Isotopic Analysis


Book Description

Edited by two very well-known and respected scientists in the field, this excellent practical guide is the first to cover the fundamentals and a wide range of applications, as well as showing readers how to efficiently use this increasingly important technique. From the contents: * The Isotopic Composition of the Elements * Single-Collector ICP-MS * Multi-Collector ICP-MS * Advances in Laser Ablation - Multi-Collector ICP-MS * Correction for Instrumental Mass Discrimination in Isotope Ratio Determination with Multi-Collector ICP-MS * Reference Materials in Isotopic Analysis * Quality Control in Isotope Ratio Applications * Determination of Trace Elements and Elemental Species Using Isotope Dilution ICP-MS * Geochronological Dating * Application of Multi-Collector ICP-MS to Isotopic Analysis in Cosmochemistry * Establishing the Basis for Using Stable Isotope Ratios of Metals as Paleoredox Proxies * Isotopes as Tracers of Elements Across the Geosphere-Biosphere Interface * Archaeometric Applications * Forensics Applications * Nuclear Applications * The Use of Stable Isotope Techniques for Studying Mineral and Trace Element Metabolism in Humans * Isotopic Analysis via Multi-Collector ICP-MS in Elemental Speciation A must-have for newcomers as well as established scientists seeking an overview of isotopic analysis via ICP-MS.




Metallomics


Book Description

This book focuses on recent topics in metallomics, a study of the metallome, or metal-containing biomolecules. Metals can induce various physiological and toxicological effects in a very small amounts, in other words, the concentrations of biometals are very low in organisms. Thus, analytical techniques for a trace amount of metal are crucial to understand the biological and toxicological functions of metals.This volume begins with an overview of metallomics including the history and development of the field. Subsequent parts provide basic and advanced techniques for metallomics. Speciation and imaging of metals are basic approaches to reveal the function of the metallome. The applications of speciation using an HPLC hyphenated with inductively coupled plasma mass spectrometry (LC-ICP-MS) and flow cytometry ICP-MS are described. As advanced approaches, the applications using a micro-flow injection-ICP-MS, an ICP-triple quadrupole mass spectrometer, an ICP-sector field mass spectrometer, and an ICP-multi-collector mass spectrometer are mentioned. For the imaging of metals, basic principles and applications of several techniques such as scanning X-ray fluorescence microscopy and ICP-MS equipped with laser ablation (LA-ICP-MS) are presented. Speciation analyses using electrospray ionization mass spectrometry (ESI-MS), X-ray Absorption Spectroscopy (XAS), and nuclear magnetic resonance spectroscopy (NMR) are also introduced. The last part highlights the medical and pharmaceutical applications of metallomics. Molecular biological approaches to reveal the effects of toxic metals, metal functions in brain and neurodegenerative diseases, and metallodrugs are explained. The topic of metal transporters is also presented.




Handbook of Stable Isotope Analytical Techniques Vol II


Book Description

This two-volume reference serves as a handbook containing a wealth of information for all isotope chemists working in a wide range of disciplines including anthropology to ecology; drug detection methodology to toxicology; nutrition to food science; and the atmospheric sciences to geochemistry.Complementing the first volume, Volume II includes matters that are not strictly confined to the analytical techniques themselves, but relate to analysis of stable isotopes, such as the views on the development of mass spectrometers, isotopic scales, standards and references, and directives for setting up a laboratory.ALSO AVAILABLE:Volume I: Dec. 2004, 0444511148/9780444511140, $176.00Volume I and II (set): Oct. 2007, 0444511164/9780444511164, $205.00 Presents an encyclopedic overview of stable isotope analytical techniques in an objective way Includes descriptions of methods and diagrams of analytical devices Addresses how older techniques formed the basis for present-day techniques, which can be useful in constructing modern analytical systems Completments Volume I of the set




Iron Geochemistry: An Isotopic Perspective


Book Description

This book provides a comprehensive summary of research to date in the field of stable iron isotope geochemistry. Since research began in this field 20 years ago, the field has grown to become one of the major research fields in "non-traditional" stable isotope geochemistry. This book reviews all aspects of the field, from low-temperature to high-temperature processes, biological processes, and cosmochemical processes. It provides a detailed history and state-of-the art summary about analytical methods to determine Fe-isotope ratios and discusses analytical and sample prospects.




