Translational Acupuncture Research


Book Description

Written by many scientists and clinicians from China, USA, Canada and other countries, this monograph discusses translational research on acupuncture. Besides general topics on acupuncture practice (e.g., different styles and techniques of acupuncture), topics include some refractory diseases such as chronic fatigue syndrome, Parkinson’s disease, cardiovascular dysfunction, chronic pain, post-concussion syndrome and post-traumatic stress disorder and cancer-related symptoms. The factors influencing acupuncture research are comprehensively addressed in the final chapter. This unique book provides a translational perspective on modern acupuncture for not only acupuncturists, but also neuroscientists, neurologists, and other clinicians. For medical students and undergraduate and graduate students majoring in biology, this book is an advanced course for learning the progress in alternative and complementary Medicine.




Current Research in Acupuncture


Book Description

Written by over 60 scientists and clincicians from the United States, mainland China, Germany, Australia, Japan, Sweden, Portugal and Hong Kong, Current Research in Acupuncture discusses recent advances in acupuncture research in a modern scientific language. The first 5 chapters investigate the basic mechanisms of acupuncture. Later chapters explore topics including acupuncture treatment and potential mechanisms for epilepsy, Parkinson’s diseases, neurodegenerative disorders such as Alzheimer’s disease, vascular cognitive impairment, aging, anxiety, polycystic ovary syndrome, pain, nerve root cervical spondylosis, stroke, imflamation, myocardial ischemia and other cardiovascular diseases. Following the translational and clinical discussions, 4 chapters present new prospects for acupuncture theories and applications. The final chapter comments on the pitfalls and problems of the previous studies and suggests direction for future research towards in-depth understanding of acupuncture, along with better application of acupuncture in modern medicine. Each chapter is written by one or more experts in the field. This unique book provides a broad perspective on the principles of acupuncture for acupuncture researchers and neuroscientists. The laboratory and clinical investigations of various acupoints and optimal conditions provide unique clues to acupuncturists for improved clinical efficacy. For a medical student, this book is a modern course in ancient Traditional Chinese Medicine, especially acupuncture. Ying Xia, the chief editor, is Professor and Vice-Chairman of the Department of Neurosurgery at The University of Texas Medical School in Houston, Texas, USA. Guanghong Ding is Professor in the Department of Mechanics and Engineering Science at Fudan University and Director of Shanghai Research Center for Acupuncture and Meridians, Shanghai, China. Gen-Cheng Wu is Professor of Neurobiology; Chairman, Department of Integrative Medicine and Neurobiology; Director, Institute of Acupuncture Research; and Director, WHO Collaborating Center for Traditional Medicine, at Shanghai Medical College of Fudan University, Shanghai, China.




Acupuncture Research


Book Description

This is the first book to set out a full range of research strategies for evaluating the clinical practice of acupuncture. Leading acupuncturists and researchers with international reputations share their expertise. They illustrate their descriptions with practical examples of what has worked and what has not. It outlines many of the key challenges in the field. These challenges relate to the nature of acupuncture and the gap between current research evidence and the actual experiences of acupuncturists in the field. By focusing the chapters on key research questions, rather than methods, the book has a user-friendly feel. Each chapter is easily accessible with brief explanations of research designs as well as vignettes of relevant past research. The book is based on a deep understanding of acupuncture, with its inherent complexity in practice, whether based on traditional principles or more modern concepts. By incorporating a more sophisticated understanding of the field, this book details a range of strategies aiming to develop the evidence base with the utmost rigour. It is the first book on acupuncture research to take this unique view, integrating the very best of evidence-based medicine with a genuine sensitivity to the discipline of acupuncture, from its traditional and holistic roots to its more modern interpretations.




Methods and Applications of Longitudinal Data Analysis


Book Description

Methods and Applications of Longitudinal Data Analysis describes methods for the analysis of longitudinal data in the medical, biological and behavioral sciences. It introduces basic concepts and functions including a variety of regression models, and their practical applications across many areas of research. Statistical procedures featured within the text include: - descriptive methods for delineating trends over time - linear mixed regression models with both fixed and random effects - covariance pattern models on correlated errors - generalized estimating equations - nonlinear regression models for categorical repeated measurements - techniques for analyzing longitudinal data with non-ignorable missing observations Emphasis is given to applications of these methods, using substantial empirical illustrations, designed to help users of statistics better analyze and understand longitudinal data. Methods and Applications of Longitudinal Data Analysis equips both graduate students and professionals to confidently apply longitudinal data analysis to their particular discipline. It also provides a valuable reference source for applied statisticians, demographers and other quantitative methodologists. - From novice to professional: this book starts with the introduction of basic models and ends with the description of some of the most advanced models in longitudinal data analysis - Enables students to select the correct statistical methods to apply to their longitudinal data and avoid the pitfalls associated with incorrect selection - Identifies the limitations of classical repeated measures models and describes newly developed techniques, along with real-world examples.




Neural Substrates of Acupuncture: from Peripheral to Central Nervous System Mechanisms


Book Description

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.




