Thyroid Cancer: Current Diagnosis, Management, and Prognostication, An Issue of Otolaryngologic Clinics of North America


Book Description

This Otolaryngologic Clinics' publication’s intent is to provide standard and state of the art clinician performed thyroid ultrasound and ultrasound guided FNA technique. The subject area is evolving rapidly with new technologies being incorporated. This title integrates thyroid cytology, FNA and Ultrasound Guided FNA with inclusion of diagnostic molecular testing. Clinical Thyroid Molecular Testing has ushered in a new era to the diagnosis, management and prognostication of thyroid nodules. The discussion of this highly clinically applicable subject is described in terms of diagnostic process. This is a thyroid neoplasm clinical “game changer for the General Otolaryngologist, Head and Neck Surgeon, General Surgeon, Endocrinologist, Pathologist, and Radiologist. This testing maximizes the number of patients who have cancer to receive the correct therapeutic surgery appropriately and minimizes the number of patients who do not need surgery (and avoid the potential complications and surgery) because they do not have cancer. Surgical management and prognostication have far reaching implications with fine needle aspiration driven molecular markers. Some topics include: Clinical evaluation of the thyroid nodule; Thyroid cytology; Clinician performed thyroid ultrasound; Clinician performed thyroid ultrasound guided FNA; Thyroid cancer molecular laterations - what the surgeon should know; Thyroid cancer multi-gene expression - what the surgeon needs to know; Incorporating molecular testing into your thyroid practice - five experts discuss; and others.




Thyroid Cancer: Current Diagnosis, Management, and Prognostication, An Issue of Otolaryngologic Clinics of North America


Book Description

This Otolaryngologic Clinics' publication's intent is to provide standard and state of the art clinician performed thyroid ultrasound and ultrasound guided FNA technique. The subject area is evolving rapidly with new technologies being incorporated. This title integrates thyroid cytology, FNA and Ultrasound Guided FNA with inclusion of diagnostic molecular testing. Clinical Thyroid Molecular Testing has ushered in a new era to the diagnosis, management and prognostication of thyroid nodules. The discussion of this highly clinically applicable subject is described in terms of diagnostic process. This is a thyroid neoplasm clinical "game changer” for the General Otolaryngologist, Head and Neck Surgeon, General Surgeon, Endocrinologist, Pathologist, and Radiologist. This testing maximizes the number of patients who have cancer to receive the correct therapeutic surgery appropriately and minimizes the number of patients who do not need surgery (and avoid the potential complications and surgery) because they do not have cancer. Surgical management and prognostication have far reaching implications with fine needle aspiration driven molecular markers. Some topics include: Clinical evaluation of the thyroid nodule; Thyroid cytology; Clinician performed thyroid ultrasound; Clinician performed thyroid ultrasound guided FNA; Thyroid cancer molecular laterations - what the surgeon should know; Thyroid cancer multi-gene expression - what the surgeon needs to know; Incorporating molecular testing into your thyroid practice - five experts discuss; and others.




Ear Implants, An Issue of Otolaryngologic Clinics of North America


Book Description

Guest Editors Colin L. Driscoll and Brian A. Neff have brought together leading experts to review the current state of active middle ear implants. This issue of Otolaryngologic Clinics will explore the history of device development to aid in understanding what has led to successful platforms. Articles in this issue include: Sound Transfer of Active Middle Ear Implants; Historical Development of Active Middle Ear Implants; Vibrant Soundbridge Rehabilitation of Conductive and Mixed Hearing Loss; Vibrant Soundbridge Rehabilitation of Sensorineural Hearing Loss; The Envoy Esteem Implantable Hearing System; Implantable Hearing Devices: The Ototronix MAXUM System; and Otologics Active Middle Ear Implants.




Common ENT Disorders in Children, An Issue of Otolaryngologic Clinics of North America


Book Description

National health statistics indicate that pediatric ear, nose, and throat disorders remain among the primary reasons children visit a physician, with ear infections ranking as the number one reason. From earaches to choking hazards, from nosebleeds to speech irregularities, children can present with a variety of problems that cause concern to parents and caregivers, who want prompt diagnosis and treatment. The presentation of topics in this issue is clinically ppropriate for Otolaryngologists, Pediatricians, Allergy specialists, and Family Physicians. Topics in this issue of Otolaryngologic Clinics include: Hearing screening and hearing loss; Acute otitis media; Chronic adenotonsilitis; Pediatric dysphagia; Lymphadenopathy; Rhinosinusitis; Facial trauma; Sialadenitis; Behavior and otolaryngology; Stridor; Otolaryngologic management of severe neurodevelopmental delay; Pediatric craniofacial problems.




Pediatric Head and Neck Masses, An Issue of Otolaryngologic Clinics of North America


Book Description

Experts from childrens' hospitals across the United States discuss diagnosis, treatment, and pathophysiology of head and neck masses in children. Topics include: Branchial cleft cysts; Thyroglossal duct cyst and ectopic thyroid; Vascular malformations; Thyroid nodule and malignancy in children; Lymphoma in pediatrics; Malignancies in the pediatric head and neck - rhabdomyosarcoma and neuroblastoma; Skull base and more including intranasal masses; Tumors of the maxsilla and mandible; Teratoma and dermoid cysts; Inflammatory adenopathy; Disorders and tumors of the salivary glands; Intraoral and lingual lesions; and the Exit procedure. Beyond relevance to Otolaryngologists, this issue of Otolaryngologic Clinics is appropriate for cancer specialists, pediatricians, family practitioners, general surgeons, and pediatric nurse practitioners. Residents training in those fields, as well as Neurosurgery and Ophthalmology, will find this practical.




