Toxicological Profile for Chloromethane
Author :
Publisher :
Page : 264 pages
File Size : 38,86 MB
Release : 1998
Category : Methyl chloride
ISBN :
Author :
Publisher :
Page : 264 pages
File Size : 38,86 MB
Release : 1998
Category : Methyl chloride
ISBN :
Author :
Publisher :
Page : 108 pages
File Size : 14,82 MB
Release : 1989
Category : Ethyl chloride
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Author : Arthur L. Frank
Publisher :
Page : 60 pages
File Size : 48,97 MB
Release : 2001
Category : Environmental monitoring
ISBN :
Author :
Publisher :
Page : 180 pages
File Size : 41,82 MB
Release : 1992
Category : Ethylene dibromide
ISBN :
Author : Obaid Faroon
Publisher : DIANE Publishing
Page : 497 pages
File Size : 26,52 MB
Release : 2010-08
Category : Medical
ISBN : 1437930670
DDT is a pesticide that was once widely used to control insects. Both DDD and DDE are breakdown products of DDT. This profile includes: (1) The examination, summary, and interpretation of available toxicologic info. and epidemiologic evaluations on DDT/DDD/DDE to ascertain the levels of significant human exposure for the substance and the associated chronic health effects; (2) A determination of whether adequate info. on the health effects of DDT/DDD/DDE is available to determine levels of exposure that present a significant risk to human health of chronic health effects; and (3) Identification of toxicologic testing needed to identify the types or levels of exposure that may present significant risk of adverse health effects in humans. Illus.
Author :
Publisher :
Page : 164 pages
File Size : 46,81 MB
Release : 1998
Category : Chloroethane
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Author :
Publisher :
Page : 190 pages
File Size : 15,70 MB
Release : 1994
Category : 1,1,2,2-Tetrachloroethane
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Author : Andrew Teasdale
Publisher : John Wiley & Sons
Page : 548 pages
File Size : 22,62 MB
Release : 2022-02-15
Category : Medical
ISBN : 1119551218
Learn to implement effective control measures for mutagenic impurities in pharmaceutical development In Mutagenic Impurities: Strategies for Identification and Control, distinguished chemist Andrew Teasdale delivers a thorough examination of mutagenic impurities and their impact on the pharmaceutical industry. The book incorporates the adoption of the ICH M7 guideline and focuses on mutagenic impurities from both a toxicological and analytical perspective. The editor has created a primary reference for any professional or student studying or working with mutagenic impurities and offers readers a definitive narrative of applicable guidelines and practical, tested solutions. It demonstrates the development of effective control measures, including chapters on the purge tool for risk assessment. The book incorporates a discussion of N-Nitrosamines which was arguably the largest mutagenic impurity issue ever faced by the pharmaceutical industry, resulting in the recall of Zantac and similar drugs resulting from N-Nitrosamine contamination. Readers will also benefit from the inclusion of: A thorough introduction to the development of regulatory guidelines for mutagenic and genotoxic impurities, including a historical perspective on the development of the EMEA guidelines and the ICH M7 guideline An exploration of in silico assessment of mutagenicity, including use of structure activity relationship evaluation as a tool in the evaluation of the genotoxic potential of impurities A discussion of a toxicological perspective on mutagenic impurities, including the assessment of mutagenicity and examining the mutagenic and carcinogenic potential of common synthetic reagents Perfect for chemists, analysts, and regulatory professionals, Mutagenic Impurities: Strategies for Identification and Control will also earn a place in the libraries of toxicologists and clinical safety scientists seeking a one-stop reference on the subject of mutagenic impurity identification and control.
Author : Bruce Anderson
Publisher : Elsevier
Page : 6651 pages
File Size : 16,62 MB
Release : 2005-05-31
Category : Medical
ISBN : 0080548008
The second edition of the Encyclopedia of Toxicology continues its comprehensive survey of toxicology. This new edition continues to present entries devoted to key concepts and specific chemicals. There has been an increase in entries devoted to international organizations and well-known toxic-related incidents such as Love Canal and Chernobyl. Along with the traditional scientifically based entries, new articles focus on the societal implications of toxicological knowledge including environmental crimes, chemical and biological warfare in ancient times, and a history of the U.S. environmental movement. With more than 1150 entries, this second edition has been expanded in length, breadth and depth, and provides an extensive overview of the many facets of toxicology. Also available online via ScienceDirect – featuring extensive browsing, searching, and internal cross-referencing between articles in the work, plus dynamic linking to journal articles and abstract databases, making navigation flexible and easy. For more information, pricing options and availability visit www.info.sciencedirect.com. *Second edition has been expanded to 4 volumes *Encyclopedic A-Z arrangement of chemicals and all core areas of the science of toxicology *Covers related areas such as organizations, toxic accidents, historical and social issues, and laws *New topics covered include computational toxicology, cancer potency factors, chemical accidents, non-lethal chemical weapons, drugs of abuse, and consumer products and many more!
Author : J. Descotes
Publisher : Elsevier
Page : 859 pages
File Size : 43,88 MB
Release : 1996-09-02
Category : Technology & Engineering
ISBN : 0080534228
This excellent volume was designed and edited with two major ideas in mind: firstly, the field of clinical toxicology is changing and an acknowledgement of these changes is warranted; secondly, no comprehensive compilation of recently published case reports of, and clinical studies on, human poisonings is available, which is in sharp contrast to the closely related field of drug-induced side-effects.The book focusses on issues of recent concern, or issues poorly documented in the past. It is important that clinical toxicologists gain a better knowledge of all the available techniques of toxicological analysis. A better understanding of the way a sound interpretation of results should be conducted for the benefit of the patient's management, and a comprehensive set of data on the kinetics of the most common pharmaceutical drugs and many chemicals is required.Human Toxicology is a timely reference work which will be welcomed by a broad audience of toxicology professionals.