True Alignment


Book Description

It cannot be overemphasized how important it is for leaders to ensure the company’s mission is manifested in the roles, expectations, and goals of every member of the organization. Companies live or die based on their ability to communicate and deliver on the promise their brand makes to its customers. But if that message is varied, or added to, or even unknown by a single member of the team, the resulting inefficiency, conflict, and disengagement will cripple a company’s ability to provide value to its customers. True Alignment reveals the blueprint for businesses of all types and sizes for creating a company culture where everyone is aligned to the vision and strategy behind the brand intention and responsible for living out the brand promise. You will learn how to: Decipher customer expectations Define the brand as a solution to the customer's needs Turn the unique selling proposition into the mission And much more You can replace the tires on a car, but if you don’t fix the alignment, you still won’t drive straight. The same goes for your company. Nothing else matters until the entire organization is aligned.




Authentic Alignment


Book Description

In Authentic Alignment: How Ancient Wisdom and Modern Science Can Revitalize Your Health, Happiness and Potential, Dr. Asha Prasad redirects our concept of health from the symptomatic to the foundational. True health is more than simply the absence of pain--it is nothing less than maximizing the hidden, almost limitless potential in each of us.




Radical Alignment


Book Description

Discover the Proven “Low Drama, High Joy” Method for Productive, Empathy-Based Communication and Collaboration. Why do so many organizations, teams, couples, families, and groups who should be working together end up wasting energy on unproductive conflict? Even when everyone has the same general goals, what’s often missing is a deeper alignment based on mutual trust, respect, and empathy. With Radical Alignment, top-level life and business coaches (and happily married couple) Alexandra Jamieson and Bob Gower share their potent method for helping groups to stop clashing and start working together—to jump from “we can’t” to an enthusiastic “hell yes!” The essential tool at the heart of Radical Alignment is the All-In Method: a four-step approach to communication designed to increase clarity, minimize miscommunication, honor each person’s individuality, and build a shared sense of trust and respect for long-term success. With easy-to-follow instruction, Jamieson and Gower bring you: • The Foundations of Great Communication—what works, what doesn’t, and how to analyze the strengths and weaknesses of your own style • The All-In Method—a step-by-step walk-through of this proven approach to getting into radical alignment with others • The Method in Action—examples and exercises for using the All-In Method at work, at home, and in any situation • Scripts, suggestions, guidance, and additional resources for making this a lifelong practice for greater connection and intimacy “We believe passionately that the world needs more aligned teams in our businesses, organizations, communities, families, and intimate partnerships,” write the authors. “This means we need people who are able to have powerful and clear exchanges that build better connections.” Radical Alignment brings you a “low drama, high joy” technique to transform the way you collaborate and communicate in every area of your life.




Sequence Alignment


Book Description

The sequencing of the human genome involved thousands of scientists but used relatively few tools. Obtaining sequences is simpler, but aligning the sequences remains a complicated but underappreciated aspect of comparative molecular biology. This book discusses the practice of alignment, and the procedures by which alignments are established.




The Alignment Problem: Machine Learning and Human Values


Book Description

A jaw-dropping exploration of everything that goes wrong when we build AI systems and the movement to fix them. Today’s “machine-learning” systems, trained by data, are so effective that we’ve invited them to see and hear for us—and to make decisions on our behalf. But alarm bells are ringing. Recent years have seen an eruption of concern as the field of machine learning advances. When the systems we attempt to teach will not, in the end, do what we want or what we expect, ethical and potentially existential risks emerge. Researchers call this the alignment problem. Systems cull résumés until, years later, we discover that they have inherent gender biases. Algorithms decide bail and parole—and appear to assess Black and White defendants differently. We can no longer assume that our mortgage application, or even our medical tests, will be seen by human eyes. And as autonomous vehicles share our streets, we are increasingly putting our lives in their hands. The mathematical and computational models driving these changes range in complexity from something that can fit on a spreadsheet to a complex system that might credibly be called “artificial intelligence.” They are steadily replacing both human judgment and explicitly programmed software. In best-selling author Brian Christian’s riveting account, we meet the alignment problem’s “first-responders,” and learn their ambitious plan to solve it before our hands are completely off the wheel. In a masterful blend of history and on-the ground reporting, Christian traces the explosive growth in the field of machine learning and surveys its current, sprawling frontier. Readers encounter a discipline finding its legs amid exhilarating and sometimes terrifying progress. Whether they—and we—succeed or fail in solving the alignment problem will be a defining human story. The Alignment Problem offers an unflinching reckoning with humanity’s biases and blind spots, our own unstated assumptions and often contradictory goals. A dazzlingly interdisciplinary work, it takes a hard look not only at our technology but at our culture—and finds a story by turns harrowing and hopeful.




