Ultradian Rhythms from Molecules to Mind


Book Description

5. 1. 1 Biological Rhythms and Clocks From an evolutionary perspective, the adaptation of an organism’s behavior to its environment has depended on one of life’s fundamental traits: biological rhythm generation. In virtually all light-sensitive organisms from cyanobacteria to humans, biological clocks adapt cyclic physiology to geophysical time with time-keeping properties in the circadian (24 h), ultradian (24 h) domains (Edmunds, 1988; Lloyd, 1998; Lloyd et al. , 2001; Lloyd and Murray, 2006; Lloyd, 2007; Pittendrigh, 1993; Sweeney and Hastings, 1960) By definition, all rhythms exhibit regular periodicities since they constitute a mechanism of timing. Timing exerted by oscillatory mechanisms are found throughout the biological world and their periods span a wide range from milliseconds, as in the action potential of n- rons and the myocytes, to the slow evolutionary changes that require thousands of generations. In this context, to understand the synchronization of a population of coupled oscillators is an important problem for the dynamics of physiology in living systems (Aon et al. , 2007a, b; Kuramoto, 1984; Strogatz, 2003; Winfree, 1967). Circadian rhythms, the most intensively studied, are devoted to measuring daily 24 h cycles. A variety of physiological processes in a wide range of eukaryotic organisms display circadian rhythmicity which is characterized by the following major properties (Anderson et al. , 1985; Edmunds, 1988): (i) stable, autonomous (self-sustaining) oscillations having a free-running period under constant envir- mental conditions of ca.




Rhythms of the Brain


Book Description

Studies of mechanisms in the brain that allow complicated things to happen in a coordinated fashion have produced some of the most spectacular discoveries in neuroscience. This book provides eloquent support for the idea that spontaneous neuron activity, far from being mere noise, is actually the source of our cognitive abilities. It takes a fresh look at the coevolution of structure and function in the mammalian brain, illustrating how self-emerged oscillatory timing is the brain's fundamental organizer of neuronal information. The small-world-like connectivity of the cerebral cortex allows for global computation on multiple spatial and temporal scales. The perpetual interactions among the multiple network oscillators keep cortical systems in a highly sensitive "metastable" state and provide energy-efficient synchronizing mechanisms via weak links. In a sequence of "cycles," György Buzsáki guides the reader from the physics of oscillations through neuronal assembly organization to complex cognitive processing and memory storage. His clear, fluid writing-accessible to any reader with some scientific knowledge-is supplemented by extensive footnotes and references that make it just as gratifying and instructive a read for the specialist. The coherent view of a single author who has been at the forefront of research in this exciting field, this volume is essential reading for anyone interested in our rapidly evolving understanding of the brain.




Restoring the Brain


Book Description

Restoring the Brain: Neurofeedback as an Integrative Approach describes the history and process by which neurofeedback has become an effective tool for treating many mental and behavioral health conditions. It explains how new brain research and improvements in imaging technology allow for a new conceptualization of the brain. It also discusses how biomedical factors can degrade brain functioning and cause a wide range of symptoms of mental disorders. The book is written in an accessible style for easy understanding and application to classification and treatment. It shares the clinical experiences of practitioners working with specific symptom constellations generally categorized by a DSM diagnostic label. It examines the brain as a self-regulating communications system and discusses how much of mental dysfunction can be understood as acquired brain behavior that can be redirected with the help of EEG-based neurofeedback. It describes principles and practices of integrating neurofeedback that make redirection possible. Recent discoveries on the neuroelectrical properties of the brain illuminate the possibilities of combining innovative neurotherapy techniques with integrative medicine to achieve optimal brain function. Case studies of clinical applications highlight the effectiveness of neurofeedback in treating autism, ADHD, and trauma, particularly PTSD. Integrative approaches are the future of health care, and neurofeedback will play an increasingly significant role. Restoring the Brain: Neurofeedback as an Integrative Approach gives you a better understanding of the use and practice of neurofeedback.




