Author : Charles W. Hewitt
Publisher : Springer Science & Business Media
Page : 490 pages
File Size : 19,77 MB
Release : 2007-12-20
Category : Medical
ISBN : 038774682X
This brilliant synthesis summarizes all of the recent accomplishments – as well as the ongoing research – in the field of composite tissue transplantation. It includes sections on hand transplantation and vascularized bone marrow transplantation. The volume focuses on immunology and the biotechnology/bioengineering aspects of transplantation surgery, as those two areas have demonstrated the most growth within the last five years in terms of current research.
Author : Nadey S Hakim
Publisher : World Scientific
Page : 305 pages
File Size : 38,90 MB
Release : 2006-05-05
Category : Medical
ISBN : 1911299247
The first textbook of its kind dealing with composite tissue allograft and allograft transplantation, provides an excellent overview on the subject. It provides a clear description of the current status of the transplant of every composite tissue allograft already performed and others which are still at the basic experimental level.The editors of the book, who also contribute chapters in their expertise, are world renowned surgeons. This book opens with an introductory chapter on the history of this type of transplantation and then details the clinical experience in each graft such as hand, larynx, face, uterus and the related histopathology, immunosuppression and immunomodulation.A multidisciplinary and comprehensive presentation of the various aspects of this new area of transplantation will allow the reader to understand the complexity and the challenges of composite tissue transplantation. A number of important topics are analyzed and discussed in detail, such as the ethical, medicolegal, psychological and immunological implications. New rehabilitation techniques and strategies, together with innovative tools for the functional evaluation of the transplanted parts, are highlighted. A section on the experimental work underlines what lies ahead of us./a
Author : Jean-Michel Dubernard
Publisher : MIT Press
Page : 132 pages
File Size : 39,94 MB
Release : 2002
Category : Medical
ISBN : 9782742004157
Transplanting hands -- a model of composite tissue grafting -- began in Lyons in November 1998 with the transplant of one hand and then, in January 2000, of two, both with the support of the Mérieux Foundation. Advances in immunosuppression made possible some unusual transplants of tissue, such as bones, knee-joints, femurs and larynx. From these stemmed the first attempts to transplant hands. This book looks at the long-term results of reattaching hands that have been accidentally amputated. It reviews all the problems -- technical, immunological, nervous, functional and psychological -- that surgeons encountered during and after the transplants. Surgeons, transplant experts, immunologists, dermatologists, psychiatrists, neurophysiologists, physiotherapists and re-education experts will also find here answers to their ethical and legal questions about removing tissue from donors, as well as information about composite tissue grafts in plastic and reconstructive surgery.
Author : Nadey Hakim
Publisher : Springer Science & Business Media
Page : 468 pages
File Size : 31,94 MB
Release : 2001-03-10
Category : Medical
ISBN : 9781852332860
It is like a fairy story! Or at least a beautiful epic, a truly significant page in the history of medicine, a staggering scene in which several actors come into play, both fundamentalists and clinical practitioners, eager to place all these new developments at the disposal of those suffering from ill health. Everyone is passionate about their work, be it providing new knowledge or perfecting new therapeutic methods. Man has always been fascinated by the possibility of replacing a damaged organ with a healthy one. Several attempts have been made over the centuries, and some miracles have been reported, such as those of Saint Damien and Saint Come as illustrated by Fra Angelico. The modern saga, however, started more modestly on the mouse. It is on the mouse that the first tissue group was discovered; yet the study of human tissue groups could only be carried out on a human. One human must be subjected to the thousands of tests that have enabled us to unravel the extraordinary complexity of the HLA system.
Author : Giuseppe Orlando
Publisher : Academic Press
Page : 1050 pages
File Size : 29,60 MB
Release : 2013-10-11
Category : Science
ISBN : 012398520X
Regenerative Medicine Applications in Organ Transplantation illustrates exactly how these two fields are coming together and can benefit one another. It discusses technologies being developed, methods being implemented, and which of these are the most promising. The text encompasses tissue engineering, biomaterial sciences, stem cell biology, and developmental biology, all from a transplant perspective. Organ systems considered include liver, renal, intestinal, pancreatic, and more. Leaders from both fields have contributed chapters, clearly illustrating that regenerative medicine and solid organ transplantation speak the same language and that both aim for similar medical outcomes. The overall theme of the book is to provide insight into the synergy between organ transplantation and regenerative medicine. Recent groundbreaking achievements in regenerative medicine have received unprecedented coverage by the media, fueling interest and enthusiasm in transplant clinicians and researchers. Regenerative medicine is changing the premise of solid organ transplantation, requiring transplantation investigators to become familiar with regenerative medicine investigations that can be extremely relevant to their work. Similarly, regenerative medicine investigators need to be aware of the needs of the transplant field to bring these two fields together for greater results. - Bridges the gap between regenerative medicine and solid organ transplantation and highlights reasons for collaboration - Explains the importance and future potential of regenerative medicine to the transplant community - Illustrates to regenerative medicine investigators the needs of the transplant discipline to drive and guide investigations in the most promising directions
Author : Andrea A. Zachary
Publisher : Humana
Page : 0 pages
File Size : 28,10 MB
Release : 2016-08-23
Category : Medical
ISBN : 9781493960156
After decades of research in clinical transplantation, new techniques have been developed that permit a further understanding of the immune mechanisms underlying immune recognition of allografts and a more accurate and thorough evaluation of compatibility between donors and recipients. The second edition of Transplantation Immunology: Methods and Protocols expands upon the previous edition with current, detailed methods in transplantation immunology. The new methods chapters cover four major areas that are being applied in compatibility evaluations and ongoing transplantation immunology research. Seven overview chapters provide reviews of the molecular basis for alloreactivity, current understanding of humoral and cellular mechanisms, as well as new developments in thoracic organ transplantation, composite tissue transplantation and in the transplantation of sensitized patients. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Transplantation Immunology: Methods and Protocol, Second Edition is devoted to transplantation immunology, both in the practice of compatibility testing and in transplantation research.
