Various Antidotes


Book Description

"A greatly gifted and highly original artist...Various Antidotes is purely and simply wonderful."--The New York Times Book Review The miraculous, transformative stories of Joanna Scott's Various Antidotes range across the world of history and science, alighting on figures both real and imaginary. The stories within are those of obsession and brilliance, of the ultimately human recognition that the world is larger than we believe it to be and that we, as figures within it, have through understanding the power to change that world. Whether through learning or madness or accident, the scientists and students within Various Antidotes expose us to the glorious blossom of the natural world.




Antidotes to Toxins and Drugs


Book Description

Antidotes to Toxins and Drugs: From Natural Sources to Drug Discovery in Toxicology presents recent advances in the discovery of natural antidotes to toxins, drug intoxications and overdoses in pharmacology, drug discovery and toxicology. The text provides detailed information about toxins and their natural antidotes, along with the identification and screening of antidotes for drug intoxications and overdoses. Written by a global team of experts, it describes the potential uses of natural products in toxicology and their applications in medicine and in the pharmaceutical sciences. This book will be a key resource for drug developers, medicinal chemists and toxicologists, among others.Sections shine a particular focus on mechanisms of action, various principles in pharmacokinetics and pharmacodynamics terms, and possible sources and synthesis techniques for these phytochemicals. - Details recent advances in the discovery of natural antidotes from medicinal plants and phytochemicals - Includes advances in the discovery of antidotes to drug intoxications and overdoses - Describes modern screening assays for toxins and drug intoxications - Features information on recent advances in toxicology




Antidotes


Book Description

Antidotes provides up-to-date information on the development and clinical use of antidotes, their proposed mechanism of action, toxicity, availability and practical aspects of their clinical use. The antidotes discussed are primarily those either in current use, or under consideration or development. Some other compounds of mainly historical intere




The Antidote


Book Description

Self-help books don't seem to work. Few of the many advantages of modern life seem capable of lifting our collective mood. Wealth—even if you can get it—doesn't necessarily lead to happiness. Romance, family life, and work often bring as much stress as joy. We can't even agree on what "happiness" means. So are we engaged in a futile pursuit? Or are we just going about it the wrong way? Looking both east and west, in bulletins from the past and from far afield, Oliver Burkeman introduces us to an unusual group of people who share a single, surprising way of thinking about life. Whether experimental psychologists, terrorism experts, Buddhists, hardheaded business consultants, Greek philosophers, or modern-day gurus, they argue that in our personal lives, and in society at large, it's our constant effort to be happy that is making us miserable. And that there is an alternative path to happiness and success that involves embracing failure, pessimism, insecurity, and uncertainty—the very things we spend our lives trying to avoid. Thought-provoking, counterintuitive, and ultimately uplifting, The Antidote is the intelligent person's guide to understanding the much-misunderstood idea of happiness.




Toxicology Pearls


Book Description

This new book uses the unique vignette format of the Pearls Series" to explore a variety of issues that arise in the everyday practice of toxicology. The authors present individual case scenarios, physical findings, lab data, and clinical photographs of actual cases and challenge readers to formulate a diagnosis and treatment strategy based on the information provided. The correct diagnosis and a discussion of the findings follow each case presentation. Offers actual case studies in toxicology that challenge readers to formulate their own diagnoses. Reveals the actual diagnosis for each case with discussions of the relevant disorders. Distills 3-4 clinical pearls for each case-helping readers to avoid complications and achieve optimal outcomes and pitfalls. Uses illustrations to emphasize important points.




Chemical and Biological Terrorism


Book Description

The threat of domestic terrorism today looms larger than ever. Bombings at the World Trade Center and Oklahoma City's Federal Building, as well as nerve gas attacks in Japan, have made it tragically obvious that American civilians must be ready for terrorist attacks. What do we need to know to help emergency and medical personnel prepare for these attacks? Chemical and Biological Terrorism identifies the R&D efforts needed to implement recommendations in key areas: pre-incident intelligence, detection and identification of chemical and biological agents, protective clothing and equipment, early recognition that a population has been covertly exposed to a pathogen, mass casualty decontamination and triage, use of vaccines and pharmaceuticals, and the psychological effects of terror. Specific objectives for computer software development are also identified. The book addresses the differences between a biological and chemical attack, the distinct challenges to the military and civilian medical communities, and other broader issues. This book will be of critical interest to anyone involved in civilian preparedness for terrorist attack: planners, administrators, responders, medical professionals, public health and emergency personnel, and technology designers and engineers.