Ultradian Rhythms in Life Processes


Book Description

Profound progress has been made in the fields of chronobiology and psychobiology within the past decade, in theory, experiment and clinical application. This volume integrates these new developments on all levels from the molecular, genetic and cellular to the psycho social processes of everyday life. We present a balanced variety of research from workers around the globe, who discuss the funda mental significance of their approach for a new understanding of the central role of ultradian rhythms in the self-organizing and adaptive dynamics of all life processes. The years since the publication of Ultra dian rhythms in physiology and behavior by Schultz and Lavie in 1985 have seen a burgeoning realization of the ubiquity and importance of ultradian rhythms within and between every level of the psychobiological hierarchy. The experimental evidence lies scattered through a disparate litera ture, and this volume attempts, albeit in a highly selective manner, to bring together some of the different strands. The editors are very conscious of the omission of many important current aspects; e.g. we have not included any of the fascinating and indeed long and well-established experiments with plants (Bunning 1971, 1977; Guillaume and Koukkari 1987; Millet et al. 1988; 10hnsson et al. 1990) that are widely regarded as having initiated the whole field of chronobiology (De Mairan 1729). Neither have we reviewed recent developments on glycolytic oscillations, since a great deal of the seminal work was already completed by 1973 (Chance et al. 1973).




Aspects of Pacemakers


Book Description

Outstanding steps forward were made in the last decades in terms of identification of endogenous pacemakers and the exploration of their controllability. New "artifical" devices were developed and are now able to do much more than solely pacemaking of the heart. In this book different aspects of pacemaker - functions and interactions, in various organ systems were examined. In addition, various areas of application and the potential side effects and complications of the devices were discussed.




Happiness, Healing, Enhancement


Book Description

Praise for Happiness, Healing, Enhancement "Filled with good strategies based in research, compelling case material, and most importantly, practical advice, this book belongs in the library of everyone interested in what it means to live well. It provides not only ample food for thought, but for action." —Christopher Peterson, Professor of Psychology, University of Michigan "If you are a therapist, a coach—or if you want to help yourself and others flourish—then this book is a must-read. It is an important theoretical and practical contribution to the field of positive psychology—and, in fact, to the field of psychology as a whole." —Tal Ben-Shahar, author of Happier and The Pursuit of Perfect A practical guide to applying the principles of positive psychology in your mental health practice Edited by internationally recognized psychologist, author, and therapist trainer George Burns, Happiness, Healing, Enhancement: Your Casebook Collection for Applying Positive Psychology in Therapy provides thought-provoking yet realistic and practical contributions from practitioners of positive psychology from around the world who share how they have translated solid, positive psychology research into sound clinical practice. Organized to make searching for a particular diagnostic category or therapeutic outcome fast and easy, this guide features: Contributions from some of the world's foremost positive psychology clinicians, researchers, and teachers, including P. Alex Linley, Betty Alice Erickson, Robert Weis, Antonella Delle Fave, Richard G. Tedeschi, Robert Biswas-Diener, Michael D. Yapko, and Bill O'Hanlon Examples and strategies including a "Putting It into Practice" feature that illustrates how readers can immediately apply the therapeutic applications covered in each chapter Building on the proven benefits of the positive psychology movement, Happiness, Healing, Enhancement will teach you new skills that will strengthen your practice of therapy and equip your clients with the pathways to overcome challenging problems and live a full, satisfying life.




Intrinsic Clocks


Book Description

"Intrinsic Clocks" presents an array of current research activities on intrinsic clocks and their contributions to biology and physiology. It elucidates the current models for the intrinsic clocks, their molecular components and key mechanisms as well as the key brain regions and animal models for their behavioral analysis. It provides a timely view on how these clocks guide behavior, and how their disruption may cause depressive-like behavior and impairment in cognitive functions. Thereby, any specific method by which the mood-related functions of the intrinsic clocks might be influenced bears therapeutic potential and has clinical interest. The importance of some of these mechanisms was highlighted by the 2017 award of the Nobel Prize in Physiology or Medicine to Jeffrey C. Hall, Michael Rosbash, and Michael W. Young for their discoveries of the genetic control of the daily biological rhythm. The key to the explanation was the discovery of transcription-translation feedback loops of the so-called “clock genes.”




