandemic Pedagogy


Book Description

Post-Pandemic Pedagogy: A Paradigm Shift discusses how the COVID-19 pandemic radically altered teaching and learning for faculty and students alike. The increased prevalence of video-conferencing software for conducting classes fundamentally changed the way in which we teach and seemingly upended many best practices for good pedagogy in the college classroom. Whether it was the reflection over surveillance software, or the increased mental health demands of the pandemic on teachers and students, or the completely reshaped ways in which classes and co-curricular experiences were delivered, the pandemic year represented an opportunity for one of the largest shifts in our understanding of good pedagogy unlike any experienced in the modern era. This edited collection explores what we thought we knew about a variety of teaching ideas, how the pandemic changed our approach to them, and proposes ways in which some of the adjustments made to accommodate the pandemic will remain for years to come. Scholars of communication, pedagogy, and education will find this book particularly interesting.




Pandemic


Book Description

"Interweaving history, original reportage, and personal narrative, Pandemic explores the origins of epidemics, drawing parallels between the story of cholera-- one of history's most disruptive and deadly pathogens-- and the new pathogens that stalk humankind today"--




The Threat of Pandemic Influenza


Book Description

Public health officials and organizations around the world remain on high alert because of increasing concerns about the prospect of an influenza pandemic, which many experts believe to be inevitable. Moreover, recent problems with the availability and strain-specificity of vaccine for annual flu epidemics in some countries and the rise of pandemic strains of avian flu in disparate geographic regions have alarmed experts about the world's ability to prevent or contain a human pandemic. The workshop summary, The Threat of Pandemic Influenza: Are We Ready? addresses these urgent concerns. The report describes what steps the United States and other countries have taken thus far to prepare for the next outbreak of "killer flu." It also looks at gaps in readiness, including hospitals' inability to absorb a surge of patients and many nations' incapacity to monitor and detect flu outbreaks. The report points to the need for international agreements to share flu vaccine and antiviral stockpiles to ensure that the 88 percent of nations that cannot manufacture or stockpile these products have access to them. It chronicles the toll of the H5N1 strain of avian flu currently circulating among poultry in many parts of Asia, which now accounts for the culling of millions of birds and the death of at least 50 persons. And it compares the costs of preparations with the costs of illness and death that could arise during an outbreak.




Fevers, Feuds, and Diamonds


Book Description

“Paul Farmer brings his considerable intellect, empathy, and expertise to bear in this powerful and deeply researched account of the Ebola outbreak that struck West Africa in 2014. It is hard to imagine a more timely or important book.” —Bill and Melinda Gates "[The] history is as powerfully conveyed as it is tragic . . . Illuminating . . . Invaluable." —Steven Johnson, The New York Times Book Review In 2014, Sierra Leone, Liberia, and Guinea suffered the worst epidemic of Ebola in history. The brutal virus spread rapidly through a clinical desert where basic health-care facilities were few and far between. Causing severe loss of life and economic disruption, the Ebola crisis was a major tragedy of modern medicine. But why did it happen, and what can we learn from it? Paul Farmer, the internationally renowned doctor and anthropologist, experienced the Ebola outbreak firsthand—Partners in Health, the organization he founded, was among the international responders. In Fevers, Feuds, and Diamonds, he offers the first substantive account of this frightening, fast-moving episode and its implications. In vibrant prose, Farmer tells the harrowing stories of Ebola victims while showing why the medical response was slow and insufficient. Rebutting misleading claims about the origins of Ebola and why it spread so rapidly, he traces West Africa’s chronic health failures back to centuries of exploitation and injustice. Under formal colonial rule, disease containment was a priority but care was not – and the region’s health care woes worsened, with devastating consequences that Farmer traces up to the present. This thorough and hopeful narrative is a definitive work of reportage, history, and advocacy, and a crucial intervention in public-health discussions around the world.




