Author : National Research Council
Publisher : National Academies Press
Page : 393 pages
File Size : 46,77 MB
Release : 1980-02-01
Category : Medical
ISBN : 0309030447
Author : Maria Boekels Gogarten
Publisher : Humana Press
Page : 0 pages
File Size : 43,46 MB
Release : 2009-03-11
Category : Science
ISBN : 9781603278522
Horizontal gene transfer (HGT) events encompass processes as varied as the exchange of genetic material between microbes coexisting in the same environment, between symbiotic bacteria and their eukaryotic hosts, and the evolution of organelles by symbiosis, in which whole genomes are acquired. In Horizontal Gene Transfer: Genomes in Flux, expert researchers contribute an overview of HGT concepts as well as specific case histories that highlight the most current progress to inspire future work. Divided into three sections, the volume begins with an overview of terminology, concepts and the implications of HGT on current evolutionary thought and philosophy, and continues with methods involving computer and bioinformatics analyses of genomic data as well as molecular biology techniques for identifying, quantifying, and differentiating instances of HGT. A section of case studies follows, which provides detailed accounts of how HGT has shaped evolution across the diversity of organisms and organismal lineages. As a volume of the highly successful Methods in Molecular BiologyTM series, this work provides the kind of detailed description and implementation advice that is crucial for getting optimal results. Cutting-edge and thoroughly detailed, Horizontal Gene Transfer: Genomes in Flux examines how HGT has contributed to genome evolution and how understanding HGT impacts our ability to accurately reconstruct and comprehend the web-like evolutionary history in order to aid scientists in furthering their own research.
Author : Eva-Maria Bernoth
Publisher : Elsevier
Page : 545 pages
File Size : 31,82 MB
Release : 1997-01-29
Category : Science
ISBN : 0080532225
Furunculosis: Multidisciplinary Fish Disease Research presents a fascinating insight into the opinions and the controversies which have led to current knowledge of this disease. It is the first book to cover one single fish disease by presenting not just the reviews, but also critical examination of the progress made by various disciplines. The multidisciplinary approach of the book makes it a valuable guide for veterinarians, fisheries biologists, and fish farm managers, as well as an excellent instructional text for students. The volume explores current research strategies and projects what developments can be expected in each field. - Considers the whole disease and not just the pathogen, Aeromonas salmonicida - Analyzes the state of modern knowledge on the disease - Suggests topics for future research and uses furunculosis as a model for other diseases - Highlights and summarizes each section's themes and concepts - Presents a unique compendium of research information for all professionals working on furunculosis
Author : Boyan B. Bonev
Publisher : John Wiley & Sons
Page : 288 pages
File Size : 14,71 MB
Release : 2019-06-10
Category : Science
ISBN : 111994077X
AN AUTHORITATIVE SURVEY OF CURRENT RESEARCH INTO CLINICALLY USEFUL CONVENTIONAL AND NONCONVENTIONAL ANTIBIOTIC THERAPEUTICS Pharmaceutically-active antibiotics revolutionized the treatment of infectious diseases, leading to decreased mortality and increased life expectancy. However, recent years have seen an alarming rise in the number and frequency of antibiotic-resistant "Superbugs." The Centers for Disease Control and Prevention (CDC) estimates that over two million antibiotic-resistant infections occur in the United States annually, resulting in approximately 23,000 deaths. Despite the danger to public health, a minimal number of new antibiotic drugs are currently in development or in clinical trials by major pharmaceutical companies. To prevent reverting back to the pre-antibiotic era—when diseases caused by parasites or infections were virtually untreatable and frequently resulted in death—new and innovative approaches are needed to combat the increasing resistance of pathogenic bacteria to antibiotics. Bacterial Resistance to Antibiotics – From Molecules to Man examines the current state and future direction of research into developing clinically-useful next-generation novel antibiotics. An internationally-recognized team of experts cover topics including glycopeptide antibiotic resistance, anti-tuberculosis agents, anti-virulence therapies, tetracyclines, the molecular and structural determinants of resistance, and more. Presents a multidisciplinary approach for the optimization of novel antibiotics for maximum potency, minimal toxicity, and appropriated degradability Highlights critical aspects that may relieve the problematic medical situation of antibiotic resistance Includes an overview of the genetic and molecular mechanisms of antibiotic resistance Addresses contemporary issues of global public health and longevity Includes full references, author remarks, and color illustrations, graphs, and charts Bacterial Resistance to Antibiotics – From Molecules to Man is a valuable source of up-to-date information for medical practitioners, researchers, academics, and professionals in public health, pharmaceuticals, microbiology, and related fields.
