Time-dependent Structure and Control of Arterial Blood Pressure


Book Description

This work focuses on the time-related aspects of blood pressure monitoring, the temporal distribution of cardiovascular events and the implication that these have for the pharmacologic control of hypertension; a possible rationale of a chronotherapeutic approach to this disease is offered.




Chronomics and Continuous Ambulatory Blood Pressure Monitoring


Book Description

This fascinating volume applies the concept of chronomics to the medical treatment of hypertension. It starts with the recent updates on chronomics, the analytic techniques, and their application to community-based assessments. The authors advocate the use of 7-day/24-h records of blood pressure, which is effective for finding masked hypertension, masked morning surge, and other rhythm abnormalities. Most organisms, from cyanobacteria to mammals, are known to use the circadian mechanism. However, our body systems also demonstrate circaseptan (roughly weekly), circannual (roughly yearly), and even longer rhythms. Chronomics monitors the physiological data and then analyzes the superimposed rhythms, isolating the cycles mathematically to determine how organisms and their environment interact. It is the study of interactions among time structures (chronomes) in and around us.




Frontiers of Blood Pressure and Heart Rate Analysis


Book Description

An increasing number of studies indicate that the analysis of blood pressure and heart rate variability may be a valuable tool for the investigation of the mechanisms responsible for cardiovascular regulation in physiological and pathological conditions. The reader can find in the first part of this book an updated review of the techniques currently employed for the computer analysis of these signals with a particular attention to the most innovative approaches based on the non-linear analysis (including applications of the chaos theory, fractal analysis, I/f modelling) and the time-variant estimation of BP and HR characteristics. The biological interpretation of the results obtained by these computerized procedures and the applicability of these techniques in a clinical setting are fully addressed in the second part of the book.




Perspectives in Hypertension


Book Description

This book strikes a fine balance between contemporary Continuing Medical Education Articles and original research work related to cardiovascular system in general and hypertension in particular. Highlights of this edition include: (a) Addressing common clinical problems of Hypertension management. (b) Outlining Patho-physiological aspects of Hypertension. (c) Making management of various co-morbidities with hypertension very simple by providing simple, well defined algorithms and flow charts. (d) Studies on Bio-rhythms and circadian rhythms.




From Molecule to Men


Book Description

From molecule to man: Medical research has indeed taken this direction, and major improvements of our understanding of the pathophysiology and epidemiology of disease have been achieved. The molecular basis of the congenital cardiovascular disorders has been extended from relatively few congenital malformations into everyday illnesses such as diabetes mellitus, hyperlipoproteinaemea, and arterial hypertension. The monogenic and, more difficult, polygenic basis for a vast majority of cardiovascular disorders are being defined more precisely from year to year. This book gives an overview of what has been achieved so far and defines the current position.







Arterial Stiffness in Hypertension


Book Description

Main headings: I. Basic concepts of pulsatile arterial hemodynamics. - II. Pathophysiological mechanisms. - III. Arterial stiffness, wave reflections, cardiovascular risk and end-organ damage. - IV. Clinical aspects of arterial stiffness and wave reflections. - V. Therapeutic aspects of arterial stiffness and wave reflections.




Blood Pressure Monitoring in Cardiovascular Medicine and Therapeutics


Book Description

Blood Pressure Monitoring in Cardiovascular Medicine and Therapeutics provides information that will be especially useful to all who care for hyperten sive patients. The various chapters provide a full account of the mounting sci entific evidence that blood pressure recordings need to be obtained for proper diagnosis, prognosis, and therapy for these patients. The contributors are each directly involved in clinical studies ofhome and ambulatory blood pressure moni toring, as well as of the relationship of circadian variations in heart rate and blood pressure to cardiovascular events. As a longtime observer of the multiple facets of clinical hypertension, I have been greatly impressed with the rapid advances in this area over the last two decades. Out-of-office blood pressure monitoring has grown from a curi osity to a necessity. In order to improve the currently inadequate control of hypertension throughout the world, such monitoring should become routine in the diagnosis and treatment of every patient. The evidence for the role of out-of-office monitoring that is so well described in Blood Pressure Monitoring in Cardiovascular Medicine and Therapeutics should serve as a stimulus for the more widespread adoption of the procedure. Once this is understood, the constraints on the broader clinical use of ambulatory monitoring that now exist in the United States will be lifted as the value of such information becomes more generally recognized. In the meantime, self-recorded home measurements should be more widely utilized.




The Body Clock Guide to Better Health


Book Description

A medical breakthrough explained by the leading authority on the connection between health and your body clock Chronotherapy-adjusting the care of the body to coincide with the body's natural clock-is poised to be the next major revolution in medical science. An understanding and awareness of these rhythms will enable us to maximize the effects not only of medications and other treatments, but also of diets, exercise programs, and other daily routines. The Body Clock Guide to Better Health combines a detailed discussion of major issues such as sleep, exercise, and nutrition, with a comprehensive A-to-Z reference to specific disorders. Among the health concerns it addresses are AIDS, arthritis, asthma, ADD, backache, cancer, depression, diabetes, digestive problems, allergies, heart disease, chronic pain, sexual dysfunction, stroke, and complications from pregnancy. General chapters explore the big picture-including monthly cycles and life cycles-and provide invaluable advice on foods and dietary supplements, fitness, better sex, jet lag, and more. The first book to look at body rhythms from a practical perspective, The Body Clock Guide to Better Health offers readers the dual benefits of improving the treatment of specific conditions while boosting their overall health and wellness.




Pediatric Hypertension


Book Description

The importance of hypertension in children and adolescents is becoming incre- ingly recognized by physicians and scientists in the 21st century. However, in contrast to the attention that hypertension has received in the adult population for the past three decades since the first Joint National Committee (JNC) report, research and clinical knowledge that involves hypertension in children is still very much in its own childhood. Pediatric Hypertension, edited by Drs. Portman, Sorof, and Ingelfinger, is undoubtedly the most up-to-date and clinically relevant contribution to the field of hypertension in children available because it brings together the numerous pathophysiologic, diagnostic, and therapeutic advances in the evaluation of high blood pressure in infants, children, and adolescents. The editors have carefully organized their volume into sections that cover blood pressure regulation in infants and children, blood pressure measurement issues, pat- physiology and clinical assessment for essential and secondary forms of hypertension during childhood, and nonpharmacologic and pharmacologic approaches to the tre- ment of hypertension in children.