Introduction To Metabolic And Cellular Engineering, An (Second Edition)


Book Description

Metabolic and Cellular Engineering (MCE) is more than an exciting scientific enterprise. It has become the cornerstone for coping with the challenges ahead of mankind. Continuous developments, new concepts, and technological innovations will enable us to deal with emerging challenges, and solve problems once thought impossible ten years ago. Challenges in MCE are broad- from unraveling fundamental aspects of cellular function to meeting unsatiated energy and food demands that are rising in parallel with population growth.In charting the progress of MCE during the last decade, we could not help but feel in awe of the enormous strides of progress made from the nascent Metabolic Engineering to the Systems Bioengineering of today. The burgeoning availability of genomic sequences from diverse species has been spectacular. It has become the engine that drives the genetic means for the modification of existing organisms and the generation of synthetic, man-made ones. From the initial attempts at purposeful genetic modification of a cell for the production of valuable compounds, we have now moved on to changing microbes genetically or metabolically.The arsenal of experimental and theoretical tools available for Metabolic and Cellular Engineering has expanded enormously, driven by the re-emergence of Physiology as Systems Biology. The revival of the concept of networks fueled by new developments has become central to Systems Biology. Networks represent an integrative vision of how processes of disparate nature relate to each other, and as such is becoming a key analytical and conceptual tool for MCE. This book reflects and addresses all these ongoing changes while providing the essential conceptual and analytical tools needed to understand and work in the MCE research field.




Rhythms in Plants


Book Description

This second edition of a well-received book focuses on rhythmic behaviour in plants, which regulates all developmental and adaptive responses and can thus be regarded as quintessential to life itself. The chapters provide a timely update on recent advances in this field and comprehensively summarize the current state of knowledge concerning the molecular and physiological mechanisms behind circadian and ultradian oscillations in plants, their physiological implications for growth and development and adaptive responses to a dynamic environment. Written by a diverse group of leading researchers, the book will spark the interest of readers from many branches of science: from physicists and chemists wishing to learn about the multi-faceted rhythms in plants, to biologists and ecologists involved in the state-of-the-art modelling of complex rhythmic phenomena.




The Practitioner's Guide to Mirroring Hands


Book Description

Richard Hill and Ernest L. Rossi's The Practitioner's Guide to Mirroring Hands: A Client-Responsive Therapy that Facilitates Natural Problem-Solving and Mind Body Healing describes in detail how Mirroring Hands is conducted, and explores the framework of knowledge and understanding that surrounds and supports its therapeutic process. Foreword by Jeffrey K. Zeig, Ph.D. In this instructive and illuminating manual, Hill and Rossi show you how Mirroring Hands enables clients to unlock their problem-solving and mind body healing capacities to arrive at a resolution in a way that many other therapies might not. The authors offer expert guidance as to its client-responsive applications and differentiate seven variations of the technique in order to give the practitioner confidence and comfort in their ability to work within and around the possibilities presented while in session. Furthermore, Hill and Rossi punctuate their description of how Mirroring Hands is conducted with a range of illustrative casebook examples and stage-by-stage snapshots of the therapy in action: providing scripted language prompts and images of a client's hand movement that demonstrate the processes behind the technique as it takes the client from disruption into the therapeutic; and from there to integration, resolution, and a state of well-being. This book begins by tracing the emergence of the Mirroring Hands approach from its origins in Rossi's studies and experiences with Milton H. Erickson and by presenting a transcription of an insightful discussion between Rossi and Hill as they challenge some of the established ways in which we approach psychotherapy, health, and well-being. Building upon this exchange of ideas, the authors define and demystify the nature of complex, non-linear systems and skillfully unpack the three key elements of induction to therapeutic consciousness focused attention, curiosity, and nascent confidence in a section dedicated to preparing the client for therapy. Hill and Rossi supply guidance for the therapist through explanation of therapeutic dialogue's non-directive language principles, and through exploration of the four-stage cycle that facilitates the client's capacity to access their natural problem-solving and mind body healing. The advocate Mirroring Hands as not only a therapeutic technique, but also for all practitioners engaged in solution-focused therapy. Through its enquiry into the vital elements of client-cue observation, symptom-scaling, and rapport-building inherent in the therapist/client relationship, this book shares great wisdom and insight that will help the practitioner become more attuned to their clients' inner worlds and communication patterns. Hill and Rossi draw on a wealth of up-to-date neuroscientific research and academic theory to help bridge the gap between therapy's intended outcomes and its measured neurological effects, and, towards the book's close, also open the door to the study of quantum field theory to inspire the reader's curiosity in this fascinating topic. An ideal progression for those engaged in mindfulness and meditation, this book is the first book on the subject specially written for all mental health practitioners and is suitable for students of counseling, psychotherapy, psychology, and hypnotherapy, as well as anyone in professional practice.