Contagious Ideas


Book Description

Neo-Darwinism is becoming an increasingly important influence on archaeological theory, as a number of recently edited books on `Darwinian archaeologies' make clear. However, many of these volumes are internationally inconsistent and reflect the muddled understanding many archaeologists have of the potential of Darwin's thought for interpreting material culture. Ben Cullen's book starts by critiquing some recent neo-Darwinist approaches, including cultural evolutionism and cultural sociobiology. He then presents a neo-Darwinian paradigm of extreme power, which he has termed the Cultural Virus Theory (CVT). This focuses on explaining the transmission of ideas by comparing cultural memes wit natural genes. In the final section he takes the important step of applying this theory to real materials; demonstrating how CVT can be used to understand the spread of megalithic monuments in prehistoric North-West Europe, the diffusion of the renaissance in medieval Europe and the basis of stylistic change in pottery. Tragically this collection of brilliant thoughts is published posthumously. Ben Cullen was close to finishing a major book when he died suddenly in 1995 and his writings have been gathered into a consistent whole by James Steele, Richard Cullen and Christopher Chippendale.




SARS, MERS and other Viral Lung Infections


Book Description

Viral respiratory tract infections are important and common causes of morbidity and mortality worldwide. In the past two decades, several novel viral respiratory infections have emerged with epidemic potential that threaten global health security. This Monograph aims to provide an up-to-date and comprehensive overview of severe acute respiratory syndrome, Middle East respiratory syndrome and other viral respiratory infections, including seasonal influenza, avian influenza, respiratory syncytial virus and human rhinovirus, through six chapters written by authoritative experts from around the globe.




The Stockholm Paradigm


Book Description

The contemporary crisis of emerging disease has been a century and a half in the making. Human, veterinary, and crop health practitioners convinced themselves that disease could be controlled by medicating the sick, vaccinating those at risk, and eradicating the parts of the biosphere responsible for disease transmission. Evolutionary biologists assured themselves that coevolution between pathogens and hosts provided a firewall against disease emergence in new hosts. Most climate scientists made no connection between climate changes and disease. None of these traditional perspectives anticipated the onslaught of emerging infectious diseases confronting humanity today. As this book reveals, a new understanding of the evolution of pathogen-host systems, called the Stockholm Paradigm, explains what is happening. The planet is a minefield of pathogens with preexisting capacities to infect susceptible but unexposed hosts, needing only the opportunity for contact. Climate change has always been the major catalyst for such new opportunities, because it disrupts local ecosystem structure and allows pathogens and hosts to move. Once pathogens expand to new hosts, novel variants may emerge, each with new infection capacities. Mathematical models and real-world examples uniformly support these ideas. Emerging disease is thus one of the greatest climate change–related threats confronting humanity. Even without deadly global catastrophes on the scale of the 1918 Spanish Influenza pandemic, emerging diseases cost humanity more than a trillion dollars per year in treatment and lost productivity. But while time is short, the danger is great, and we are largely unprepared, the Stockholm Paradigm offers hope for managing the crisis. By using the DAMA (document, assess, monitor, act) protocol, we can “anticipate to mitigate” emerging disease, buying time and saving money while we search for more effective ways to cope with this challenge.




Flu


Book Description

Veteran journalist Gina Kolata's Flu: The Story of the Great Influenza Pandemic of 1918 and the Search for the Virus That Caused It presents a fascinating look at true story of the world's deadliest disease. In 1918, the Great Flu Epidemic felled the young and healthy virtually overnight. An estimated forty million people died as the epidemic raged. Children were left orphaned and families were devastated. As many American soldiers were killed by the 1918 flu as were killed in battle during World War I. And no area of the globe was safe. Eskimos living in remote outposts in the frozen tundra were sickened and killed by the flu in such numbers that entire villages were wiped out. Scientists have recently rediscovered shards of the flu virus frozen in Alaska and preserved in scraps of tissue in a government warehouse. Gina Kolata, an acclaimed reporter for The New York Times, unravels the mystery of this lethal virus with the high drama of a great adventure story. Delving into the history of the flu and previous epidemics, detailing the science and the latest understanding of this mortal disease, Kolata addresses the prospects for a great epidemic recurring, and, most important, what can be done to prevent it.