Toxicological Profile for Polycyclic Aromatic Hydrocarbons
Author :
Publisher :
Page : 500 pages
File Size : 20,89 MB
Release : 1995
Category : Polycyclic aromatic hydrocarbons
ISBN :
Author :
Publisher :
Page : 500 pages
File Size : 20,89 MB
Release : 1995
Category : Polycyclic aromatic hydrocarbons
ISBN :
Author : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans
Publisher : IARC Monographs on the Evaluat
Page : 0 pages
File Size : 23,71 MB
Release : 2013
Category : Medical
ISBN : 9789283213246
This volume of the IARC Monographs provides an assessment of the carcinogenicity of 18 chemicals present in industrial and consumer products or food (natural constituents, contaminants, or flavorings) or occurring as water-chlorination by-products. The compounds evaluated include the widely used plasticizer di(2-ethylhexyl) phthalate and the food contaminant 4-methylimidazole. In view of the limited agent-specific information available from epidemiological studies, the IARC Monographs Working Group relied mainly on carcinogenicity bioassays, and mechanistic and other relevant data to evaluate the carcinogenic hazards to humans exposed to these agents.
Author : Obaid Faroon
Publisher : DIANE Publishing
Page : 497 pages
File Size : 33,91 MB
Release : 2010-08
Category : Medical
ISBN : 1437930670
DDT is a pesticide that was once widely used to control insects. Both DDD and DDE are breakdown products of DDT. This profile includes: (1) The examination, summary, and interpretation of available toxicologic info. and epidemiologic evaluations on DDT/DDD/DDE to ascertain the levels of significant human exposure for the substance and the associated chronic health effects; (2) A determination of whether adequate info. on the health effects of DDT/DDD/DDE is available to determine levels of exposure that present a significant risk to human health of chronic health effects; and (3) Identification of toxicologic testing needed to identify the types or levels of exposure that may present significant risk of adverse health effects in humans. Illus.
Author :
Publisher :
Page : 186 pages
File Size : 37,6 MB
Release : 1993
Category : Diethylhexyl phthalate
ISBN :
Author :
Publisher :
Page : 348 pages
File Size : 43,8 MB
Release : 2002
Category : Diethylhexyl phthalate
ISBN :
Author : National Research Council
Publisher : National Academies Press
Page : 208 pages
File Size : 32,36 MB
Release : 2009-01-19
Category : Nature
ISBN : 0309128412
People are exposed to a variety of chemicals throughout their daily lives. To protect public health, regulators use risk assessments to examine the effects of chemical exposures. This book provides guidance for assessing the risk of phthalates, chemicals found in many consumer products that have been shown to affect the development of the male reproductive system of laboratory animals. Because people are exposed to multiple phthalates and other chemicals that affect male reproductive development, a cumulative risk assessment should be conducted that evaluates the combined effects of exposure to all these chemicals. The book suggests an approach for cumulative risk assessment that can serve as a model for evaluating the health risks of other types of chemicals.
Author :
Publisher :
Page : 340 pages
File Size : 22,10 MB
Release : 1997
Category : Trichloroethylene
ISBN :
Author :
Publisher :
Page : 300 pages
File Size : 35,1 MB
Release : 2000
Category : Phthalate esters
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Author :
Publisher :
Page : 296 pages
File Size : 46,2 MB
Release : 2000
Category : DI(2-ethylhexyl) phthalate
ISBN :
Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
Page : 423 pages
File Size : 28,17 MB
Release : 2017-08-14
Category : Science
ISBN : 0309458625
To safeguard public health, the US Environmental Protection Agency (EPA) must keep abreast of new scientific information and emerging technologies so that it can apply them to regulatory decision-making. For decades the agency has dealt with questions about what animal-testing data to use to make predictions about human health hazards, how to perform dose-response extrapolations, how to identify and protect susceptible subpopulations, and how to address uncertainties. As alternatives to traditional toxicity testing have emerged, the agency has been faced with additional questions about how to incorporate data from such tests into its chemical assessments and whether such tests can replace some traditional testing methods. Endocrine active chemicals (EACs) have raised concerns that traditional toxicity-testing protocols might be inadequate to identify all potential hazards to human health because they have the ability to modulate normal hormone function, and small alterations in hormone concentrations, particularly during sensitive life stages, can have lasting and significant effects. To address concerns about potential human health effects from EACs at low doses, this report develops a strategy to evaluate the evidence for such low-dose effects.