The Oxford Handbook of the Archaeology of Diet


Book Description

Humans are unique among animals for the wide diversity of foods and food preparation techniques that are intertwined with regional cultural distinctions around the world. The Oxford Handbook of the Archaeology of Diet explores evidence for human diet from our earliest ancestors through the dispersal of our species across the globe. As populations expanded, people encountered new plants and animals and learned how to exploit them for food and other resources. Today, globalization aside, the results manifest in a wide array of traditional cuisines based on locally available indigenous and domesticated plants and animals. How did this complexity emerge? When did early hominins actively incorporate animal foods into their diets, and later, exploit marine and freshwater resources? What were the effects of reliance on domesticated grains such as maize and rice on past populations and the health of individuals? How did a domesticated plant like maize move from its place of origin to the northernmost regions where it can be grown? Importantly, how do we discover this information, and what can be deduced about human health, biology, and cultural practices in the past and present? Such questions are explored in thirty-three chapters written by leading researchers in the study of human dietary adaptations. The approaches encompass everything from information gleaned from comparisons with our nearest primate relatives, tools used in procuring and preparing foods, skeletal remains, chemical or genetic indicators of diet and genetic variation, and modern or historical ethnographic observations. Examples are drawn from across the globe and information on the research methods used is embedded within each chapter. The Handbook provides a comprehensive reference work for advanced undergraduate and graduate students and for professionals seeking authoritative essays on specific topics about diet in the human past.




Non-Traditional Stable Isotopes


Book Description

The development of multi-collector inductively coupled plasma mass spectrometry (MC-ICPMS) makes it possible to precisely measure non-traditional stable isotopes. This volume reviews the current status of non-traditional isotope geochemistry from analytical, theoretical, and experimental approaches to analysis of natural samples. In particular, important applications to cosmochemistry, high-temperature geochemistry, low-temperature geochemistry, and geobiology are discussed. This volume provides the most comprehensive review on non-traditional isotope geochemistry for students and researchers who are interested in both the theory and applications of non-traditional stable isotope geochemistry.




Iron Isotopes


Book Description

There are no books published on this subject yet. Only review articles and review book chapters have been written so far. Perhaps the most comprehensive ones were published in 2004 in the Reviews in Geochemistry and Cosmochemistry series under the title "Geochemistry of non-traditional isotopes". Brian Beard and Clark Johnson wrote two chapters devoted to Fe isotopes. However, because the target was the specialist audience and this field expands so rapidly, this book is already partly outdated.




Assessment of Iron Bioavailability in Humans Using Stable Iron Isotope Techniques


Book Description

This publication on the assessment of iron bioavailability was developed as part of the IAEAs continuing efforts to transfer knowledge and technology in the use of stable isotope techniques in nutrition. It provides information on the theoretical background and practical application of state of the art methodology to measure human iron absorption and dietary iron bioavailability using stable (non-radioactive) isotopes. These techniques can be used to guide fortification and food based strategies to combat iron deficiency, which remains unacceptably high among infants, children and women of childbearing age in developing countries.




Geochemistry


Book Description

This book aims to explore basic principles, concepts and applications of geochemistry. Topics include chemical weathering, impacts on living beings and water, geochemical cycles, oxidation and redox reactions in geochemistry, isotopes, analytical techniques, medicinal, inorganic, marine, atmospheric, and environmental applications, as well as case studies. This book helps in understanding the chemical composition of the earth and its applications. It also includes beneficial effects, bottlenecks, solutions, and future directions in geochemistry.