Author : Gerry Wright
Publisher : Wiley
Page : 384 pages
File Size : 31,55 MB
Release : 2016-08-22
Category : Science
ISBN : 9781118376737
Author : José-Luis Capelo-Martínez
Publisher : John Wiley & Sons
Page : 730 pages
File Size : 38,36 MB
Release : 2019-09-24
Category : Medical
ISBN : 1119282527
This book presents a thorough and authoritative overview of the multifaceted field of antibiotic science – offering guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases. Provides readers with knowledge about the broad field of drug resistance Offers guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases Links strategies to analyze microbes to the development of new drugs, socioeconomic impacts to therapeutic strategies, and public policies to antibiotic-resistance-prevention strategies
Author : Derek J. Chadwick
Publisher : John Wiley & Sons
Page : 260 pages
File Size : 50,63 MB
Release : 2008-04-30
Category : Medical
ISBN : 0470515368
Antibiotic Resistance: Origins, Evolution, Selection and Spread Chairman: Stuart B. Levy, 1997 Over the last 50 years, the rapid increase in the use of antibiotics, not only in people, but also in animal husbandry and agriculture, has delivered a selection unprecedented in the history of evolution. Consequently, society is facing one of its gravest public health problems-the emergence of infectious bacteria with resistance to many, and in some cases all, available antibiotics. This book brings together a multidisciplinary group of experts to discuss this problem. It begins by examining the origins of resistance and goes on to look at how the use of antibiotics in human medicine and farming/agriculture has selected for resistant bacteria. Separate chapters describe the evolution of resistance determinants and how these are spread both within and between bacterial species. Finally, the book contains discussions on strategies for countering the threat of antibiotic resistance. A major re-thinking of our approach to the treatment of infectious diseases is proposed-that antibiotic resistance should be seen as a problem created by the disruption of normal microbial ecology. To restore efficacy to earlier antibiotics, and to maintain the success of new antibiotics that are introduced, we need to use these drugs in a way that ensures an ecological balance that favours the predominance of susceptible bacteria.
Author : Majeti Narasimha Vara Prasad
Publisher : Butterworth-Heinemann
Page : 530 pages
File Size : 35,65 MB
Release : 2020-02-07
Category : Technology & Engineering
ISBN : 0128187840
Waterborne Pathogens: Detection and Treatment delivers the tools and techniques on how to identify these contaminates and apply the most effective technology for their removal and treatment. Written for researchers and practicing professionals, the book starts with a brief, but readable, review of ubiquitous waterborne pathogens (primarily viruses, bacterial and parasitic protozoa). This coverage is followed by an in-depth discussion of the latest detection and treatment technologies, ranging from Biosensors, to Nanoconjugates, Membrane Based Technologies and Nanotechnology Treatment. Engineers and scientist will find this to be a valuable reference on cutting-edge techniques for suppling safe drinking water across the globe. - Explains the latest research on detection, treatment processes and remediation technologies - Includes sampling, analytical and characterization methods and approaches - Covers cutting-edge research, including Membrane Based Technologies, Nanotechnology Treatment Technologies and Bioremediation Treatment Technologies - Provides background information regarding contamination sources
Author : Odo Diekmann
Publisher : Princeton University Press
Page : 517 pages
File Size : 14,72 MB
Release : 2012-11-18
Category : Science
ISBN : 1400845629
Mathematical modeling is critical to our understanding of how infectious diseases spread at the individual and population levels. This book gives readers the necessary skills to correctly formulate and analyze mathematical models in infectious disease epidemiology, and is the first treatment of the subject to integrate deterministic and stochastic models and methods. Mathematical Tools for Understanding Infectious Disease Dynamics fully explains how to translate biological assumptions into mathematics to construct useful and consistent models, and how to use the biological interpretation and mathematical reasoning to analyze these models. It shows how to relate models to data through statistical inference, and how to gain important insights into infectious disease dynamics by translating mathematical results back to biology. This comprehensive and accessible book also features numerous detailed exercises throughout; full elaborations to all exercises are provided. Covers the latest research in mathematical modeling of infectious disease epidemiology Integrates deterministic and stochastic approaches Teaches skills in model construction, analysis, inference, and interpretation Features numerous exercises and their detailed elaborations Motivated by real-world applications throughout
Author : Jun Lin
Publisher : Frontiers Media SA
Page : 226 pages
File Size : 11,7 MB
Release : 2015-06-01
Category : Antibiotics
ISBN : 2889195260
Antibiotics represent one of the most successful forms of therapy in medicine. But the efficiency of antibiotics is compromised by the growing number of antibiotic-resistant pathogens. Antibiotic resistance, which is implicated in elevated morbidity and mortality rates as well as in the increased treatment costs, is considered to be one of the major global public health threats (www.who.int/drugresistance/en/) and the magnitude of the problem recently prompted a number of international and national bodies to take actions to protect the public (http://ec.europa.eu/dgs/health_consumer/docs/road-map-amr_en.pdf: http://www.who.int/drugresistance/amr_global_action_plan/en/; http://www.whitehouse.gov/sites/default/files/docs/carb_national_strategy.pdf). Understanding the mechanisms by which bacteria successfully defend themselves against the antibiotic assault represent the main theme of this eBook published as a Research Topic in Frontiers in Microbiology, section of Antimicrobials, Resistance, and Chemotherapy. The articles in the eBook update the reader on various aspects and mechanisms of antibiotic resistance. A better understanding of these mechanisms should facilitate the development of means to potentiate the efficacy and increase the lifespan of antibiotics while minimizing the emergence of antibiotic resistance among pathogens.
