Element Analysis of Biological Samples


Book Description

Despite the development of innovative new analytical techniques for biological trace element research, today's trace element investigators face formidable obstacles to obtaining reliable data. This complete reference identifies and assesses the challenges the analyst encounters at each stage of an analysis, and discusses the effects of various techniques on the sample. Three internationally recognized scientists and authors consider the effects of the numerous collection, storage, and sample preparatory techniques used in sample analysis. Proper analytical quality control, including such critical factors as sampling and sample preparation, specimen preservation and storage, and ashing, is examined. The book also looks at sample preparation methods unique to various instruments and speciation chemistry issues, and examines the link between chemical analysis and specimen banking. A previously unrecognized source of error, presampling factors, is also discussed.




Elemental Analysis of Biological Systems


Book Description

The purpose of this volume is to emphasize the fact that biological trace element research is a multidisciplinary science which requires a prudent combination of biological insight and analytical awareness. The text frequently stresses that accurate measurements on biologically and analytically "valid" samples hold the key for success in future investigations. It reminds the analytical scientists and the life sciences researchers that their perceptions should extend beyond conventional limits - namely, the former as generators of data and the latter as interpreters of those findings. This book enables the reader to understand the intricacies of elemental composition studies in biological systems, and also provides a valuable source of information to biologists, biochemists, physicians, nutritionists and related scientific workers who intend to draw meaningful conclusions from the analytical findings.




TRAC: Trends in Analytical Chemistry


Book Description

Trends in Analytical Chemistry, Volume 5 focuses on the advancements of processes, technologies, automation, and applications of analytical chemistry. The selection first offers information on graphics programming for the IBM PC using FORTRAN, PASCAL, and C, including graphics hardware system software, assembly language routines, and high level interface. The text then elaborates on the place of affinity chromatography in the production and purification of biomolecules from cultured cells and zone electrophoresis in open-tubular capillaries. Discussions focus on column and instrument design, applications, affinity chromatography in protein production from cells, and economic aspects of production and purification of proteins from cell cultures. The manuscript takes a look at polarographic and voltammetric techniques and their application to the determination of vitamins and coenzymes and activation analysis with charged particles. Topics include accelerators, principle of charged particle activation analysis, and applications. The text then examines the development of microbiological and immunological assays for antibiotics and the use of computer system for a small analytical research laboratory. The book is a dependable reference for readers interested in the trends in analytical chemistry.













Advances in Chromatography


Book Description

This book provides up-to-date information on a wide range of developments in chromatographic methods and applications. It also presents timely, cutting-edge reviews in the fields of bio-, analytical, organic, polymer, and pharmaceutical chemistry.







High-Throughput Analysis for Food Safety


Book Description

HIGH THROUGHPUT ANALYSIS FOR FOOD SAFETY MEETS FSMA REQUIREMENTS WITH THE LATEST ADVANCES IN HIGH-THROUGHPUT SCREENING High-Throughput Analysis for Food Safety addresses the fundamental concepts involved in the rapid screening for contaminants, including residual veterinary drugs, proteins, metals, hormones, pesticides, and adulterants. Addressing the need for—and requirements of—rapid screening tests, the book includes discussions of regulations and compliance issues from perspectives of both domestic and global industry and government contributors. The latest developments and most common techniques are focused on, with an emphasis on the applicability of both stand-alone mass spectrometry methods and coupled techniques. Beginning with a review of high-throughput analysis basics, the authors conduct a full exploration of mass spectrometry applications allowing readers to: Survey GC-MS, LC-MS, stand-alone MS, and tandem MS methods in foodanalysis and contaminant screening Review quality control standards, method validation, and ongoing analyticalcontrol Examine the current methods used to detect veterinary medicinal productresidues in food, as well as future directionsRecent Recent incidents around the globe have turned the food industry toward high-throughput analysis, and the Food Safety Modernization Act has made it a legal requirement in the US. This resource provides an in-depth discussion of the latest advances in methods and instrumentation.




Analytical Techniques in Biosciences


Book Description

Analytical Techniques in Biosciences: From Basics to Applications presents comprehensive and up-to-date information on the various analytical techniques obtainable in bioscience research laboratories across the world. This book contains chapters that discuss the basic bioanalytical protocols and sample preparation guidelines. Commonly encountered analytical techniques, their working principles, and applications were presented. Techniques, considered in this book, include centrifugation techniques, electrophoretic techniques, chromatography, titrimetry, spectrometry, and hyphenated techniques. Subsequent chapters emphasize molecular weight determination and electroanalytical techniques, biosensors, and enzyme assay protocols. Other chapters detail microbial techniques, statistical methods, computational modeling, and immunology and immunochemistry.The book draws from experts from key institutions around the globe, who have simplified the chapters in a way that will be useful to early-stage researchers as well as advanced scientists. It is also carefully structured and integrated sequentially to aid flow, consistency, and continuity. This is a must-have reference for graduate students and researchers in the field of biosciences. - Presents basic analytical protocols and sample-preparation guidelines - Details the various analytical techniques, including centrifugation, spectrometry, chromatography, and titrimetry - Describes advanced techniques such as hyphenated techniques, electroanalytical techniques, and the application of biosensors in biomedical research - Presents biostatistical tools and methods and basic computational models in biosciences