Align


Book Description

USA Today and Wall Street Journal BestSellerAlign, part 1 of a 3-part series, shares four simple steps that transforms the way leaders lead and renew their self-confidence. Through the process Align offers, leaders develop the courage to connect with their team in a meaningful way and start winning together. Through Align, leaders will learn to create alignment within their organization and develop a culture built on employee fulfillment. It shows leaders exactly how to get there. Within Align, leaders learn how to: Foster a leadership style built on loving people Leverage their own natural gifts to become an effective leader Develop a culture built on employee fulfillment Create a company where everyone feels like their winning




POISED for Results


Book Description

POISED® for Results offers a comprehensive, effective, and efficient model for organizational leadership and individual and team growth and development. Navigating through each element of the POISED® process, with examples and stories from experience, and relatable historical stories and specific recommendations, POISED® for Results is designed to engage the reader and to provide an imminently usable structure for successful team engagement, strategy development and execution, and continuous growth. Dr. Scott’s expertise in leading, training, and guiding teams provides a seasoned educator’s perspective, and combines with Mark’s global business and organizational leadership experience to reach readers of all backgrounds and experiences. Newer leaders seeking a direction and seasoned leaders eager to finetune their skills of engaging teams with a proven and efficient process and model, will appreciate and be able to take away tools and processes and stimulate thinking for immediate application. The results of the POISED® model as explained in POISED® for Results will accrue in multiple dimensions: individual growth as a leader, a significant increase in team-member engagement by driving “optimal stress” for success and, ultimately, results that come from maximizing organization effectiveness in an efficient manner with focused leadership.




Bioinformatics and Functional Genomics


Book Description

The bestselling introduction to bioinformatics and genomics – now in its third edition Widely received in its previous editions, Bioinformatics and Functional Genomics offers the most broad-based introduction to this explosive new discipline. Now in a thoroughly updated and expanded third edition, it continues to be the go-to source for students and professionals involved in biomedical research. This book provides up-to-the-minute coverage of the fields of bioinformatics and genomics. Features new to this edition include: Extensive revisions and a slight reorder of chapters for a more effective organization A brand new chapter on next-generation sequencing An expanded companion website, also updated as and when new information becomes available Greater emphasis on a computational approach, with clear guidance of how software tools work and introductions to the use of command-line tools such as software for next-generation sequence analysis, the R programming language, and NCBI search utilities The book is complemented by lavish illustrations and more than 500 figures and tables - many newly-created for the third edition to enhance clarity and understanding. Each chapter includes learning objectives, a problem set, pitfalls section, boxes explaining key techniques and mathematics/statistics principles, a summary, recommended reading, and a list of freely available software. Readers may visit a related Web page for supplemental information such as PowerPoints and audiovisual files of lectures, and videocasts of how to perform many basic operations: www.wiley.com/go/pevsnerbioinformatics. Bioinformatics and Functional Genomics, Third Edition serves as an excellent single-source textbook for advanced undergraduate and beginning graduate-level courses in the biological sciences and computer sciences. It is also an indispensable resource for biologists in a broad variety of disciplines who use the tools of bioinformatics and genomics to study particular research problems; bioinformaticists and computer scientists who develop computer algorithms and databases; and medical researchers and clinicians who want to understand the genomic basis of viral, bacterial, parasitic, or other diseases.




Models and Algorithms for Genome Evolution


Book Description

This authoritative text/reference presents a review of the history, current status, and potential future directions of computational biology in molecular evolution. Gathering together the unique insights of an international selection of prestigious researchers, this must-read volume examines the latest developments in the field, the challenges that remain, and the new avenues emerging from the growing influx of sequence data. These viewpoints build upon the pioneering work of David Sankoff, one of the founding fathers of computational biology, and mark the 50th anniversary of his first scientific article. The broad spectrum of rich contributions in this essential collection will appeal to all computer scientists, mathematicians and biologists involved in comparative genomics, phylogenetics and related areas.




Pacific Symposium on Biocomputing 2008


Book Description

The Pacific Symposium on Biocomputing (PSB) 2008 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. Presentations are rigorously peer reviewed and are published in an archival proceedings volume. PSB 2008 will be held on January 4?8, 2008 at the Fairmont Orchid, Big Island of Hawaii. Tutorials will be offered prior to the start of the conference.PSB 2008 will bring together top researchers from the US, the Asian Pacific nations, and around the world to exchange research results and address open issues in all aspects of computational biology. It is a forum for the presentation of work in databases, algorithms, interfaces, visualization, modeling, and other computational methods, as applied to biological problems, with emphasis on applications in data-rich areas of molecular biology.The PSB has been designed to be responsive to the need for critical mass in sub-disciplines within biocomputing. For that reason, it is the only meeting whose sessions are defined dynamically each year in response to specific proposals. PSB sessions are organized by leaders of research in biocomputing's ?hot topics.? In this way, the meeting provides an early forum for serious examination of emerging methods and approaches in this rapidly changing field.