The Antidote


Book Description

In 1989, the charismatic Joshua Boger left Merck, then America's most admired business, to found a drug company that would challenge industry giants and transform health care. Journalist Barry Werth described the company's tumultuous early days during the AIDS crisis in The Billion-Dollar Molecule, a celebrated classic of science and business journalism. Now he returns to tell the story of Vertex's bold endurance and eventual success. The pharmaceutical business is America's toughest and one of its most profitable. It's riskier and more rigorous at just about every stage than any other business, from the towering biological uncertainties inherent in its mission to treat disease; to the 30-to-1 failure rate in bringing out a successful medicine; to the multibillion-dollar cost of ramping up a successful product; to operating in the world's most regulated industry, matched only by nuclear power. Werth captures the full scope of Vertex's 25-year drive to deliver breakthrough medicines.--From publisher description.




Betrayal in Psychotherapy and Its Antidotes


Book Description

Betrayal in all its forms has been and is an ever present reality in every area of life--politics, business, and human relationships to name a few. Recent publications have chronicled the unethical actions of mental health and other human service professionals, yet the psychology of betrayal has received little public interest and attention. This book explores the many issues relating to psychotherapy and betrayal. The contributing authors of Betrayal in Psychotherapy and its Antidotes present the various faces of betrayal as may be encountered by therapists in the office or in the profession. They challenge therapists to understand the violations of trust that can occur within the therapeutic relationship. Readers are reminded that the trauma of betrayal manifests itself within all patients, regardless of of the nature and expression of psychopathology. More importantly, the authors define betrayal as experienced with specific cases and they attempt to bring out underlying principles that are useful to therapists and the larger professional community. Readers will find their understanding of the concept of betrayal much expanded from the chapters in Betrayal in Psychotherapy and its Antidotes. For example, betrayal is discussed as a failure in the interpersonal or inter-subjective relationship between therapist and client in one chapter as opposed to the concept of betrayal as an act calculated to lead another person astray, an act of deception or treachery, and a breach of confidence and trust as considered in another chapter. Other approaches to betrayal and psychotherapy include: how to determine what is betrayal in psychotherapy the use of case examples to establish the importance of the therapist striving to remain true to the genuine potentiality of a patient how to avoid colluding with the patient’s rejection of life the work of Alice Miller, a psychoanalyst by training, and the betrayal of children by abuse the paradoxical nature of psychiatric practice and its necessary reliance upon moral reasoning an investigation on the link between therapists’personal maturity and the success of therapy how traditional humanistic and analytic therapies can entrap both therapist and patient into a betrayal of self and the relationship implications of the “betrayal of the feminine” in males and their work with clients in a psychotherapy setting a case portrayal of “Teddy”--the betrayal of the betrayed




Biological Toxins and Bioterrorism


Book Description

Biological toxins are an important part of our world, a reality with which we need to cope, so in parallel with understanding their mechanisms of action and thereby improving our fundamental knowledge, there are successful efforts to utilize them as therapeutics against some debilitating human and animal diseases. In view of the complexity of different types of biotoxins and the broad range of toxin structure, physiology, utility, and countermeasures including regulatory issues, it was thus aimed to compile a book on biotoxins and bioweapons. This reference work in the Toxinology handbook series gathers together knowledge from around the globe about naturally inspired and manufactured biological weapons. The authors describe how they work; how authorities may detect their presence, prevent their use, and diagnose their impacts; and the means by which medical and paramedical professionals may treat victims. Also described are how they have been used to further our knowledge and what insights they have given us into evolutionary and physiological processes. Finally, it is also discussed how these toxins can be used as therapeutics and what the implications of such therapeutics are to their use as biothreat agents. This volume provides a reference accessible to scientists, educators, and medical experts alike with an interest in biotoxins, focusing on the major toxins used as bioweapons. Regulatory agencies will also benefit from the information provided in this book. Some in the intended audience may need to understand how they elicit their effects and how we can defend ourselves against them. Others may be interested in the sometimes colorful histories that surround this subset of biotoxins that can be and, in some cases, have been used as weapons.




Poisonous Plants and Phytochemicals in Drug Discovery


Book Description

Focusing on phytochemicals and their potential for drug discovery, this book offers a comprehensive resource on poisonous plants and their applications in chemistry and in pharmacology. Provides a comprehensive resource on phytotoxins, covering historical perspectives, modern applications, and their potential in drug discovery Covers the mechanisms, benefits, risks and management protocols of phytotoxins in a scientific laboratory and the usefulness in drug discovery Presents chapters in a carefully designed, clear order, making it an ideal resource for the academic researcher or the industry professional at any stage in their career