Acupuncture Therapy for Neurological Diseases


Book Description

Acupuncture therapy has been practiced in China and other Asian countries for more than two thousand years. Modern clinical research has confirmed the impressive therapeutic effect of acupuncture on numerous human ailments, such as controlling pain, nausea, and vomiting. However, the biological mechanisms of acupuncture are still under debate. In Traditional Chinese Medicine (TCM), the mechanism of acupuncture therapy is explained by a meridian model. According to this model, acupuncture is believed to treat the diseased organs by modulating two conditions known as Yin and Yang, which represent all the opposite principles that people find in the universe, both inside and outside the human body. Yin and Yang complement each other, and are subjected to changes between each other. The balance of Yin and Yang is thought to be maintained by Qi, an energy substance flowing constantly through the meridian, a network connecting all the organs of the body. The illness, according to this theory, is the temporary dominance of one principle over the other, owing to the blockade of the Qi from flowing through the meridian under certain circumstance. The axiom of “No stagnation, No pain” in TCM summarizes this concept. Thus, the goal of acupuncture treatment is to restore the balance of Yin and Yang conditions in the diseased organ(s). This theory has been considered to be useful to guide this ancient therapy, such as carrying out diagnosis, deciding on the principle, and selecting the acupoints.




WHO Standard Acupuncture Point Locations in the Western Pacific Region


Book Description

Acupuncture has been practiced for more than 2500 years in the Western Pacific region and has become a global therapeutic method in recent decades. However, it was reported that acupuncturists differed by up to 25% in the acupuncture points they used, raising doubts and uncertainty regarding the efficacy and safety of acupuncture treatment, as well as causing difficulties in the fields of acupuncture research and education. Member States therefore increasingly began to demand standardization in acupuncture point locations. Responding to this request, the WHO Western Pacific Regional Office initiated a project to reach consensus on acupuncture point locations and thus convened 11 serial meetings resulting in these guidelines. This Standard acupuncture point locations in the Western Pacific Region stipulates the methodology for locating acupuncture points on the surface of the human body, as well as the locations of 361 acupuncture points. The Standard is applicable for teaching, research, clinical service, publication, and academic exchanges involving acupuncture.




The Harvard Medical School Guide to Tai Chi


Book Description

A longtime teacher and Harvard researcher presents the latest science on the benefits of T’ai Chi as well as a practical daily program for practitioners of all ages Conventional medical science on the Chinese art of T’ai Chi now shows what T’ai Chi masters have known for centuries: regular practice leads to more vigor and flexibility, better balance and mobility, and a sense of well-being. Cutting-edge research from Harvard Medical School also supports the long-standing claims that T’ai Chi also has a beneficial impact on the health of the heart, bones, nerves and muscles, immune system, and the mind. This research provides fascinating insight into the underlying physiological mechanisms that explain how T’ai Chi actually works. Dr. Peter M. Wayne, a longtime T’ai Chi teacher and a researcher at Harvard Medical School, developed and tested protocols similar to the simplified program he includes in this book, which is suited to people of all ages, and can be done in just a few minutes a day. This book includes: • The basic program, illustrated by more than 50 photographs • Practical tips for integrating T’ai Chi into everyday activities • An introduction to the traditional principles of T’ai Chi • Up-to-date summaries of the research on the health benefits of T’ai Chi • How T’ai Chi can enhance work productivity, creativity, and sports performance • And much more




Translational Pain Research: Comparing preclinical studies and clinical pain management. Lost in translation?


Book Description

Basic science and clinical pain research is particularly challenging for several reasons. First, pain is a subjective experience in response to nociception that follows actual or potential tissue damage. Since the ability to respond to this warning signal is essential for our survival, the nociceptive system that produces and transmits nociceptive signals is remarkably redundant and involves diffuse regions of the central nervous system. Second, unlike other sensory modalities, pain is a multi-dimensional experience including at least cognitive, affective, and sensory-discriminative components. Third, pain experiences can be influenced by psychological, socioeconomic, cultural, and genetic predispositions, making it exceedingly complicated to study pain and pain modulation. The topics covered in this volume are carefully selected and directly related to the daily practice of pain medicine. These topics include 1) central mechanisms of pain and pain modulation (Dickenson, Donovan-Rodriguez, Mattews) and clinical use of ion channel blockers (Chen); 2) spinal glutamatergic mechanisms (Guo, Dubner, Ren) and issues related to glutamate receptor antagonists in pain management (Mao); 3) basic science of opioid analgesics (Gintzler, Chakrabarti) and clinical opioid use (Smith, McCleane); 4) inflammatory cytokines (Samad) and clinical use of anti-inflammatory drugs (Fink, Brenner); 5) role of the sympathetic nervous system in pain mechanisms and its relation to clinical pain management (Sharma, Raja); 6) preclinical studies on tricyclic antidepressants (Gerner, Wang) and clinical use of antidepressants in pain management (Greenberg); 7) developing pain pathways and analgesic mechanisms during the developmental stage (Fitzgerald) and challenges of pediatric pain management (Lebel); 8) basic science mechanisms of serotonin agonists and their use in the clinical management of migraine headache (Biondi); 9) clinical research on gender differences in clinical pain and their implications for clinical pain management (Holdcroft); 10) current modalities of clinical cancer pain management (Popescu, Hord); and 11) preclinical and clinical information on alternative medicine (Chen).