Author : Michele I. Morris
Publisher : Springer
Page : 0 pages
File Size : 13,34 MB
Release : 2021-06-22
Category : Medical
ISBN : 9783030258689
The field of transplant medicine has evolved significantly since the first kidney transplant was performed in 1954. Innovations in transplant immunosuppression have lowered the risk of organ rejection so that infectious complications are now the leading cause of hospitalization and mortality after solid organ transplant. Infection is also cited as the leading cause of non-relapse mortality after stem cell transplantation. As transplant centers have recognized the importance of transplant specific expertise in patient outcomes, the field of transplant infectious diseases has expanded into a recognized and highly valued subspecialty. International growth in solid organ and stem cell transplantation has outpaced access to such expertise, with some centers employing microbiology laboratory directors and transplant nephrologists as their lead infectious diseases consultants. This has been a particular challenge as the use of novel immunosuppressive regimens in new geographic and immigrant populations have fueled the emergence of new infection syndromes, with the initial presentation sometimes occurring in this most vulnerable patient population. This digital-first book is designed to meet the needs of practitioners engaged in transplant infectious disease practice who need more depth than they are able to find in UpToDate. It provides an overview of emerging infectious disease challenges with clinically relevant information regarding the epidemiology, diagnosis, management, and prevention of infections in solid organ and stem cell transplant recipients. Each chapter focuses on a clinical syndrome or pathogen with new or emerging implications for transplant patients. Given the rapidly evolving nature of emerging infections and topics in transplant infections, no resource has been published on these increasingly notorious issues; this this text is written by top, global experts who regularly update the material to ensure that readers will always have access to the most cutting edge material available. The editorial team consists of three experienced leaders in the field, all of whom have a strong record of scholarship and publication, as well as an international reputation. All three have focused their academic careers on emerging infectious diseases in transplantation, including a current and a past president of various infectious diseases and transplantation societies. The editors are also experienced reviewers and authors who have collaborated on multiple previous projects. All are committed to this project as a unique opportunity to make an important contribution to their field.
Author : Abdul Aziz Nather
Publisher : World Scientific Publishing Company
Page : 586 pages
File Size : 50,99 MB
Release : 2010-08-30
Category : Medical
ISBN : 9813107707
This book is written as a comprehensive guide for all tissue bank operators to procure and process bone and soft tissue allografts of highest quality standards for safe tissue transplantation practice in patients who require musculoskeletal tissue allograft transplantation. This comprehensive guide includes donor selection criteria, aseptic procurement techniques, laboratory testing and processing of grafts by deep freezing or freeze drying. It also includes sterilization of tissue grafts using gamma irradiation. Quality controls of tissue grafts are discussed in depth. The clinical transplantation of bone and soft tissue allografts is also discussed, with special consideration given to potential complications. Principles of sterile technique in the operating theater are described. The book also incorporates the basic sciences of tissue banking including anatomy, biomechanics, microbiology and immunology. It also covers radiation science so that the reader can better understand radiation sterilization of tissue grafts. Included in the book is a guide for public awareness programmes, radiation code of practice and general standards for tissue banking as recommended by the International Atomic Energy Agency.
Author : Faith Zor
Publisher : CRC Press
Page : 0 pages
File Size : 46,77 MB
Release : 2024-01-29
Category : Medical
ISBN : 9781032116761
This book summarizes rapid progress and innovation in transplantation and regenerative medicine - the merger of reconstructive plastic surgery and transplantation - called Vascularized Composite Allotransplantation. This merger includes a wide variety of previously impossible translplantations using grafts derived from organ donors.
Author : Gerard Doherty
Publisher : McGraw Hill Professional
Page : 1328 pages
File Size : 34,34 MB
Release : 2009-08-20
Category : Medical
ISBN : 0071635157
To-the-point information on more than 1000 diseases and disorders surgeons are most likely to encounter The leading single-source surgery book for house-staff, students, practitioners, and surgeons A Doody's Core Title for 2011! "This is an excellent source of updated, authoritative, and concise information on diseases encountered in general surgery and the surgical subspecialties of otolaryngology, urology, gynecology, orthopedics, plastic and reconstructive surgery, and pediatrics....This is a wonderful resource for all levels of surgical practitioners as well as nonsurgical practitioners. In my experience, it has provided me with a framework to prepare for both oral and written boards. 3 Stars."--Doody's Review Service Authoritative, concise, and completely up-to-date, CURRENT Diagnosis & Treatment Surgery features: Wide-ranging coverage that encompasses general surgery and all the important subspecialties including otolaryngology, urology, gynecology, orthopedics, plastic and reconstructive surgery, and pediatrics References linked to recent journal articles Logical quick-find organization made even more accessible by a comprehensive index More than 600 informative photographs and illustrations Detailed treatment algorithms NEW CD-ROM with content from Quick Answers: Surgery to speed diagnosis of symptoms and signs NEW Chapter on Training, Communication, Professionalism, and Systems-Based Practice Completely rewritten chapters on Wound Healing, Anesthesia, Otolaryngology/Head & Neck Surgery, The Heart, Neurosurgery, Gynecology, and Orthopedics