Endocrine Pathology, An Issue of Surgical Pathology Clinics


Book Description

Early identification and diagnosis by type and stage is the key to high survival rates with thyroid cancer. To present the pathologist with current clinical information on diagnosis, differential diagnosis, staging, and prognosis of thyroid cancers, topics presented are: Poorly differentiated thyroid carcinoma; Paraganglimoa; Immunohistochemical markers for evaluation and prognosis in thyroid carcinoma; Familial endocrine syndromes; Parathyroid enoplasia; Inflammatory lesions of the thyroid associated with cancer; Assessing biological aggression in adrenal cortical neoplasia; Pituitary neoplasia; and Pancreatic endocrine neoplasia. Peter Sadow, whose clinical practice and research involve studying the mechanisms of endocrine carcinogenesis through translational studies involving the proteomics and genomics of endocrine neoplasms, primarily of the thyroid and adrenal glands, leads this issue.




Tumors of the Ear and Lateral Skull Base: Part 1, An Issue of Otolaryngologic Clinics of North America


Book Description

The Editors for this issue of Otolaryngologic Clinics, Dr George Wanna and Dr Matthew Luke Carlson, envisioned a publication that reviews the evaluation and management of common ear and lateral skull base tumors. Intended audience includes Otologists, Neurotologists, General otolaryngologists and Neurosurgeons alike. The development of management of lateral skull base tumors has been rapid, in the past 40 years there has been a tremendous shift toward conservative therapy for benign lesions. Focused chapters review specific pathologies plus a chapter focused on stereotactic radiotherapy. Topics written by reputed leaders in the field of Otology and skull base tumors include: Imaging of temporal bone lesions; Squamous cell carcinoma of the temporal bone; Glomus tympanicum; Adenomatous tumors of the middle ear; Intralabyrinthine schwannomas; Vestibular schwannoma; Neurofibromatosis2 (including ABI and CI); Non-schwannoma tumors of the CPA; Glomus jugulare; Endolymphatic sac tumors; Non-paraganglioma jugular foramen tumors; Primary tumors of the facial nerve; Cholesterol granuloma and other petrous apex lesions; Stereotactic radiosurgery for tumors of the lateral skull base; Pediatric temporal bone malignancy; and Historical perspective on evolution in management of lateral skull base tumors.




The Bethesda System for Reporting Thyroid Cytopathology


Book Description

This atlas is the offspring of the “The National Cancer Institute (NCI) Thyroid Fine Needle Aspiration (FNA) State of the Science Conference,” hosted by the NCI and organized by Dr. Andrea Abati. Preparations for the conference began 18 months earlier with the designation of a steering committee and the establishment of a dedicated, p- manent web site. The meeting took place on October 22 and 23, 2007 in Bethesda, Maryland and was co-moderated by Susan J. Mandel and Edmund S. Cibas. The discussions and conclusions regarding terminology and morphologic criteria 1, 2 from the meeting were summarized in publications by Baloch et al. and form the framework for this atlas. The atlas is organized by the general categories of “Nondiagnostic,” “Benign,” “Follicular Neoplasm/Suspicious for a Follicular Neoplasm”, “Suspicious for Malignancy,” and “Malignant,” and it includes the defi- tions and morphologic criteria of these categories as set forth by Baloch et al. The majority of the conference participants also agreed on a category of “undetermined significance,” which is incorporated in this atlas (Chap. 4). It is critical that the cytopathologist communicate thyroid FNA interpretations to the referring physician in terms that are succinct, unambiguous, and helpful clinically. We recognize that the terminology used here is a flexible framework that can be modified by individual laboratories to meet the needs of their providers and the patients they serve.




AJCC Cancer Staging Manual


Book Description

The American Joint Committee on Cancer's Cancer Staging Manual is used by physicians throughout the world to diagnose cancer and determine the extent to which cancer has progressed. All of the TNM staging information included in this Sixth Edition is uniform between the AJCC (American Joint Committee on Cancer) and the UICC (International Union Against Cancer). In addition to the information found in the Handbook, the Manual provides standardized data forms for each anatomic site, which can be utilized as permanent patient records, enabling clinicians and cancer research scientists to maintain consistency in evaluating the efficacy of diagnosis and treatment. The CD-ROM packaged with each Manual contains printable copies of each of the book’s 45 Staging Forms.




Improving Diagnosis in Health Care


Book Description

Getting the right diagnosis is a key aspect of health care - it provides an explanation of a patient's health problem and informs subsequent health care decisions. The diagnostic process is a complex, collaborative activity that involves clinical reasoning and information gathering to determine a patient's health problem. According to Improving Diagnosis in Health Care, diagnostic errors-inaccurate or delayed diagnoses-persist throughout all settings of care and continue to harm an unacceptable number of patients. It is likely that most people will experience at least one diagnostic error in their lifetime, sometimes with devastating consequences. Diagnostic errors may cause harm to patients by preventing or delaying appropriate treatment, providing unnecessary or harmful treatment, or resulting in psychological or financial repercussions. The committee concluded that improving the diagnostic process is not only possible, but also represents a moral, professional, and public health imperative. Improving Diagnosis in Health Care, a continuation of the landmark Institute of Medicine reports To Err Is Human (2000) and Crossing the Quality Chasm (2001), finds that diagnosis-and, in particular, the occurrence of diagnostic errorsâ€"has been largely unappreciated in efforts to improve the quality and safety of health care. Without a dedicated focus on improving diagnosis, diagnostic errors will likely worsen as the delivery of health care and the diagnostic process continue to increase in complexity. Just as the diagnostic process is a collaborative activity, improving diagnosis will require collaboration and a widespread commitment to change among health care professionals, health care organizations, patients and their families, researchers, and policy makers. The recommendations of Improving Diagnosis in Health Care contribute to the growing momentum for change in this crucial area of health care quality and safety.