Uncertainty propagation and importance measure assessment


Book Description

The authors investigate the effects that different representations of epistemic uncertainty have on practical risk assessment problems. Two different application problems are considered: 1. the estimation of component importance measures in the presence of epistemic uncertainties; 2. the propagation of uncertainties through a risk flooding model. The focus is on the epistemic uncertainty affecting the parameters of the models that describe the components’ failures due to incomplete knowledge of their values. This epistemic uncertainty is represented using probability distributions when sufficient data is available for statistical analysis, and by possibility distributions when the information available to define the parameters’ values comes from experts, in the form of imprecise quantitative statements or judgments. Three case studies of increasing complexity are presented:  a pedagogical example of importance measure assessment on a three-component system from the literature;  assessment of importance measures for the auxiliary feed water system of a nuclear pressurized water reactor;  an application in environmental modelling, with an analysis of uncertainty propagation in a hydraulic model for the risk-based design of a flood protection dike.




Literature review of methods for representing uncertainty


Book Description

This document provides a critical review of different frameworks for uncertainty analysis, in a risk analysis context : classical probabilistic analysis, imprecise probability (interval analysis), probability bound analysis, evidence theory, and possibility theory. The driver of the critical analysis is the decision-making process and the need to feed it with representative information derived from the risk assessment, to robustly support the decision. Technical details of the different frameworks are exposed only to the extent necessary to analyze and judge how these contribute to the communication of risk and the representation of the associated uncertainties to decision-makers, in the typical settings of high-consequence risk analysis of complex systems with limited knowledge on their behaviour.




Science and Judgment in Risk Assessment


Book Description

The public depends on competent risk assessment from the federal government and the scientific community to grapple with the threat of pollution. When risk reports turn out to be overblownâ€"or when risks are overlookedâ€"public skepticism abounds. This comprehensive and readable book explores how the U.S. Environmental Protection Agency (EPA) can improve its risk assessment practices, with a focus on implementation of the 1990 Clean Air Act Amendments. With a wealth of detailed information, pertinent examples, and revealing analysis, the volume explores the "default option" and other basic concepts. It offers two views of EPA operations: The first examines how EPA currently assesses exposure to hazardous air pollutants, evaluates the toxicity of a substance, and characterizes the risk to the public. The second, more holistic, view explores how EPA can improve in several critical areas of risk assessment by focusing on cross-cutting themes and incorporating more scientific judgment. This comprehensive volume will be important to the EPA and other agencies, risk managers, environmental advocates, scientists, faculty, students, and concerned individuals.




Particle Image Velocimetry


Book Description

Particle image velocimetry, or PIV, refers to a class of methods used in experimental fluid mechanics to determine instantaneous fields of the vector velocity by measuring the displacements of numerous fine particles that accurately follow the motion of the fluid. Although the concept of measuring particle displacements is simple in essence, the factors that need to be addressed to design and implement PIV systems that achieve reliable, accurate, and fast measurements and to interpret the results are surprisingly numerous. The aim of this book is to analyze and explain them comprehensively.




Data and Error Analysis


Book Description

For the lab/experimentation course in physics depts. and/or any course in physics, chemistry, geology, etc. with a lab component focusing on data and error analysis. Designed to help science students process data without lengthy and boring computations, this text/disk package provides useful algorithms and programs that allow students to do analysis more quickly than was previously possible. Using a "learn by doing" approach, it provides simple, handy rules for handling data and estimating errors both by graphical and analytic methods without long discussions and involved theoretical derivations.




Nutritional Care of the Patient with Gastrointestinal Disease


Book Description

This evidence-based book serves as a clinical manual as well as a reference guide for the diagnosis and management of common nutritional issues in relation to gastrointestinal disease. Chapters cover nutrition assessment; macro- and micronutrient absorption; malabsorption; food allergies; prebiotics and dietary fiber; probiotics and intestinal microflora; nutrition and GI cancer; nutritional management of reflux; nutrition in IBS and IBD; nutrition in acute and chronic pancreatitis; enteral nutrition; parenteral nutrition; medical and endoscopic therapy of obesity; surgical therapy of obesity; pharmacologic nutrition, and nutritional counseling.




Quantitative Environmental Risk Analysis for Human Health


Book Description

QUANTITATIVE ENVIRONMENTAL RISK ANALYSIS FOR HUMAN HEALTH An updated edition of the foundational guide to environmental risk analysis Environmental risk analysis is a systematic process essential for the evaluation, management, and communication of the human health risk posed by the release of contaminants to the environment. Performed correctly, risk analysis is an essential tool in the protection of the public from the health hazards posed by chemical and radioactive contaminants. Cultivating the quantitative skills required to perform risk analysis competently is a critical need. Quantitative Environmental Risk Analysis for Human Health meets this need with a thorough, comprehensive coverage of the fundamental knowledge necessary to assess environmental impacts on human health. It introduces readers to a robust methodology for analyzing environmental risk, as well as to the fundamental principles of uncertainty analysis and the pertinent environmental regulations. Now updated to reflect the latest research and new cutting-edge methodologies, this is an essential contribution to the practice of environmental risk analysis. Readers of the second edition of Quantitative Environmental Risk Analysis for Human Health will also find: Detailed treatment of source and release characterization, contaminant migration, exposure assessment, and more New coverage of computer-based analytical methods A new chapter of case studies providing actual, real-world examples of environmental risk assessments Quantitative Environmental Risk Analysis for Human Health is must-have for graduate and advanced undergraduate students in civil engineering, environmental engineering, and environmental science, as well as for risk analysis practitioners in industry, environmental consultants, and regulators.




Data Uncertainty and Important Measures


Book Description

The first part of the book defines the concept of uncertainties and the mathematical frameworks that will be used for uncertainty modeling. The application to system reliability assessment illustrates the concept. In the second part, evidential networks as a new tool to model uncertainty in reliability and risk analysis is proposed and described. Then it is applied on SIS performance assessment and in risk analysis of a heat sink. In the third part, Bayesian and evidential networks are used to deal with important measures evaluation in the context of uncertainties.







Science and Decisions


Book Description

Risk assessment has become a dominant public policy tool for making choices, based on limited resources, to protect public health and the environment. It has been instrumental to the mission of the U.S. Environmental Protection Agency (EPA) as well as other federal agencies in evaluating public health concerns, informing regulatory and technological decisions, prioritizing research needs and funding, and in developing approaches for cost-benefit analysis. However, risk assessment is at a crossroads. Despite advances in the field, risk assessment faces a number of significant challenges including lengthy delays in making complex decisions; lack of data leading to significant uncertainty in risk assessments; and many chemicals in the marketplace that have not been evaluated and emerging agents requiring assessment. Science and Decisions makes practical scientific and technical recommendations to address these challenges. This book is a complement to the widely used 1983 National Academies book, Risk Assessment in the Federal Government (also known as the Red Book). The earlier book established a framework for the concepts and conduct of risk assessment that has been adopted by numerous expert committees, regulatory agencies, and public health institutions. The new book embeds these concepts within a broader framework for risk-based decision-making. Together, these are essential references for those working in the regulatory and public health fields.